Laura González-Garrido

Universidad de León

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Sofia N. Wasterlain

University of Coimbra

Susana Gómez‐González

Center for Climate and Resilience Research

NŠ

Nataša Šarkić

National Library of Serbia

Johannes Krause

Max Planck Institute for Evolutionary Anthropology

Judith Neukamm

University of Tübingen

Ana María Silva

University of Lisbon

Meriam Guellil

University of Tartu

José M. Gonzalo‐Orden

Universidad de León

John Robb

University of Cambridge

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Д. С. Коробов

Institute of Archaeology

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University of Coimbra

Centre for Research in Anthropology

University of Tübingen

University of Tartu

Estonian Biocentre

Max Planck Institute for the Science of Human History

Universidad de León

University of Cambridge

Universidad de Zaragoza

University of Zurich

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El empresario individual y las tendencias actuales a limitar su responsabilidad

Laura González-Garrido

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Congenital syphilis or mercury treatment: dental alterations in a twelfth- or thirteenth-century child from Medinaceli, Soria, Spain

HOMO (2020)

Susana Gómez‐González Consuelo Roca de Togores Muñoz Laura González-Garrido

Congenital syphilis

Mercury

10.1127/homo/2020/1173

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Citations (2)

Hábitos de vida, caries y desgaste dental en una población medieval de la montaña leonesa.

Laura González-Garrido Susana Gómez‐González Luis Caro Dobón

OBJETIVO: Analizar la frecuencia de la caries y el grado de desgaste dental, asi como la interaccion entre ambas; con la finalidad de aproximarse al tipo de dieta, la estratificacion social de la comunidad y las enfermedades que los individuos de una poblacion medieval de alta montana han podido padecer a lo largo de su vida. MATERIAL Y METODOS: El estudio se ha realizado en 19 individuos adultos correspondientes a la necropolis medieval de “El Barrejo” (ss. XII-XIII) localizada en Cordinanes y ubicada en la alta montana occidental leonesa (noroeste de Espana). De la totalidad de los individuos estudiados se han analizado 358 dientes y 609 alveolos dentales, excluyendo los casos donde la denticion se encuentra muy deteriorada. La caries ha sido clasificada mediante inspeccion visual en funcion de su intensidad y localizacion. Asi mismo, el estudio del desgaste dental ha sido realizado mediante el analisis del grado de intensidad. Las perdidas dentales ante y post mortem tambien han sido registradas. RESULTADOS: La frecuencia de caries observada en esta poblacion es del 24,30%, existiendo un predominio de su localizacion en la zona interproximal (57,47%). El grado de desgaste dental corresponde a un grado entre bajo y moderado (5,55) sin embargo, se observan valores mas elevados en los dientes anteriores. CONCLUSION: Estos resultados se aproximan a los observados en otras poblaciones vinculadas a una economia de subsistencia, condicionada por la restrictiva ecologia del medio, como ocurre en la alta montana leonesa.

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Muelas y molinos: salud dentomaxilar en el norte de la península ibérica (siglos IX-XIX)

Laura González-Garrido

10.18002/10612/18592

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Multi-headed (bifid and trifid) mandibular condyles in archaeological contexts: Two posttraumatic cases

Archives of Oral Biology (2021)

Laura González-Garrido Susana Gómez‐González José M. Gonzalo‐Orden Sofia N. Wasterlain

Mandible (arthropod mouthpart)

10.1016/j.archoralbio.2021.105326

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Decomposition dynamics of herbaceous species in riparian areas of the Henares river.

T. Martínez-Martínez Juan A. Delgado Laura González-Garrido R. Reiné O. Barrantes

Herbaceous plant

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Additional file 3 of Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes

Figshare (2021)

Saskia Pfrengle Judith Neukamm Meriam Guellil Marcel Keller Martyna Molak

Additional file 3: Table S5. SNP distance matrix.

Mycobacterium leprae

Dynamics

10.6084/m9.figshare.16746764

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Stafne’s bone defects from Spain: report of four cases and brief archaeological literature review

International Journal of Paleopathology (2020)

Laura González-Garrido Susana Gómez‐González José M. Gonzalo‐Orden Sofia N. Wasterlain

Mandible (arthropod mouthpart)

Osteology

Mandibular canal

10.1016/j.ijpp.2020.08.001

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Osseous mass in a maxillary sinus of an adult male from the 16th–17th-century Spain: Differential diagnosis

International Journal of Paleopathology (2020)

Laura González-Garrido Claudina González Rosa Ramos Gaspar Sofia N. Wasterlain

Radiodensity

Sinus (botany)

10.1016/j.ijpp.2020.08.003

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Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes

BMC Biology (2021)

Saskia Pfrengle Judith Neukamm Meriam Guellil Marcel Keller Martyna Molak

Hansen's disease (leprosy), widespread in medieval Europe, is today mainly prevalent in tropical and subtropical regions with around 200,000 new cases reported annually. Despite its long history and appearance in historical records, its origins and past dissemination patterns are still widely unknown. Applying ancient DNA approaches to its major causative agent, Mycobacterium leprae, can significantly improve our understanding of the disease's complex history. Previous studies have identified a high genetic continuity of the pathogen over the last 1500 years and the existence of at least four M. leprae lineages in some parts of Europe since the Early Medieval period.Here, we reconstructed 19 ancient M. leprae genomes to further investigate M. leprae's genetic variation in Europe, with a dedicated focus on bacterial genomes from previously unstudied regions (Belarus, Iberia, Russia, Scotland), from multiple sites in a single region (Cambridgeshire, England), and from two Iberian leprosaria. Overall, our data confirm the existence of similar phylogeographic patterns across Europe, including high diversity in leprosaria. Further, we identified a new genotype in Belarus. By doubling the number of complete ancient M. leprae genomes, our results improve our knowledge of the past phylogeography of M. leprae and reveal a particularly high M. leprae diversity in European medieval leprosaria.Our findings allow us to detect similar patterns of strain diversity across Europe with branch 3 as the most common branch and the leprosaria as centers for high diversity. The higher resolution of our phylogeny tree also refined our understanding of the interspecies transfer between red squirrels and humans pointing to a late antique/early medieval transmission. Furthermore, with our new estimates on the past population diversity of M. leprae, we gained first insights into the disease's global history in relation to major historic events such as the Roman expansion or the beginning of the regular transatlantic long distance trade. In summary, our findings highlight how studying ancient M. leprae genomes worldwide improves our understanding of leprosy's global history and can contribute to current models of M. leprae's worldwide dissemination, including interspecies transmissions.

Mycobacterium leprae

Ancient DNA

10.1186/s12915-021-01120-2

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Citations (31)