Vasopressin (Pitressin) infusion through peripheral veins is a commonly used modality for control of bleeding esophageal varices. In this report we describe the development of infected gangrene at the site of accidental vasopressin infiltration in a patient with diabetes mellitus, cirrhosis and bleeding esophageal varices. Among the explanations for the development of gangrene are: 1. continuous intravenous administration; 2. diabetic peripheral vascular disease; 3. mechanical compression of extravasated fluid in a closed space. No antagonist has been clinically proven to reverse the vasoconstrictive effects of vasopressin.

Gangrene

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Citations (22)

Cutaneous necrosis following peripheral intravenous vasopressin therapy.

PubMed (1982)

Gary P. Wormser L V Kornblee Edward B. Gottfried

Vasopressin infusion through peripheral veins is a commonly used modality for control of bleeding esophageal varices. A cirrhotic patient in whom multiple areas of cutaneous necrosis developed during a course of vasopressin therapy is presented. The involved areas included the infusion sites as well as sites unrelated to infusion but subject to pressure. Patients receiving this form of therapy must be carefully observed for the development of ischemic cutaneous complications.

Infusion therapy

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Citations (15)

Factors predictive of difficult colonoscopy

Gastrointestinal Endoscopy (2001)

Joseph C. Anderson Catherine R. Messina William E. Cohn Edward B. Gottfried Scott Ingber

Diverticular disease

Laxative

Bloating

10.1067/mge.2001.118950

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Citations (239)

Pneumoperitoneum following percutaneous endoscopic gastrostomy

Gastrointestinal Endoscopy (1986)

Edward B. Gottfried Allan B. Plumser Michael R. Clair

Percutaneous endoscopic gastrostomy

10.1016/s0016-5107(86)71919-6

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Citations (125)

The association of remote Streptococcus bovis bacteremia with colonic neoplasia.

PubMed (1982)

I. Friedrich Gary P. Wormser Edward B. Gottfried

We prospectively studied five patients with a remote history of Streptococcus bovis bacteremia who had not previously been evaluated for colonic pathology. This study was prompted by several reports of concomitant neoplasia in patients with recent S. bovis bacteremia. The patients were studied at a mean of 32 months after bacteremia. Despite the absence of other signs or symptoms suggestive of bowel disease, a negative test for occult blood in stool and a negative fecal culture for S. bovis, two patients were found to have neoplastic polyps of the colon. These findings suggest that the risk of colonic neoplasia in patients with remote S. bovis septicemia is similar to that found in patients with recent bacteremia, but evaluation of a larger group of these patients will be necessary to establish this risk.

Streptococcus bovis

Bacteremia

Occult

Concomitant

Fecal occult blood

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Citations (33)