MR of the brain was performed in eight patients (mean age, 14.9 years) with osteogenic sarcoma during or after IV treatment with high-dose methotrexate. MR detected brain abnormalities in four patients, three of whom had concomitant neurologic dysfunction. Pathologic findings demonstrated on MR were (1) chronic brain edema, demonstrable over a period of 3-14 months (proved by autopsy in one patient); (2) multifocal white matter necrosis; and (3) deep brain atrophy. MR appears to be valuable in the detection of abnormalities induced by treatment with high-dose methotrexate.

Concomitant

10.2214/ajr.153.6.1283

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Citations (37)

Computed tomographic diagnosis of left superior vena cava and absence of the azygos vein: Case report

CardioVascular and Interventional Radiology (1990)

P Kullnig G. Melzer Klaus A. Hausegger R. Einspieler

Azygos vein

Thorax (insect anatomy)

Vascular anomaly

Vena cava

10.1007/bf02576939

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Citations (12)

Computer guided, topographical concordant synopsis of MRI and ECT with Tc99 n Anti-CEA AB in the verification of recurrences of rectal cancer - method and first experiences.

L Kronberger R. Einspieler G. Ranner Roberto Nicoletti F. Ebner

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[MR study of bone marrow changes of the spine following radiotherapy].

PubMed (1990)

I Starz R. Einspieler H. Poschauko F. Ebner K. Arian-Schad

MR examinations of bone marrow variations in the spine after radiotherapy were performed on 24 patients in the thoracic and lumbar vertebral column. The actinically affected bone marrow showed a characteristic increase of signal intensity in T1-weighted sequences in the sagittal plane, due to conversion of red marrow to fatty marrow. The dose in the well-defined radiation areas was between 28 and 70 Gray (Gy). The lowest dose, applied to the bone-marrow bordering on the defined radiation areas, where we still could find an increase of signal intensity, was below 2.6 to 5 Gy. MR imaging was performed between 6 and 9 month after radiotherapy.

Vertebral column

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Citations (1)

Imaging of uterine cervical carcinoma on MRI (In German)

Clinical Imaging (1990)

R. Einspieler Franz Ebner Hilmar Hoffmann

10.1016/0899-7071(90)90103-i

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