Pei Pei

Peking University

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Gene Therapy Laboratory

Ming Ming

Qingdao University of Technology

Gäng

University of North Sumatra

Jian JIAN

Jiangsu Province Hospital

Zhejiang Lab

Jie Jie

Hangzhou First People's Hospital

Bo Bo

Hunan University

Qing Qing

Tottori University

Wang

National Engineering Research Center of Electromagnetic Radiation Control Materials

Wei

Beth Israel Deaconess Medical Center

Cooperative Institutions

Peking University

201

Chinese Academy of Sciences

173

University of Oxford

143

Chinese Academy of Medical Sciences & Peking Union Medical College

122

Shanghai Jiao Tong University

114

Sun Yat-sen University

104

Zhejiang University

Medical Research Council

Fudan University

Sichuan University

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Analysis on Frequent Flameout of HG- 1025/18.2- YM6 Boiler

电气：英文版 (2005)

Zhang Benyao Yu Yongsheng Cai

Based on reason analyses for frequent flameout of HG-1025/18.2-YM6 boiler in a given power plant after coal quality variation, major factors such as unreasonable burner structure and inappropriate secondary air distribution were discussed in detail. A new mode of secondary air distribution was introduced to optimize the combustion performance, and a lower burner was retrofitted by increasing the relative distance between the primary air fuel rich-lean nozzles and reducing the size of waist air nozzles as well. As a result, the recirculating zone became more stable and the burner's combustion stability was improved.Practical operation shows that the modifications are so effective that the flameout problems caused by instable combustion never occur in operation.

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Advanced practice nurses transitional care promotes anti- coagulation therapy of warfarin in atrial fibrillation patients in South China

岭南心血管病杂志：英文版 (2014)

Lei Lei Zhi-rong Chen Xi Pei Pei

Transitional care

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Construction and Detection of a Novel Type of Recombinant Human rAAV2/2-ND4

眼科学报：英文版 (2013)

Han .Pei Pei Xing Wan Wei-Kun

Purpose:To construct a novel AAV-mediated gene delivery of the human ND4 complex I subunit and to detect its expression level in mitochondria for potential application in gene therapy for Leber’s hereditary optic neuropathy (LHON). Methods:A novel type of normal human ND4 gene was synthesized artificially to contain a mitochondrial targeting sequence that induces the translocation of this gene into mitochondria.This recombinant adeno-associated virus type 2/serotype 2 (rAAV2/2)-mediated NADH dehydrogenase subunit 4 (ND4) gene was constructed, purified, condensed, and amplified by PCR.The physical titer of rAAV2/2-ND4 was determined by slot-blot hybridization using a digoxigeninlabeled H1 probe.Expression of ND4 in mitochondria was evaluated by immunofluorescence. Results: The constructed rAAV2/2-ND4 specifically amplified the target gene band of ND4 and the physical titer of ND4 gene was 1.0×1011 vg/mL,confirming that the recombinant adenovirus vector contained the ND4 target gene. Expression of the ND4 gene was detected in mitochondria by immunofluorescence. Conclusion:A new type of rAAV2/2-ND4 was successfully constructed and may have potential in gene therapy for LHON.

Immunofluorescence

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Radio Interference Characteristic of Ultra-high Voltage AC Transmission Lines by Using Stochastic Modeling

高电压技术 (2013)

He WANGLing Wan Bao-Quan Pei Pei

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A novel carbazole-based fluorescent probe:3,6-Bis-[(N-ethylcarbazole-3-y1)-propene-1-keto]-N-ethylcarbazole

中国化学快报：英文版 (2010)

Hao Li Ling Jun Jun Fen

A novel carbazole-based compound 5,3,6-bis[(N-ethylcarbazole-3-yl)-propene-1-keto]-N-ethylcarbazole has been designed, synthesized and characterized.The absorption and fluorescence spectra in solvents of different polarities prove that the compound has a distinct intramolecular charge transfer character.Compound 5 can be used as a new class of fluorescent probe or biosensor due to its sensitivity to the local microenvironment such as solvent polarity.

Carbazole

Propene

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Effeet of Nano-TiO2 Addition on the Hydration and Hardening Proeess of Stdphoaluminate Cement

武汉理工大学学报：材料科学英文版 (2015)

Ma Baoguo Li Hainan Mei

Hardening (computing)

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A Facile Synthesis and Crystal Structure of 1-Amino-3-（2′-methylphenyl）isoquinolin Hydrochloride

结构化学 (2009)

Zhang Min Min Lv Pei Pei Liping Cao

The title compound (C16H15ClN2) has been synthesized by a facile self-condensation of o-tolunitrile promoted by potassium tert-butanolate in DMPU, and its structure was characterized by 1H NMR, 13C NMR, IR, UV, HRMS and X-ray single-crystal diffraction. The crystal belongs to orthorhombic, space group Pna21 with a = 19.560(3), b = 7.8500(14), c = 18.428(3) , Dc = 1.271 g/cm3, Z = 8, λ = 0.71073, μ(MoKα) = 0.257 mm-1, Mr = 270.75, V = 2829.5(8) 3, Flack para-meter = 0.12(12), F(000) = 1136, the final R = 0.0571 and wR = 0.1445 for 2701 observed reflections with I > 2σ(I). The intermolecular N-H···Cl hydrogen bonds link the molecules into a one-dimensional chain running along axis a.

Orthorhombic crystal system

Crystal (programming language)

Hydrochloride

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Preparation and characterization of AgSt/AgC1 composite grains

中国化学快报：英文版 (2007)

Jing 。 Cao Hai Hai Li -Chien‐Chung Lin

Characterization

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Sonic Hedgehog signaling pathway in primary liver cancer cells

亚太热带医药杂志：英文版 (2014)

Lian-Yi Guo Pei Pei Liu Ying Ying

Objective:To investigate clinical significance of Sonic Hedgehog(SHH)signaling pathway molecular Shh,Smo and Gli2 in primary hepatocellular carcinoma(HCC)tissue.Methods:A total of 30 HCC tissue samples were collected.Protein expression of SHH signaling pathway molecules Shh,Smo and Gli2 in HCC tissues and para-carcinoma tissue were detected by using immimohistochemical method.Cirrhosis and normal liver tissue specimens were observed as control to analyze the expression of SHH signaling pathway molecular Shh,Smo and Glil mRMA in HCC tissues and corresponding para—carcinoma tissues and its relationship with the onset of HCC.Results:There was no expression of Shh,Smo and Gli2 protein in normal liver tissue,while their positive rates were 63.3%,76.79%and 66.7%in HCC tissues,respectively,with a significantly higher expression level than that in the para-carcinoma tissue(P 0.05);Shh and Smo protein was detected in part of cirrhosis with positive expression,but Gli2 protein was not observable in cirrhosis tissues.Conclusions:In HCC tissues,the high expression level of SHH signaling pathway molecules signal peptide(Shh),membrane protein receiptor(Smo)and nuclear transcription molecular(Gli2)can be indicators of the onset of liver cancer.

GLI2

Patched

Smoothened

Liver Cancer

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Global relative input-output sensitivities of the feed-forward loops in genetic networks

Chinese Control Conference (2012)

Pei Pei Jinhu Yu-huan Maciej

Feed forward

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