To evaluate Magnesium (Mg) effectiveness in the treatment of primary dysmenorrhea, 30 volunteer dysmenorrheic women of mean age 22.6 years were selected from the out-patients of the Dept. of Obstetrics and Gynaecology of the University of Parma during the period January-December 1989. Patients affected by secondary dysmenorrhea were excluded from the trial. The women considered were asked to self-evaluate their menstrual pain for 6 subsequent cycles using the VAS (Visual Analogue Scale). In the first cycle, as control, no drug was administered; in the following ones, every woman was given 4.5 mg oral Mg Pidolate in 3 administrations daily, from the 7th day preceding the onset of menses till the 3rd day of menstruation. Data were statistically analyzed. In Mg-treated cycles compared with the control one, first day dysmenorrhea progressively decreased, with a significant drop (p < 0.05) from the 1st to the 6th cycle. A similar trend, but not statistically significant, was seen for the 2nd and 3rd day of cycle. No side effect was remarked. These data suggest Mg administration to be a reliable therapy of primary dysmenorrhea.
Recent knowledge on the pathogenetic mechanisms which are thought to be responsible for primary dysmenorrhea in most young females allow us to abandon old therapeutical approaches for several medical solutions with high effectiveness rates. But a number of patients remain for whom these treatments are not suitable or not effective. Mainly for these patients, today we can offer a valid alternative, a new kind of electroanalgesy, TENS, now easier to use owing to the miniaturization of the machine. In fact, in two groups of patients resistant or insensitive to modern medical therapies, we obtained good analgesia during the menstrual period, without important side effects and with high compliance by the patients.