A comparative study has been conducted on the anti-free-radical damage by the vital energy-reinforcing and blood-tonifying methods. The results shows that Sijunzi decoction and Siwu decoction can increase the vitality of SOD, accelerate the elimination of free-radical and inhibit the growth of LPO and MAO-B. This means that both these two methods help to delay senility and the vital energy-reinforcing one is more effective.