Jénifer Martín-González

Universidad de Sevilla

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Juan J. Segura‐Egea

Universidad de Sevilla

Daniel Cabanillas‐Balsera

Universidad de Sevilla

Benito Sánchez-Domínguez

Universidad de Sevilla

L. Castellanos‐Cosano

Universidad de Sevilla

M. C. Jiménez‐Sánchez

Universidad de Sevilla

Victoria Areal‐Quecuty

Universidad de Sevilla

Eugenio Velasco‐Ortega

Universidad de Sevilla

Isabel Crespo-Gallardo

Universidad de Sevilla

José López‐López

Universitat de Barcelona

Paloma Montero‐Miralles

Universidad de Sevilla

Cooperative Institutions

Universidad de Sevilla

Universidade de Santiago de Compostela

Hospital Universitario Virgen del Rocío

Hospital Universitario Virgen Macarena

Universitat de Barcelona

Instituto de Salud Carlos III

Instituto de Biomedicina de Sevilla

Institut d'Investigació Biomédica de Bellvitge

Bellvitge University Hospital

Centro de Investigación Biomédica en Red

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Association between diabetes and nonretention of root filled teeth: a systematic review and meta‐analysis

International Endodontic Journal (2018)

Daniel Cabanillas‐Balsera Jenifer Martín‐González Paloma Montero‐Miralles Benito Sánchez-Domínguez M. C. Jiménez‐Sánchez

Abstract Previous studies have found an association between the outcome of root canal treatment ( RCT ) and diabetic status. This systematic review and meta‐analysis aimed to analyse the potential relationship between diabetes and the occurrence of extracted root filled teeth ( RFT ). The clinical PICO question was as follows: in adult patients with RFT , does the absence or presence of diabetes influence the prevalence of RFT extraction? The key words used in the systematic search were as follows: (Diabetes OR Diabetes Mellitus OR Hyperglycaemia OR Diabetic) AND (Endodontic OR Endodontics OR Endodontic Treatment OR Root Canal Treatment OR Root Canal Preparation OR Root Canal Therapy OR Root Filled Teeth OR Endodontically Treated Teeth) AND (Extraction OR Retention OR Survival OR Success OR Failure OR Outcome). The primary outcome variable was odds ratio ( OR ) for the frequency of extracted RFT in diabetics and healthy subjects. The method of DerSimonian–Laird with random effects was used to calculate the overall OR . Three hundred titles were identified, and three studies achieved the inclusion criteria. Data from 54 936 root canal treatments, 50 301 in nondiabetic control subjects and 4635 in diabetic patients, were analysed. The calculated overall odds ratio ( OR = 2.44; 95% CI = 1.54–3.88; P = 0.0001) implies that diabetics had a significantly higher prevalence of extracted RFT than healthy nondiabetic subjects. The results of available studies indicate a significant relationship between DM and increased frequency of nonretained root filled teeth. Diabetes mellitus should be considered an important preoperative prognostic factor in root canal treatment.

10.1111/iej.13011

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Current Teaching of Endodontics in Dental Schools Around the World: A Systematic Review

Juan J. Segura‐Egea María León‐López Daniel Cabanillas‐Balsera Juan J. Saúco‐Márquez Isabel Crespo-Gallardo

Background. Knowing how Endodontics is currently being taught in undergraduate dentistry studies is of great interest to determine whether new teaching methodologies, new materials and contemporary techniques, as well as new diagnostic and therapeutic criteria, are being incorporated in the teaching of dental students. The aim of this systematic review was to analyze current undergraduate endodontic teaching worldwide. Methods. A literature search was conducted to identify articles about undergraduate endodontic teaching, using the following combinations of keywords: (Endodontics OR endodontology) AND (teaching OR training OR education OR curriculum) AND (undergraduate OR pre-graduate) AND (evaluation OR assessment) AND (dental schools OR dental faculty). Considering that the aim of the review was to analyse the current teaching of Endodontics, the inclusion criteria established were: 1) studies published in the last 10 years, 2) in which those responsible for teaching Endodontics reported some data about the undergraduate training of Endodontics, 3) in dental schools around the world. Results. The search yielded 124 articles related to the teaching of Endodontics. After applying the inclusion criteria, fourteen articles were includes in the systematic review. The data provided were extracted and organized into five sections: 1) General characteristics of teaching Endodontics in the dental curriculum, 2) Teaching methodology in endodontic training, 3) Root canal treatment protocol used in undergraduate endodontic teaching, 4) Use of contemporary materials and technologies in endodontic training, and 5) Assessment methodology in endodontic training. Conclusions. The data found in the published studies show great consistency and, compared with the data found in studies carried out decades ago, allow us to conclude that the quality of current endodontic teaching in dental schools around the world has increased substantially. However, there is stillroom for improvement in some aspects, especially the incorporation of new technologies and materials into the teaching of Endodontics at the undergraduate level. This is the case of magnification, ultrasound and CBCT. The publication by the European Society of Endodontology of the Undergraduate Curriculum Guidelines for Endodontology, with numerous recommendations on the scope of endodontic education, may be the appropriate instrument to continue improving and homogenizing undergraduate teaching of Endodontics throughout the world.

10.20944/preprints202502.0574.v1

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Preventive endodontics: pulp protection using stepwise caries removal procedure

Avances en Odontoestomatología (2011)

L. Castellanos‐Cosano Jenifer Martín‐González C. Calvo-Monroy F.J. López-Frías Eugenio Velasco‐Ortega

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Diabetes mellitus, periapical inflammation and endodontic treatment outcome

Medicina oral, patología oral y cirugía bucal (2011)

Juan J. Segura‐Egea L. Castellanos‐Cosano Guillermo Machuca‐Portillo José López‐López Jenifer Martín‐González

The possible connection between chronic oral inflammatory processes, such as apical periodontitis and periodontal disease (PD), and systemic health is one of the most interesting aspects faced by the medical and dental scientific community. Chronic apical periodontitis shares important characteristics with PD: 1) both are chronic infections of the oral cavity, 2) the Gram-negative anaerobic microbiota found in both diseases is comparable, and 3) in both infectious processes increased local levels of inflammatory mediators may have an impact on systemic levels. One of the systemic disorders linked to PD is diabetes mellitus (DM); is therefore plausible to assume that chronic apical periodontitis and endodontic treatment are also associated with DM. The status of knowledge regarding the relationship between DM and endodontics is reviewed. Upon review, we conclude that there are data in the literature that associate DM with a higher prevalence of periapical lesions, greater size of the osteolityc lesions, greater likelihood of asymptomatic infections and worse prognosis for root filled teeth. The results of some studies suggest that periapical disease may contribute to diabetic metabolic dyscontrol.

Periapical periodontitis

10.4317/medoral.17452

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Effectiveness and clinical implications of the use of topical antibiotics in regenerative endodontic procedures: a review

International Endodontic Journal (2018)

Paloma Montero‐Miralles Jenifer Martín‐González Óscar Alonso-Ezpeleta M. C. Jiménez‐Sánchez Eugenio Velasco‐Ortega

Regenerative endodontic procedures (REPs) are biologically based procedures planned to replace damaged tissues, including dentinee and root structures, as well as cells of the pulp-dentine complex. Effective sterilization of the root canal is essential in REPs, and antibiotics have been widely used to disinfect root canals. The aim of this paper was to review the scientific literature on (i) Effectiveness of antibiotics used in REPs against bacteria implicated in endodontic disease; (ii) Scientific evidence supporting the use of topical antibiotics in REPs; (iii) Clinical implications of the use of antibiotics in REPs and the possible side effects; (iv) Effect of antibiotics on dental pulp stem cells; and (v) Ongoing research on the use of antibiotics in REPs. Antibiotics used in REPs are effective against bacteria implicated in endodontic infections. Triple antibiotic pastes with minocycline attain complete disinfection of immature teeth with necrotic pulps, without affecting SCAP. Experimental studies carried out in dogs support the use of antibiotics in REPs. Clinical studies report high success rates of RET using antibiotics as intracanal dressings. However, tooth discolouration is an important side effect of the use of TAP. An antibiotic paste containing only metronidazole and ciprofloxacin could be a good alternative to the use of TAP. The use of antibiotic-containing scaffolds or clindamycin-modified triple antibiotic (metronidazole, ciprofloxacin and clindamycin) polymer could be a biologically safe antimicrobial drug delivery system in REPs.

10.1111/iej.12913

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Predictors of periapical bone healing associated with teeth having large periapical lesions following nonsurgical root canal treatment or retreatment: A cone beam computed tomography‐based retrospective study

International Endodontic Journal (2023)

Carolina Mosquera‐Barreiro Manuel Ruíz‐Piñón Francesc Abella Venkateshbabu Nagendrababu Thilla Sekar Vinothkumar

Abstract Aim Several factors influence the condition of the periapical tissues associated with root filled teeth. The primary objective of this study was to retrospectively evaluate the extent and speed of bone healing of large periapical lesions associated with nonsurgical root canal treatment or retreatment. The secondary objective was to analyse the relationship between the time to complete healing when analysed using cone beam computed tomography (CBCT) and other possible predictors that affect healing. Methodology Seventy‐nine patients were treated during the years 2013–2020 with large periapical lesions of endodontic origin (10–15 mm) as observed on intraoral periapical radiographs (IOPAR) were included. IOPAR and CBCT were available before treatment and during the follow‐up (IOPAR every 6 months and CBCT every 12 months). The volume of periapical lesions was calculated by OsiriX Lite software. Variables such as initial volume of the lesion, age, gender, type of treatment or type of root canal filling were compared to identify the differences between healed and unhealed lesions. Pearson's Chi‐square test was used for categorical variables, the t‐test for age and the Wilcoxon test for initial volume of the lesion. The association between time to healing and the variables was assessed using univariate analysis and multivariate analysis. The Wilcoxon test was used to observe the association of healing time with categorical variables and the correlation index was measured with the quantitative variables. Results Of the 79 cases analysed, 60 lesions (76%) were completely healed as verified by CBCT in a mean healing time of 19 months, of which 60% healed fully between 12 and 18 months. Increase in age of patient and larger initial volume of the lesion were associated with a significantly longer healing time ( p < .001). Gender, filling material and type of treatment did not have a significant effect on the healing process ( p > .05). Conclusions Clinicians should be aware that periapical lesions in older patients and larger areas of bone loss take longer to heal. CBCT monitoring of large periapical lesions is critical and it can help clinicians in the decision‐making process.

Endodontic retreatment

Univariate analysis

10.1111/iej.13993

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Ciclo de mejora en el aula aplicado en una asignatura clínica con pacientes del Postgrado en Odontología

JORNADAS DE FORMACIÓN E INNOVACIÓN DOCENTE DEL PROFESORADO (2020)

Jenifer Martín‐González

10.12795/9788447231003.045

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Systemic Health and Endodontics

Juan J. Segura‐Egea Jenifer Martín‐González

Periodontal fiber

Pulpitis

Focal infection theory

10.1002/9781119553939.ch7

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Influencias psicológicas al envejecer y adaptación a la institucionalización: revisión sistemática para mejorar el cuidado de enfermería

Luis Jesús Martín González Almudena Dolores Alférez Maldonado Francisco Luis Montes Galdeano Jenifer Martín‐González Isabel María Jodar López

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Association between dental anxiety and intraoperative pain during root canal treatment: a cross‐sectional study

International Endodontic Journal (2019)

M. Murillo‐Benítez Jenifer Martín‐González M. C. Jiménez‐Sánchez Daniel Cabanillas‐Balsera Eugenio Velasco‐Ortega

To investigate whether dental anxiety influences the intraoperative pain felt by patients during root canal treatment.In a cross-sectional design, 180 patients (90 men and 90 women) were included. Pre-operative anxiety levels were assessed using the short-form Dental Anxiety Inventory (S-DAI). Pain during root canal treatment was evaluated using a 10-cm visual analogue scale (VAS) that ranked the level of pain between 'Absence of pain' and 'Unbearable pain'. The minimal sample size was determined using the software of the National Center for Advancing Translational Sciences (NIH, UK). Multivariate logistic regression analysis was used to identify relationships between variables.Mean pain level during root canal treatment was 2.2 ± 2.1. The mean anxiety S-DAI score was 27.2 ± 12.5. Fifty percent of men had mild anxiety levels, while in 70% of women anxiety was moderate or high (P = 0.017). Anxiety correlated positively with intraoperative pain (R = 0.406). Multivariate logistic regression analysis revealed that anxiety was significantly associated with intraoperative pain felt by patients (OR = 4.0; 95% C.I. = 1.7-9.3; P = 0.001).Anxious patients were more than twice as likely to feel moderate or intense intraoperative pain during root canal treatment. To know the patient´s degree of anxiety could help the dentist to decide whether to use anxiolytic premedication and/or supplemental local anaesthesia to assure better control of pain during root canal treatment.

Cross-sectional study

Association (psychology)

10.1111/iej.13245

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Citations (34)