Vitamin E is one of the most important lipid-soluble antioxidants. It is essential for the neurological function but its role in the central nervous system has not fully been elucidated. It is known that tocopherol acts in protecting cell membranes from oxidative damage and it can act as an anti-in?ammatory agent, which may also be neuroprotective, as well as regulating speci?c enzymes. There is growing evidence that oxidative stress plays a key role in the pathophysiology of several neurodegenerative disorders. These diseases are defined by the progressive loss of speci?c neuronal cell populations and are associated with protein aggregates. We reviewed some aspects related to the role of antioxidant properties of Vitamin E in preventing and/or curing neurodegenerative disorders such as the Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, ataxia, tardive dyskinesia and Huntington’s disease.

Tardive dyskinesia

10.4236/wjns.2012.24033

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Citations (3)

Ischemic strokes following a viper bite (cerastes cerastes)

Journal of the Neurological Sciences (2015)

Fatima Imounan M. Cheikh Saad Bouh Amine El Alaoui

Antivenom

VIPeR

Stroke

Hemiparesis

10.1016/j.jns.2015.08.1361

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[Clinical and environmental aspects of amyotrophic lateral sclerosis in moroccan population: a study of 60 cases].

PubMed (2015)

Fatima Imounan S. Lahbouje Y. Hsaini W. Regragui Ait Ben Haddou el H

Amyotrophic lateral sclerosis (ALS) is the most common disease of the motor neuron disease. Its etiology remains unknown but several studies incriminate the environmental factors in its genesis.of this study was to describe the epidemiological, clinical and environmental aspects of ALS in Moroccan population.60 ALS patients were recruited over a period of 5 years from January 2008 to September 2012. Patients were evaluated by detailed record of exploitation. Statistical analysis was performed using SPSS 13.0.The average age of the population was 52.1 ± 11.2 years with a sex ratio of M/F = 1.5. The average age of onset was 50 ± 11.7 years. In the group of patients exposed to toxic a significantly higher proportion of solvent exposure was found (p = 0.02). However there was no significant association with exposure to heavy metals, pesticides, or with toxic and eating habits. ALS is more frequent in the west region of Morocco (p = 0.03).The positive association between exposure to solvents and ALS found in our population has been reported in the literature. The frequency of the ALS early west region suggests may be environmental or genetic origin. These results are preliminary and require a multicenter study to have more data and better highlight the environmental characteristics of ALS in the Moroccan population.

Etiology

Population study

Source

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Complications neurologiques dues à l’intoxication aux graines de ricin

Revue Neurologique (2012)

Fatima Imounan El Hachmia Ait Ben Haddou Jehanne Aasfara W. Regragui Ali Benomar

Mushroom poisoning

10.1016/j.neurol.2012.01.358

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