Junchun Wang

National University of Defense Technology

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Jinjin Guo

Huazhong University of Science and Technology

Yuzhong Zhang

Anhui Normal University

Zilin Guo

China Academy of Chinese Medical Sciences

Junqing Zhao

Shenzhen Technology University

Junjun Zhang

Soochow University

Wenjuan Zhang

Cedars-Sinai Medical Center

Wenjuan Zhang

University of Minnesota

Weiwei Zhao

Baoji University of Arts and Sciences

Xiaowei Han

Nanjing Tech University

Changjing Xu

National University of Defense Technology

Cooperative Institutions

National University of Defense Technology

Hefei University of Technology

Anhui Normal University

Huazhong University of Science and Technology

University of Minnesota

University of Science and Technology Beijing

University of Minnesota System

Nanjing Tech University

Chinese Academy of Sciences

Hefei Institutes of Physical Science

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Horseradish peroxidase functionalized gold nanorods as a label for sensitive electrochemical detection of alpha-fetoprotein antigen

Analytical Biochemistry (2015)

Jinjin Guo Xiaowei Han Junchun Wang Junqing Zhao Zilin Guo

Horseradish peroxidase

Differential pulse voltammetry

Nanorod

Linear range

10.1016/j.ab.2015.09.006

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Citations (42)

Task Allocation Algorthm of Mobile Crowdsensing: Present Research and Trend Analysis

2022 IEEE 10th Joint International Information Technology and Artificial Intelligence Conference (ITAIC) (2022)

Changjing Xu Weiwei Zhao Yang Chen Junchun Wang

The explosive growth of mobile intelligent devices has given birth to the emerging data sensing mode of Mobile crowd sensing (MCS), which mainly relies on the mobile intelligent devices and group intelligence to collect the information of the surrounding environment. Compared with traditional sensor networks, MCS is more suitable for large-scale and real-time sensing scenario due to its low cost, high efficiency. Task allocation is a crucial issue in MCS systems which is intended to achieve a good tradeoff between task quality and task cost. It matches the sensing task with the task participation group, which determines the efficiency of the whole system. In this paper, we introduce the influencing factors, optimization objectives, classification and common implementation algorithms of task allocation model in MCS system. Finally, we summarize challenging issues and prospect the future research direction in this area.

Crowdsensing

Task Analysis

10.1109/itaic54216.2022.9836501

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Citations (2)

Ultrasensitive non enzymatic multiple immunosensor for tumor markers detection by coupling DNA hybridization chain reaction with intercalated molecules

Biosensors and Bioelectronics (2016)

Jinjin Guo Junchun Wang Junjun Zhang Wenjuan Zhang Yuzhong Zhang

DNA–DNA hybridization

Chain reaction

Hybridization probe

10.1016/j.bios.2016.11.048

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Citations (26)

Electrochemical detection of two tumor markers based on functionalized polypyrrole microspheres as immunoprobes

RSC Advances (2016)

Junqing Zhao Zilin Guo Jinjin Guo Junchun Wang Yuzhong Zhang

(A) represents the preparation of the labels and (B) represents the immunosensor preparation and detection principle.

Polypyrrole

10.1039/c6ra01773h

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Citations (15)

Simultaneous electrochemical immunosensing of alpha-fetoprotein and prostate specific antigen using a glassy carbon electrode modified with gold nanoparticle-coated silica nanospheres and decorated with Azure A or ferrocenecarboxylic acid

Microchimica Acta (2015)

Junqing Zhao Zilin Guo Dexiang Feng Jinjin Guo Junchun Wang

Differential pulse voltammetry

Glassy carbon

Nanochemistry

10.1007/s00604-015-1591-8

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Citations (24)

Signal-on electrochemical sensor for the detection of two analytes based on the conformational changes of DNA probes

Analytical Methods (2016)

Junchun Wang Jinjin Guo Junjun Zhang Wenjuan Zhang Yuzhong Zhang

A “signal-on” electrochemical sensor was fabricated for the simultaneous determination of Hg²⁺ and Ag⁺ based on the conformational changes of DNA probes.

SIGNAL (programming language)

10.1039/c6ay02539k

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Citations (7)

Ultrasensitive Multiplexed Immunoassay for Tumor Biomarkers Based on DNA Hybridization Chain Reaction Amplifying Signal

ACS Applied Materials & Interfaces (2016)

Jinjin Guo Junchun Wang Junqing Zhao Zilin Guo Yuzhong Zhang

In this work, a novel electrochemical immunoassay protocol has been reported for simultaneous determination of multiple tumor biomarkers based on DNA hybridization chain reaction (HCR) for signal amplification. Alpha-fetoprotein (AFP) and prostate specific antigen (PSA) were selected as model biomarkers. The immunoassay protocol contained primary antibodies immobilized on gold nanoparticles (Au NPs), secondary antibodies conjugated with DNA concatemer from HCR of primer, auxiliary probe, and signal probe labeled with signal molecules (methyleneblue (MB) and ferrocene (Fc)). In the presence of target biomarkers, the sandwich immunocomplex was formed between the primary antibodies and secondary antibodies bioconjugates carrying numerous signal molecules. As a result, two well-resolved reduction peaks, one was at -0.35 V (corresponding to MB) and other was at 0.33 V (corresponding to Fc; both vs SCE), were obtained in differential pulse voltammetry, and peak currents changed were related to the level of biomarkers. Under optimal conditions, the electrochemical immunoassay exhibited a wide linear response range (0.5 pg mL(-1) to 50 ng mL(-1)) and low detection limits (PSA, 0.17 pg mL(-1); AFP, 0.25 pg mL(-1)) (at S/N = 3). In addition, the immunoassay was evaluated by analyzing simulate human serum sample, and the recoveries obtained were within 99.4-107.6% for PSA and 97.9-108.2% for AFP, indicating the immnuoassay could be applied to the simultaneous detection of AFP and PSA in human serum samples.

Differential pulse voltammetry

10.1021/acsami.6b00756

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Citations (73)

RNA aptamer-based electrochemical aptasensor for C-reactive protein detection using functionalized silica microspheres as immunoprobes

Biosensors and Bioelectronics (2017)

Junchun Wang Jinjin Guo Junjun Zhang Wenjuan Zhang Yuzhong Zhang

Aptamer

10.1016/j.bios.2017.04.014

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Citations (107)

Electrochemical detection of C-reactive protein using Copper nanoparticles and hybridization chain reaction amplifying signal

Analytical Biochemistry (2017)

Junjun Zhang Wenjuan Zhang Jinjin Guo Junchun Wang Yuzhong Zhang

Differential pulse voltammetry

Concatemer

Linear range

10.1016/j.ab.2017.09.017

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Citations (45)

A DNN filtering-based sound source localization method

2022 7th International Conference on Intelligent Computing and Signal Processing (ICSP) (2023)

Qingsong Zhang Hongqing Pan Quanjun Song Junchun Wang

This paper proposes a sound source localization method based on DNN filtering that consists of three parts, namely speech activity detection (VAD), spectral map-based DNN filtering, and sound source localization. First, VAD is used to split the received audio into speech and non-speech segments to reduce computation and reduce the impact of non-speech segments on localization results. Second, filtering of the speech segments is performed to effectively reduce the effect of the low signal-to-noise ratio of the sound source. Lastly, the GCC-phat method is used to supplement the fast localization of sound sources. Experimental results demonstrate that this method has good localization performance under low signal-to-noise ratios.

SIGNAL (programming language)

10.1109/icsp58490.2023.10248493

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Citations (0)