Frank Vitinius

Robert Bosch Hospital

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Christian Albus

University Hospital Cologne

Martin Hellmich

University of Cologne

Yeşim Erim

Friedrich-Alexander-Universität Erlangen-Nürnberg

Stephanie Stock

University Hospital Cologne

Martina de Zwaan

Medizinische Hochschule Hannover

Kerstin Rhiem

University Hospital Cologne

Barbara Stein

Antwerp University Hospital

Anke Steckelberg

Martin Luther University Halle-Wittenberg

Anna Isselhard

University Hospital Cologne

Birte Berger‐Höger

Martin Luther University Halle-Wittenberg

Cooperative Institutions

University Hospital Cologne

119

University of Cologne

110

Centrum für Integrierte Onkologie

Klinik für Psychosomatik

Heidelberg University

Klinik und Poliklinik für Psychosomatik und Psychotherapie

Heinrich Heine University Düsseldorf

University Hospital Heidelberg

Charité - Universitätsmedizin Berlin

Friedrich-Alexander-Universität Erlangen-Nürnberg

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A pragmatic randomised controlled trial referring to a Personalised Self-management SUPport Programme (P-SUP) for persons enrolled in a disease management programme for type 2 diabetes mellitus and/or for coronary heart disease

Uwe Konerding Marcus Redaèlli Karolin Ackermann Sibel Altin Sebastian Appelbaum

Background: Type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD) are two chronic diseases that cause a tremendous burden.To reduce this burden, several programmes for optimising the care for these diseases have been developed.In Germany, so-called disease management programmes (DMPs), which combine components of Disease Management and the Chronic Care Model, are applied.These DMPs have proven effective.Nevertheless, there are opportunities for improvement.Current DMPs rarely address self-management of the disease, make no use of peer support, and provide no special assistance for persons with low health literacy and/or low patient activation.The study protocol presented here is for the evaluation of a programme that addresses these possible shortcomings and can be combined with current German DMPs for T2DM and CHD.This programme consists of four components:

Self-Management

Disease management

10.20378/irb-51693

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Perceived Psychotherapist's Empathy and Therapy Motivation as Determinants of Long-Term Therapy Success—Results of a Cohort Study of Short Term Psychodynamic Inpatient Psychotherapy

Frontiers in Psychiatry (2018)

Frank Vitinius Stephanie Tieden Martin Hellmich Holger Pfaff Christian Albus

Objective: Outcome predictors and determinants for treatment outcome of inpatient psychotherapy will be assessed in a follow-up-study. Sociodemographic factors and the level of depressiveness at admission, the perceived psychotherapist's empathy rated by patients and the therapy motivation as possible moderators of treatment outcome (reduction of depressive symptoms) are analyzed. Methods: In a cohort study, the outcome of inpatient multimodal psychotherapy was examined with Beck-Depression-Inventory (BDI) at admission (T1), discharge (T2) and at follow-up (1-3 years after treatment) (T3). Inclusion criteria were: Inpatient psychotherapy between 2007 and 2010 with a duration of at least 1 week and complete data set. The influence on therapy success of (1) sociodemographic factors, (2) the perceived psychotherapist's empathy rated by patients using the Consultation and Relational Empathy Measure (CARE), and (3) the therapy motivation of the patients rated by therapists are examined by means of correlation analysis, distribution comparisons and subsequently logistic regression. Results: Ninety-two (64 females, average age 39 yrs.) of 182 eligible patients participated in the follow-up survey. Duration of inpatient psychotherapy lasted 8.7 weeks ± 3.6 [min. 1, max. 33 weeks]. The perceived psychotherapist's empathy, therapy motivation, education level and depression at baseline had a significant impact on therapy success. Gender, age, and partnership were not significant. The length between discharge and follow-up had no influence on the results. Based on these variables a multiple logistic regression explained 42% of the variation (goodness-of-fit). Conclusion: Due to the shown relevance of the psychotherapist's empathy perceived by patients and the therapy motivation of patients for therapy success, both factors should be considered already at the beginning of the therapy. Consequently, they should be recognized in the context of postgraduate training and education.

Psychodynamic Psychotherapy

Depression

10.3389/fpsyt.2018.00660

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Citations (9)

Prevalence and Modifiable Determinants of Non-Adherence in Adult Kidney Transplant Recipients in a German Sample

Zeitschrift für psychosomatische Medizin und Psychotherapie (2016)

Sandra Reber Eva Morawa Lisa Stößel Sabine Jank Frank Vitinius

The aim of this cross-sectional study was to investigate the prevalence and the modifiable determinants of non-adherence in adult kidney transplant patients in follow-up care.In 74 patients at least six months post-transplant, self-reported adherence (Basel Assessment of Adherence to ImmunosuppressiveMedications Scale, BAASIS©), subjective experience and attitudes after transplantation (Medication Experience Scale for Immunosuppressants, MESI), and depression and anxiety (Hospital Anxiety and Depression Scale,HADSD) were assessed.Non-adherence to any of the four BAASIS© items was 24.3%. For the sub-dimensions: dose taking, drug holidays, timing deviation more than two hours from prescribed time, and dose reduction, the non-adherence levelswere 9.5%, 0%,17.6% and 2.7%, respectively. Marital status, negative beliefs towards immunosuppressants, and prominent anxiety and depression were associated with non-adherence.Screening for adherence and its indicators is of substantial importance in communication with renal transplant recipients. After detecting non-adherence, supportive interventions can be offered to the patients.

Depression

Marital status

Medication Adherence

Cross-sectional study

10.13109/zptm.2016.62.3.270

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Psychosomatisch-psychotherapeutische Aspekte in der Herztransplantationsmedizin (HTx)–Eine systematische Literaturübersicht

PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie (2009)

Frank Vitinius A M Worms Christian Albus

Ziel: Das Ziel dieser Darstellung war es, einen aktuellen Überblick über psychosomatisch-psychotherapeutische Aspekte in der Herztransplantationsmedizin zu geben und die Qualität der Studien nach den Cochrane Kriterien zu beurteilen. Ergebnisse: Depressive Patienten haben eine niedrigere Lebenserwartung nach der HTx als nicht depressive Patienten. Patienten mit einer transplantationsbezogenen posttraumatischen Belastungsstörung (PTBS) haben eine signifikant niedrigere Lebenserwartung als Patienten ohne PTBS. Ein erhöhter Body Mass Index nach der HTx erhöht das Risiko, eine chronische Transplantatdysfunktion zu entwickeln. Eine Noncompliance bezüglich der Medikamente vor der HTx sagt ein schlechteres Überleben nach der HTx voraus. Eine Noncompliance bezüglich der Medikation nach der HTx erhöht das Risiko für spätakute Abstoßungsreaktionen und für eine chronische Transplantatdysfunktion. Ein Messintrument zur Abschätzung der Medikamentencompliance ist die Medikamenten-Erfahrungs-Skala für Immunsuppressiva (MESI). Eine internetbasierte psychosoziale Unterstützung kann wahrscheinlich das Outcome der HTx verbessern. Empfehlungen: Die genannten Faktoren müssen berücksichtigt werden. Bei Problemen in einem der Bereiche ist eine konsequente Behandlung zu erfolgen. Ausblick: Es besteht ein Mangel an kontrollierten und randomisierten Studien auf diesem Gebiet. Multizentrische Studiendesigns können helfen, genügend große Fallzahlen zu akquirieren.

10.1055/s-0029-1208244

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Personalisiertes Selbstmanagement Unterstützungsprogramm (P-SUP) für Patient*innen mit Diabetes mellitus Typ 2 und/oder koronarer Herzkrankheit

Das Gesundheitswesen (2021)

H Könnecke Louis J. X. Giesen Jacky G. Goetz Marcus Redaèlli Uwe Konerding

Die Förderung von Selbstmanagement und das Angebot von zusätzlichen Unterstützungsangeboten für Patient*innen mit besonderem Bedarf stellen wichtige Aspekte in der Weiterentwicklung der Disease Management Programme (DMP) für Diabetes Mellitus Typ 2 und koronare Herzkrankheit dar. Ziel von P-SUP ist es, mit einem strukturierten Selbstmanagement-Programms mit gestufter risikostratifizierter Unterstützung die Versorgung zu verbessern und die Anzahl der Krankenhausaufenthalte von Patient*innen beider DMPs zu reduzieren.

10.1055/s-0041-1732053

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Workshop: Corona Pandemie – Herausforderungen nicht nur für die Grundlagenwissenschaften

Das Gesundheitswesen (2021)

Anna Isselhard Maren Töpper Anke Steckelberg Birte Berger‐Höger Frank Vitinius

Einleitung Die Corona Pandemie stellt auch für die laufenden Forschungsprojekte eine Herausforderung dar. Wie ändern sich Prozesse und Interventionen, wenn keine direkten Kontakte mehr möglich sind? Der Haushaltsausschuss des Bundestages hat am 11. März 2020 145 Millionen Euro zusätzlich zur Forschung zum Coronavirus bereitgestellt. Diese Förderbekanntmachung bezieht sich insbesondere auf die Entwicklung von Impfstoffen und Therapien. Darüber hinaus wird es weiteren Forschungsbedarf hinsichtlich der Digitalisierung der Prozesse geben, die aufgegriffen werden sollten.

2019-20 coronavirus outbreak

10.1055/s-0041-1732141

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Up to a Third of Renal Transplant Recipients Have Deficiencies in Cognitive Functioning

Progress in Transplantation (2017)

Lisa Stoessel Katharina Schieber Sabine Jank Sandra Reber Franziska Grundmann

Kidney transplantation is beneficial in improving cognitive abilities in patients with chronic kidney disease; however, there is still uncertainty concerning which cognitive domains benefit and to what extent.In the present study, cognitive functioning of renal transplant recipients was compared to normative data. Sociodemographic and clinical parameters that were associated with low cognitive performance were identified.A total of 109 renal transplant recipients (63% men) participated in the study, with a mean age of 51.8 (standard deviation [SD] = 14.2) years. The cognitive test battery consisted of measurements assessing memory, attention, executive function, reproductive, and deductive ability.In all tests, participants showed mean scores ranging within 1 SD of the population means. However, except for tests measuring memory, the percentage of participants scoring more than 1 SD below normed means was higher than expected in a normal distribution of performance. In certain tests, up to a third of the participants scored below average. Participants with continuous low performance (11%) showed higher age, poorer education, a longer time since transplantation, higher serum levels of urea and creatinine, and were more likely to have a deceased donor allograft.Altough cognitive performance in renal transplant recipients matches normative data and confirms former findings, the amount of patients scoring more than 1 SD below average suggests that there are a considerable number of patients whose cognitive performance in certain domains lies below those of the general population. The identified sociodemographic and biochemical factors might be helpful to identify renal transplant recipients at risk.

Cognitive skill

Cognitive test

10.1177/1526924817731883

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Citations (3)

First results of a prospective study on the predictive value of the German version of the STANFORD INTEGRATED PSYCHOSOCIAL ASSESSMENT FOR TRANSPLANTATION (SIPAT) regarding to psychosocial and somatic outcome parameters in living kidney donation recipients

Journal of Psychosomatic Research (2024)

Frank Vitinius Michaela Henning Christine Kurschat Michael Langenbach W.‐U. Müller

10.1016/j.jpsychores.2024.111785

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Resilience and quality of life in 161 living kidney donors before nephrectomy and in the aftermath of donation: a naturalistic single center study

BMC Nephrology (2015)

Yeşim Erim Yeli̇z Kahraman Frank Vitinius Mingo Beckmann Sylvia Kröncke

Due to the shortage of cadaveric organs, living kidney donation has begun to serve as the most crucial organ pool. Transplant centers have a legitimate interest in expanding the pool of donors. A psychosocial evaluation is established in transplantation centers to prevent donors from possible emotional harm in the aftermath of donation. We explored if the resilience questionnaire is an appropriate measure of the mental stability. To standardize procedures of psychosocial evaluation and to optimize donor recruitment, we present our evaluation protocol and analyze the causes of exclusion from donation. In a naturalistic design, we compared resilience and quality of life in eligible and excluded donors at the time point of donation. Potential living kidney donors (N = 161) participated in the obligatory psychosomatic evaluation. Quality of life (World Health Organization Quality of Life, WHOQOL-Bref) and resilience (Resilience Scale, RS-12) were measured. Three months after nephrectomy donors quality of life was screened in a follow-up. In the evaluation interview donors were classified as eligible (n = 142) or excluded (n = 12). Nonrelated donors (n = 3) were excluded from donation significantly more often (p < .011). Eligible donors (M = 78.42, SD = 10.19) had higher values for resilience than excluded donors (M = 72.7, SD = 8.18, p < .04), who showed values comparable to the norm. In all domains of quality of life, eligible donors had significantly higher values than healthy normals (p < .001). After donation health-related quality of life decreased, but was comparable to the norm. A regression analysis showed that resilience was a significant predictor for all dimensions of quality of life before donation (R2 = 10.2–24.6 %). Post-donation quality of life was significantly correlated with pre-donation resilience scores (p < .05). The resilience score predicts high mental quality of life before and after donation. Therefor it can be implemented as a self-rating instrument to further objectify donor's mental stability. Despite the stressful life event of donation, donor candidates presented high resilience and high levels of quality of life. Therefor our findings support health care providers` intentions to improve living donation. In the group of excluded donors nonrelated persons were overrepresented. Guidelines for the admission of nonrelated donors are currently unclear and need to be optimized.

10.1186/s12882-015-0160-z

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Interval, inspiration-triggered nocturnal odorant application by a novel device: a patient-blinded, randomised crossover, pilot trial on mood and sleep quality of depressed female inpatients

Laryngo-Rhino-Otologie (2018)

Julia Vent Frank Vitinius Hüttenbrink Kb

It has been suggested that certain odorants positively affect mood, but this has not yet been scientifically tested in humans. The aim of the current study was to demonstrate the feasibility of a new odorant applicator and to assess the effects of nocturnal intermittent lavender odorant application on mood, and quality of sleep and dreams in depressed female inpatients.

Crossover study

Affect

Sleep

10.1055/s-0038-1640926

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