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Daniel Reef

University of North Carolina at Chapel Hill

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Ioannis Mantzaris

Albert Einstein College of Medicine

Noah Kornblum

Montefiore Medical Center

Mendel Goldfinger

Albert Einstein College of Medicine

Kira Gritsman

Albert Einstein College of Medicine

R. Alejandro Sica

Albert Einstein College of Medicine

Ira Braunschweig

Albert Einstein College of Medicine

Nishi Shah

Montefiore Medical Center

Hiba Narvel

Jacobi Medical Center

Fariha Khatun

Montefiore Medical Center

Alyssa de Castro

Albert Einstein College of Medicine

Cooperative Institutions

Albert Einstein College of Medicine

Montefiore Medical Center

The Bronx Defenders

University of North Carolina at Chapel Hill

UNC Lineberger Comprehensive Cancer Center

Montefiore Einstein Comprehensive Cancer Center

Jacobi Medical Center

The University of Texas MD Anderson Cancer Center

Segeberger Kliniken

Yeshiva University

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TCL-150 Outcome of Stem Cell Transplantation in HTLV-1-Associated North American Adult T-Cell Leukemia/Lymphoma

Clinical Lymphoma Myeloma & Leukemia (2022)

Hiba Narvel Abdul Hamid Bazarbachi Daniel Reef Riya Patel Astha Thakkar

Adult T-cell leukemia/lymphoma

10.1016/s2152-2650(22)01573-7

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Poster: TCL-150 Outcome of Stem Cell Transplantation in HTLV-1-Associated North American Adult T-Cell Leukemia/Lymphoma

Clinical Lymphoma Myeloma & Leukemia (2022)

Hiba Narvel Abdul Hamid Bazarbachi Daniel Reef Riya Patel Astha Thakkar

Adult T-cell leukemia/lymphoma

10.1016/s2152-2650(22)01082-5

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Allogeneic but Not Autologous Stem Cell Transplantation Improves Outcome in HTLV-1-Associated North American Adult T-Cell Leukemia/Lymphoma

Abdul Hamid Bazarbachi Daniel Reef Hiba Narvel Riya Patel Rama Al Hamed

Autologous stem-cell transplantation

Adult T-cell leukemia/lymphoma

10.1182/blood-2022-170332

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ABCL-038 HIV Status Affects Access to Autologous Stem Cell Transplant in Primary Central Nervous System B-Cell Lymphomas in a Minority Rich, Ethnically Diverse and Socioeconomically Disadvantaged Population at Montefiore Medical Center/Albert Einstein College of Medicine

Clinical Lymphoma Myeloma & Leukemia (2022)

Hiba Narvel Charan Thej Reddy Vegivinti Daniel Reef Sindhu Vikash Shuai Wang

Autologous stem-cell transplantation

10.1016/s2152-2650(22)01491-4

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Pre-Conditioning Easix Is Associated with Survival after Autologous Hematopoietic Stem Cell Transplant in Mature T-Cell Lymphomas

Daniel Reef John X Wei Alyssa de Castro Felisha Joseph Kailyn Gillick

10.1182/blood-2022-170810

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Poster: ABCL-038 HIV Status Affects Access to Autologous Stem Cell Transplant in Primary Central Nervous System B-Cell Lymphomas in a Minority Rich, Ethnically Diverse and Socioeconomically Disadvantaged Population at Montefiore Medical Center/Albert Einstein College of Medicine

Clinical Lymphoma Myeloma & Leukemia (2022)

Hiba Narvel Charan Thej Reddy Vegivinti Daniel Reef Sindhu Vikash Shuai Wang

Disadvantaged

Ethnically diverse

10.1016/s2152-2650(22)01014-x

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Outcome of Stem Cell Transplantation in HTLV-1-Associated North American Adult T-Cell Leukemia/Lymphoma

Clinical Hematology International (2023)

Abdul Hamid Bazarbachi Daniel Reef Hiba Narvel Riya Patel Rama Al Hamed

Adult T-cell leukemia/lymphoma (ATLL) remains challenging to treat and has dismal outcome. Allogeneic stem-cell transplantation (allo-SCT) has promising results, but data remain scarce. In this single-center retrospective analysis of 100 patients with ATLL from north America (67 acute, 22 lymphomatous), 17 underwent allo-SCT and 5 autologous SCT (ASCT), with a median follow-up of 65 months. Post-transplant 3-years relapse incidence (RI) and non-relapse mortality (NRM) were 51% and 37%, respectively, and 3-year progression-free survival (PFS) and overall survival (OS) were 31% and 35%, respectively. ASCT 1-year RI was 80% compared to 30% in allo-SCT (p = 0.03). After adjusting for immortal-time bias, allo-SCT had significantly improved OS (HR = 0.4, p = 0.01). In exploratory multivariate analysis, patients achieving first complete response and Karnofsky score ≥ 90 had significantly better outcomes, as did Black patients, compared to Hispanics, who had worse outcome. In transplanted patients, 14 died within 2 years, 4 of which ASCT recipients. Our data are the largest ATLL transplant cohort presented to date outside of Japan and Europe. We show that allo-SCT, but not ASCT, is a valid option in select ATLL patients, and can induce long term survival, with 40% of patients alive after more than 5 years.

Autologous stem-cell transplantation

Adult T-cell leukemia/lymphoma

10.1007/s44228-023-00032-y

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Population-Level Outcomes in Solitary Plasmacytoma: A Surveillance, Epidemiology, and End Results (SEER) Study

Daniel Reef Jorge A. Florindez Sascha A. Tuchman Eben I. Lichtman Samuel M. Rubinstein

10.1182/blood-2024-211849

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Effects of Anti-PDGFRβ Therapy Alone or in Combination with VEGF Trap on Corneal Neovascularization (NV) and Pericyte Recruitment in Mice

Investigative Ophthalmology & Visual Science (2014)

Yang Liu Zida Li Daniel Reef Ming Yuan Jingtai Cao

Corneal Neovascularization

Pericyte

Trap (plumbing)

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Autologous Stem Cell Transplantation (ASCT) Improves Survival Outcome in Primary Central Nervous System Lymphoma (PCNSL) in a Minority Rich, Underserved Inner City Population in the Real-World Setting

Hiba Narvel Charan Thej Reddy Vegivinti Sindhu Vikash Abdul Hamid Bazarbachi Shuai Wang

Autologous stem-cell transplantation

Induction chemotherapy

Regimen

10.1182/blood-2022-170703

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Citations (1)