Background: Cardio respiratory fitness in terms of maximum oxygen uptake (VO2 max) reflects the physical fitness of a person. VO2max determines the capacity of an individual to perform sustained exercise. The present study is to assess and compare the cardiorespiratory fitness in terms of VO2 max between trained and untrained subjects.
Materials and Methods: This cross-sectional study was conducted on 30 young adult males undergoing physical training for more than 3 months to join British army and age-sex matched 30 non-trained controls. VO2max was estimated indirectly by following the protocol of Queen’s College Step Test (QCT) method.
Results: VO₂ max was found significantly higher in the trained males as compared to non-trained group (68.91± 4.42 vs. 50.31±4.80; p=0.02). On comparison of VO₂ max of our subjects with the standard VO₂ max classification, our trained and non-trained groups fitted into the category of high and average on cardiorespiratory fitness scale respectively.
Conclusion: Physical training improves cardio respiratory fitness by increasing VO₂ max.
Background Vitamin B12 deficiency is commonly observed in hypothyroidism and autoimmune thyroiditis. Low vitamin B12 can disrupt thyroid function. Though the prevalence of this deficiency has been documented in various regions of Nepal, studies in Eastern Nepal are limited. The objective of this study was to assess the percentage distribution of vitamin B12 deficiency among adults visiting the tertiary health care centre in Eastern Nepal and to find out the effect of vitamin B12 deficiency on thyroid function test. Methods This study, conducted at Nobel Medical College from January 2022 to December 2023, was cross-sectional in design and included 379 patients. Subjects underwent general health check-ups, including Vitamin B12 and thyroid function tests. Descriptive analysis was performed, and Pearson’s correlation assessed the relationship between vitamin B12 levels and thyroid hormones. Independent t-tests compared hormone levels between groups. P value < 0.05 was considered as statistically significant. Results The vitamin B12 status distribution was as follows: 62.5% normal (>300pg/ml), 18.2% borderline deficient (200-300pg/ml), and 19.3% deficient (<200pg/ml). Prevalence was higher among females. Group II subjects (vitamin B12 <300pg/dl) had significantly lower mean free triiodothyronine (FT3) levels (2.82±0.742 vs. 3.14±0.49 pg/mL, p=0.003) and higher mean thyroid stimulating hormone (TSH) levels (4.69±3.56 vs. 2.55±1.47 mIU/L, p<0.001) compared to group I (B12 >300pg/ml). Vitamin B12 showed a negative correlation with TSH (p=0.013). Conclusion The study indicates a decrease in FT3 levels and an increase in TSH levels among those with vitamin B12 deficiency or borderline cases
Background: This study aimed to investigate heart rate variability among traffic police officers and compare these parameters between exercising and non-exercising groups. Heart rate variability is an important marker of cardiac autonomic function. Understanding the impact of exercise on heart rate variability among traffic police officers can provide valuable insights into strategies for improving their cardiovascular well-being. Materials and Methods: This comparative correctional study was conducted among forty-two healthy traffic police officers. The participants were divided into exercising and non-exercising groups based on their physical activity levels. Heart rate variability was measured using standard technique. Data was analysed using Microsoft Excel and SPSS version 16. The heart rate variability values were non parametric. So, data were expressed as median interquartile range and comparison between two groups was done with Mann-Whitney U test. p<0.05 was considered significant. Results: The results revealed that a higher proportion of traffic police officers were in the exercising group. Heart rate variability analysis showed significantly higher median values of RMSSD (58.42 ms vs. 41.30 ms), NN50 (80.00 vs. 24.00), pNN50% (36.56% vs. 11.820%) and HF power (1079.40 ms² vs. 368.000 ms²) in the exercising group. Additionally, the exercising group exhibited a lower LF/HF ratio (0.61 vs. 1.60). Although not statistically significant, heart rate was less in exercising group (73.61±6.93bpmvs. 72.93± 7.79bpm). Conclusion: The study suggests that even with prolonged workplace posture, exercise among traffic police can have higher heart rate variability and parasympathetic dominance, a positive indicator for cardiovascular health.
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