Elena Eraso

Research Field

At present, data about the cross-reactivity of Blomia spp. comes from studies made among different genera of mites, and no results have been published involving different species of the genus Blomia.The aim of this study was to find out the level of cross-reactivity between the two main species of Blomia causing allergy, and its implication in the diagnosis of Blomia sensitization.Using extracts from optimal growth phases of Blomia kulagini (Zakhvatkin, 1936) and Blomia tropicalis (van Bronswijk, Cock and Oshima, 1973) as allergenic material, the allergenic cross-reactivity between both house dust mites was evaluated by means of cutaneous tests, specific IgE values, ImmunoCAP-inhibition and SDS-PAGE-IgE-immunoblotting-inhibition.The results demonstrated that IgE-binding components belonging to both species are very similar from the immunological point of view, showing high correlations between both species when using cutaneous tests (R2=0.915) or specific IgE (R2=0.980). ImmunoCAP-inhibition and SDS-PAGE-IgE-Immunoblotting-inhibition probed with human sera, showed a total inhibition of specific IgE reactions by the heterologous antigens.The results obtained strongly suggest the great resemblance between the allergenic composition of both species.

Cross-reactivity

Aeroallergen

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Citations (12)

Actividad antifúngica in vitro de voriconazol: Nuevos datos después de los primeros años de experiencia clínica

Revista Iberoamericana de Micología (2007)

Guillermo Quindós Alfonso Javier Carrillo‐Muñoz Elena Eraso Rafael Cantón Javier Pemán

Azole

Candida glabrata

10.1016/s1130-1406(07)70043-8

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Citations (12)

Molecular identification of Candida auris by PCR amplification of species-specific GPI protein-encoding genes

International Journal of Medical Microbiology (2018)

Alba Ruiz‐Gaitán Jordan Fernández-Pereira Eulogio Valentı́n María Ángeles Tormo‐Más Elena Eraso

Candida auris

Primer (cosmetics)

10.1016/j.ijmm.2018.06.014

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Citations (44)

Evaluación comparativa de ATB Fungus 2 y Sensititre YeastOne en el estudio de la sensibilidad in vitro de Candida a los antifúngicos

Revista Iberoamericana de Micología (2008)

Elena Eraso Maite Ruesga María Villar-Vidal Alfonso Javier Carrillo‐Muñoz Ana Espinel‐Ingroff

Candida krusei

Candida dubliniensis

Candida glabrata

Candida infections

Flucytosine

10.1016/s1130-1406(08)70002-0

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Citations (23)

Early detection of subclinical left ventricular dysfunction by speckle-tracking echocardiography after radiation therapy for breast cancer: results from the MEDIRAD EARLY-HEART study

Médéa Locquet D. Spport A.P.G. Crijns Elena Eraso Ferràn Guedea

Subclinical infection

Speckle tracking echocardiography

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Presencia de Candida en la estomatitis aftosa recidivante

Revista Iberoamericana de Micología (2013)

Asier Eguia Cristina Marcos‐Arias Elena Eraso Guillermo Quindós José Manuel Aguirre

10.1016/j.riam.2013.03.003

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Citations (1)

Sertaconazole: an antifungal agent for the topical treatment of superficial candidiasis

Expert Review of Anti-infective Therapy (2013)

Alfonso Javier Carrillo‐Muñoz Cristina Tur‐Tur Gustavo Giusiano Cristina Marcos‐Arias Elena Eraso

Sertaconazole is a useful antifungal agent against mycoses of the skin and mucosa, such as cutaneous, genital and oral candidiasis and tinea pedis. Its antifungal activity is due to inhibition of the ergosterol biosynthesis and disruption of the cell wall. At higher concentrations, sertaconazole is able to bind to nonsterol lipids of the fungal cell wall, increasing the permeability and the subsequent death of fungal cells. Fungistatic and fungicidal activities on Candida are dose-dependent. The antifungal spectrum of sertaconazole includes deramophytes, Candida, Cryptococcus, Malassezia and also Aspergillus, Scedosporium and Scopulariopsis. Sertaconazole also shows an antimicrobial activity against streptococci, staphylococci and protozoa (Trichomonas). In clinical trials including patients with vulvovaginal candidiasis, a single dose of sertaconazole produced a higher cure rate compared with other topical azoles such as econazole and clotrimazole, in shorter periods. Sertaconazole has shown an anti-inflammatory effect that is very useful for the relief of unpleasant symptoms

Econazole

Clotrimazole

10.1586/eri.13.17

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Citations (35)

P1956 In vitro activity of amphotericin B and anidulafungin against Candida albicans biofilms

International Journal of Antimicrobial Agents (2007)

A. Valentín E. Cantóon J. Pemáan Miquel Bosch Elena Eraso

Anidulafungin

Echinocandins

10.1016/s0924-8579(07)71795-8

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