Caitlin E. Older

United States Department of Agriculture

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Aline Rodrigues Hoffmann

Texas A&M University

Fernando Y. Yamamoto

Mississippi State University

Matt J. Griffin

Mississippi State University

Alison Diesel

Texas A&M University

Delbert M. Gatlin

Texas A&M University System

Geoffrey C. Waldbieser

United States Department of Agriculture

Courtney Meason‐Smith

Texas A&M University

Sara D. Lawhon

Texas A&M University

Jan S. Suchodolski

Texas A&M University

Cynthia Ware

Mississippi State University

Cooperative Institutions

Texas A&M University

University of California, Davis

United States Department of Agriculture

Agricultural Research Service

Mississippi State University

University of Georgia

Auburn University

National Cold Water Marine Aquaculture Center

Mitchell Institute

Mississippi Delta Community College

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Dietary fishmeal replacement by black soldier fly larvae meals affected red drum (Sciaenops ocellatus) production performance and intestinal microbiota depending on what feed substrate the insect larvae were offered

Animal Feed Science and Technology (2021)

Fernando Y. Yamamoto Blaine A. Suehs Matthew Ellis Paul R. Bowles Caitlin E. Older

Hermetia illucens

10.1016/j.anifeedsci.2021.115179

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Citations (19)

The feline skin microbiota: The bacteria inhabiting the skin of healthy and allergic cats

PLoS ONE (2017)

Caitlin E. Older Alison Diesel Adam P. Patterson Courtney Meason‐Smith Timothy J. Johnson

Background The skin is inhabited by a multitude of microorganisms. An imbalance of these microorganisms is associated with disease, however, the causal relationship between skin microbiota and disease remains unknown. To describe the cutaneous bacterial microbiota of cats and determine whether bacterial dysbiosis occurs on the skin of allergic cats, the skin surfaces on various regions of 11 healthy cats and 10 allergic cats were sampled. Methodology/Principal findings Genomic DNA was extracted from skin swabs and sequenced using primers that target the V4 region of the bacterial 16S rRNA. The bacterial sequences from healthy cats revealed that there are differences in species diversity and richness between body sites and different epithelial surfaces. Bacterial communities preferred body site niches in the healthy cats, however, the bacterial communities on allergic cat skin tended to be more unique to the individual cat. Overall, the number of bacterial species was not significantly different between the two health status groups, however, the abundances of these bacterial species were different between healthy and allergic skin. Staphylococcus, in addition to other taxa, was more abundant on allergic skin. Conclusions/Significance This study reveals that there are more bacterial species inhabiting the skin of cats than previously thought and provide some evidence of an association between dysbiosis and skin disease.

Dysbiosis

Microbiological culture

10.1371/journal.pone.0178555

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Citations (54)

Dietary supplementation of mineral nanoparticles for channel catfish (Ictalurus punctatus)

Fish Physiology and Biochemistry (2024)

Vitor Fernandes Silva José Luiz Pedreira Mouriño Maurício Laterça Martins Pedro Luiz Pucci Figueiredo de Carvalho Edgar Junio Damasceno Rodrigues

Edwardsiella ictaluri

10.1007/s10695-024-01378-7

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Citations (1)

Exploring the nutritional value of corn fermented protein as a replacement for soybean meal in diets for juvenile channel catfish (Ictalurus punctatus): Impacts on production performance, intestinal health, and disease resistance

Aquaculture (2024)

Fernando Y. Yamamoto Jing Huang C. Camilo Suarez-Barazeta Steven R. Craig Caitlin E. Older

10.1016/j.aquaculture.2024.740824

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Citations (2)

The Nature and Functions of Vertebrate Skin Microbiota

Springer eBooks (2022)

Aline Rodrigues Hoffmann Caitlin E. Older Mayane Faccin

Dysbiosis

10.1007/978-3-030-91051-8_9

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Citations (3)

Reference genomes of channel catfish and blue catfish reveal multiple pericentric chromosome inversions

BMC Biology (2023)

Geoffrey C. Waldbieser Shikai Liu Zihao Yuan Caitlin E. Older Dongya Gao

Abstract Background Channel catfish and blue catfish are the most important aquacultured species in the USA. The species do not readily intermate naturally but F 1 hybrids can be produced through artificial spawning. F 1 hybrids produced by mating channel catfish female with blue catfish male exhibit heterosis and provide an ideal system to study reproductive isolation and hybrid vigor. The purpose of the study was to generate high-quality chromosome level reference genome sequences and to determine their genomic similarities and differences. Results We present high-quality reference genome sequences for both channel catfish and blue catfish, containing only 67 and 139 total gaps, respectively. We also report three pericentric chromosome inversions between the two genomes, as evidenced by long reads across the inversion junctions from distinct individuals, genetic linkage mapping, and PCR amplicons across the inversion junctions. Recombination rates within the inversional segments, detected as double crossovers, are extremely low among backcross progenies (progenies of channel catfish female × F 1 hybrid male), suggesting that the pericentric inversions interrupt postzygotic recombination or survival of recombinants. Identification of channel catfish- and blue catfish-specific genes, along with expansions of immunoglobulin genes and centromeric Xba elements, provides insights into genomic hallmarks of these species. Conclusions We generated high-quality reference genome sequences for both blue catfish and channel catfish and identified major chromosomal inversions on chromosomes 6, 11, and 24. These perimetric inversions were validated by additional sequencing analysis, genetic linkage mapping, and PCR analysis across the inversion junctions. The reference genome sequences, as well as the contrasted chromosomal architecture should provide guidance for the interspecific breeding programs.

Chromosomal inversion

Reproductive isolation

10.1186/s12915-023-01556-8

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Histoplasmosis and multicentric lymphoma in a Nubian goat

Journal of Veterinary Diagnostic Investigation (2019)

Samantha N. Schlemmer Alycia P. Fratzke Philippa Gibbons Brian F. Porter Joanne Mansell

Following treatment for pneumonia, a 1-y-old female Nubian goat was presented because of a persistent fever for 3 mo and peripheral lymphadenopathy for 1 mo. Cytology and histology of the superficial cervical and prefemoral lymph nodes demonstrated a moderate-to-marked “left-shifted” lymphoid population, suggestive of lymphoma, and extremely rare extracellular, 2–4 µm, oval, basophilic yeast, consistent with Histoplasma capsulatum. On immunohistochemistry, >95% of the lymphocytes demonstrated positive cytoplasmic and membranous immunoreactivity for CD3. Histoplasma spp. urine antigen and serum antibody testing were positive and negative, respectively. Panfungal PCR and sequencing of DNA extracted from scrolls of formalin-fixed, paraffin-embedded tissue yielded matches to H. capsulatum with 99–100% identity. Given the poor prognosis and persistent pyrexia, the animal was euthanized. Postmortem examination confirmed concurrent multicentric, intermediate-size, T-cell, lymphoblastic lymphoma and histoplasmosis; lesions consistent with intestinal coccidiosis and suspected pulmonary Rhodococcus equi were also noted. Although dimorphic fungi have been described previously in goats, lesions of Histoplasma spp. had not been documented in this species, to our knowledge. Given the low disease burden, it is suspected that the lymphoma was primary, leading to an immunocompromised state and development of secondary, opportunistic infections.

Histoplasma

Dimorphic fungus

10.1177/1040638719868810

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Citations (6)

Characterization of the cutaneous mycobiota in healthy and allergic cats using next generation sequencing

Courtney Meason‐Smith Alison Diesel Adam P. Patterson Caitlin E. Older Timothy J. Johnson

This chapter characterizes the mycobiota of feline skin using next generation sequencing (NGS) and to determine whether alterations to the mycobiota exist in feline allergic skin diseases. It also identifies reduced diversity at mucosal sites and a predominance of Dothideomycetes (Cladosporium, Alternaria and Epiccocum) similar to what has been reported for canine skin. The allergic cats enrolled in the chapter were diagnosed with a range of hypersensitivity dermatitis (HD) lesions. Two types of statistical testing, Kruskal-Wallis and linear discriminant analysis (LDA) effect size (LEfSe), were performed to determine whether specific taxa (phylum, class, order, family or genus levels) were differentially abundant between cats or body sites. The Kruskal-Wallis tests revealed that nine taxa were significantly different between groups including the genus Epicoccum and nonclassified Capnodiales order, which were also identified as significantly more abundant in the healthy group by LEfSe analysis.

Mycobiota

UniFrac

10.1002/9781119278368.ch4.2

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Citations (11)

The feline cutaneous and oral microbiota are influenced by breed and environment

PLoS ONE (2019)

Caitlin E. Older Alison Diesel Sara D. Lawhon Cintia R. R. Queiroz Luan Cleber Henker

Previous research revealed the feline skin bacterial microbiota to be site-specific and the fungal microbiota to be individual-specific. The effect of other factors, such as genotype and environment, have not yet been studied in cats, but have been shown to be potentially important in shaping the cutaneous microbiota of other animals. Therefore, the objectives of this study were to evaluate the effect of these factors on the bacterial and fungal microbiota of feline skin and oral cavity. The influence of genotype was assessed through the analysis of different cat breeds, and the influence of environment through comparison of indoor and outdoor cats. DNA was extracted from skin and oral swabs, and bacterial and fungal next-generation sequencing were performed. Analysis of the skin microbiota of different cat breeds revealed significant differences in alpha diversity, with Sphynx and Bengal cats having the most diverse communities. Many taxa were found to be differentially abundant between cat breeds, including Veillonellaceae and Malassezia spp. Outdoor environment exposure had considerable influence on beta diversity, especially in the oral cavity, and resulted in numerous differentially abundant taxa. Our findings indicate that the oral bacterial microbiota and both fungal and bacterial microbiota of feline skin are influenced by breed, and to a lesser degree, environment.

Malassezia

Commensalism

10.1371/journal.pone.0220463

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Citations (48)

Additional file 2 of Reference genomes of channel catfish and blue catfish reveal multiple pericentric chromosome inversions

Figshare (2023)

Geoffrey C. Waldbieser Shikai Liu Zihao Yuan Caitlin E. Older Dongya Gao

Additional file 2: Supplementary Table S7. Shared markers between blue catfish and channel catfish. Supplementary Table S10. Gene annotation of 508 gene families that were specific to channel catfish and blue catfish compared with other 14 representative fish species. Supplementary Table S11. Annotation of 1127 genes within 732 families that are specific to channel catfish. Supplementary Table S12. Annotation of 606 genes within 434 families that are specific to blue catfish.

10.6084/m9.figshare.22620863

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Citations (0)