Maria Gabriella Brizi

Aim of the present study was to evaluate the clinical correlates of small bowel CT patterns in patients with Crohn's disease (CD), as compared to barium studies and endoscopic findings, as far as parameters of disease activity are concerned.Thirty five patients with pathologically proven CD were studied by means of helical single detector CT (13) or multidetector CT (22), after administration of low density contrast by mouth (13) or by nasojeunal tube (22). Eight hours later, all patients were studied with barium administered by mouth (13) or with barium and methilcellulose administered by nasojeunal tube (22). Clinical activity was assessed by CDAI score, ESR, CRP, alpha1 glycoprotein and fibrinogen levels. In twenty one patients, colonoscopy was also performed.Sensitivity of small bowel CT versus endoscopy was of 88% while sensitivity of barium studies was of 77% versus endoscopic findings, and it reached 100% for the combination of both exams. We found positive correlations between the detection at CT of "target sign" and a CDAI score > 150 or abnormal values of CRP, ESR, alpha1 glycoprotein. Abnormal ESR or fibrinogen levels were correlated with the detection of fistulas at CT scans. The diameter of enlarged mesenteric lymph nodes was correlated with alpha1 glycoprotein values. No similar correlations were detected for contrast radiology findings.This study underscores the clinical usefulness of performing small bowel CT in adjunct to conventional diagnostic studies in Crohn's disease patients. CT findings (either by oral route or nasojeunal tube) correlate with parameters of disease activity.

Barium sulfate

Barium enema

Source

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Citations (14)

Dynamic magnetic resonance pancreatography after secretin stimulation in chronic pancreatitis

Digestive and Liver Disease (2000)

Roberto Manfredi Guido Costamagna Massimiliano Mutignani A. Tringali Maria Gabriella Brizi

Secretin

10.1016/s1590-8658(00)80655-6

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Citations (0)

Anticoagulant therapy in the treatment of splanchnic vein thrombosis associated to acute pancreatitis: a 3-year single-centre experience

Internal and Emergency Medicine (2020)

Danilo Pagliari Rossella Cianci Maria Gabriella Brizi Francesco Antonio Mancarella Massimiliano Musso

Fondaparinux

Vitamin K antagonist

10.1007/s11739-019-02271-5

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Citations (22)

A review of Magnetic Resonance Enterography classification and quantitative evaluation of active disease in patients with Crohn's disease

Clinical Imaging (2020)

Laura Maria Minordi Luigi Larosa Alfredo Papa Giovanni Cimino Antonio Bevere

10.1016/j.clinimag.2020.06.006

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Citations (15)

Endoscopic ultrasound-guided histological diagnosis of a mucinous non-neoplastic pancreatic cyst using a specially designed through-the-needle microforceps

Endoscopy (2016)

Fabia Attili Danilo Pagliari Mihai Rimbaş Frediano Inzani Maria Gabriella Brizi

Solitary uniloculated pancreatic cysts pose a major diagnostic dilemma. Cystic fluid carcinoembryonic antigen (CEA) concentration and cytology have low sensitivity in distinguishing mucinous from non-mucinous cysts [1], leading to frequent misdiagnoses and unnecessary surgical interventions [2]. Recently evaluated molecular markers seem very accurate, but they are not widely available in clinical practice [3].

Carcinoembryonic antigen

Endoscopic Ultrasound

Mucinous cystadenoma

Pancreatic cyst

Mucinous Tumor

10.1055/s-0042-108194

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Citations (24)

Crohn disease: magnetic resonance enteroclysis

Abdominal Radiology (2004)

Gabriele Masselli Maria Gabriella Brizi Angela Parrella Laura Maria Minordi A Vecchioli

10.1007/s00261-003-0116-9