William E. Fann

Baylor College of Medicine

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Co-Authors

David S. Janowsky

University of California, San Diego

John M. Davis

University of Illinois Chicago

Bruce W. Richman

Access to Wholistic and Productive Living Institute

Wesley M. Pitts

University of Mississippi

Jeanine C. Wheless

University of North Carolina at Chapel Hill

John M. Davis

Mayo Clinic in Arizona

Gerald M. McKenzie

King's College London

John H. Cavanaugh

Massachusetts Institute of Technology

Alex D. Pokorny

Elektrobit (Finland)

C R Lake

University of Michigan–Dearborn

Cooperative Institutions

Baylor College of Medicine

Karolinska Institutet

National Institutes of Health

United States Department of Veterans Affairs

Duke Medical Center

Vanderbilt University

Duke University Hospital

Duke University

Harvard University

National Institute of Environmental Health Sciences

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Physostigmine in Rigid Huntington’s Disease

Stereotactic and Functional Neurosurgery (1973)

William E. Fann C Gerber Gerald M. McKenzie

Physostigmine, a centrally active anticholihesterase agent, was given to three patients with rigid Huntington’s disease (RHD). Neurologic examinations before, during and after the administration showed no change in the manifestations of RHD. The theoretical implications of these data are discussed.

Physostigmine

10.1159/000102851

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Citations (7)

Integrating Pharmacotherapy and Psychotherapy

American Journal of Psychiatry (1993)

William E. Fann

Table of contents

10.1176/ajp.150.2.340

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Citations (0)

Some Drug-Drug Interactions Involving Psychotropic Agents

Springer eBooks (1975)

William E. Fann Bruce W. Richman

Compendium

Psychotropic drug

Psychotropic Agent

Iproniazid

10.1007/978-1-4615-7697-6_13

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Interactions of Psychotropic Drugs in the Elderly

Postgraduate Medicine (1973)

Carl Eisdorfer William E. Fann

The elderly patient, especially if mentally ill, is likely to be taking several medications. When some of the psychotropic drugs are used concomitantly or in combination with other agents (e.g., antihypertensives), therapeutic effects may be nullified or toxicity may result. Cautious prescribing habits and knowledge of the mechanisms of drug interactions are necessary to prevent harmful sequelae.

Psychotropic Agent

Psychotropic drug

10.1080/00325481.1973.11713402

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Citations (6)

Angiotensin effect on uptake of norepinephrine by synaptosomes

Life Sciences (1972)

David S. Janowsky John M. Davis William E. Fann J. A. Freeman Rosemary Nixon

Synaptosome

10.1016/0024-3205(72)90236-6

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Citations (21)

Tardive Dyskinesia and Other Drug-Induced Movement Disorders

Springer eBooks (1980)

William E. Fann

Tardive dyskinesia

Movement Disorders

10.1007/978-94-011-6381-1_21

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Citations (14)

Effect of phenothiazines on reaction time in schizophrenics

Journal of Psychiatric Research (1970)

Joan M. Held Rue L. Cromwell Elisabeth Frank William E. Fann

10.1016/0022-3956(70)90008-7

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Citations (50)

Amantadine versus trihexyphenidyl in the treatment of neuroleptic- induced parkinsonism

American Journal of Psychiatry (1976)

William E. Fann C. Raymond Lake

Amantadine is a putative dopaminergic compound known to be therapeutically effective in idiopathic and postencephalitic Parkinson's disease. In a double-blind placebo-controlled crossover study of 39 psychiatric inpatients, amantadine and trihexyphenidyl were equally effective in treating drug-induced parkinsonism, and amantadine produced fewer and less severe side effects. The authors suggest that amantadine is an effective alternative to atropine-like agents, with fewer implications for long-term risk of tardive dyskinesia.

Amantadine

Trihexyphenidyl

10.1176/ajp.133.8.940

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Citations (71)

Drug induced parkinsonism. A re-evaluation.

PubMed (1975)

William E. Fann C R Lake Bruce W. Richman

Source

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Citations (11)

DEANOL (D), METHYLPHENIDATE (M), CYPROHEPTADINE (C), VS PLACEBO (P) IN TARDIVE DYSKINESIA