<p>Supplementary Figure S1. Analytical workflow for the C-CAT, GENIE, and TCGA cohorts.</p><p>Supplementary Figure S2. Comparison of targeted gene panels.</p><p>Supplementary Figure S3. Comparison of genetic alterations in C-CAT and GENIE cohorts.</p><p>Supplementary Figure S4. Comparison of mutation frequency, type, and position in C-CAT and GENIE cohorts.</p><p>Supplementary Figure S5. Co-occurring and mutually exclusive relationships across cohorts.</p><p>Supplementary Figure S6. Co-occurring and mutually exclusive relationships across cancer types/subtypes.</p><p>Supplementary Figure S7. Co-occurring and mutually exclusive relationships using a permutation approach.</p><p>Supplementary Figure S8. Co-occurring and mutually exclusive relationships across driver mutations in epigenetic regulators.</p><p>Supplementary Figure S9. Functional and prognostic relevance of driver mutations in epigenetic regulators.</p>
