Harilakshmi Jayachandran

National University of Singapore

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Kok‐Peng Ang

National University of Singapore

S.‐F. TAN

Fourth Affiliated Hospital of Guangxi Medical University

Sau‐Fun Tan

Cancer Australia

K. P. Ang

National University of Singapore

Gee‐Fung How

Singapore General Hospital

M. P. SAMMES

University of Hong Kong

Yoke-Fan Fong

Sau-Fun Tan

National University of Singapore

Y.‐F. FONG

National University of Singapore

Cooperative Institutions

National University of Singapore

Fourth Affiliated Hospital of Guangxi Medical University

Singapore General Hospital

Institute of Molecular and Cell Biology

University of Hong Kong

University of Florida

Cancer Australia

Instituto Valenciano de la Edificación

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

ChemInform Abstract: Substituent Effects in 1H and 13C NMR Correlations of Chemical Shifts in para‐Substituted 5‐Arylmethylenehydantoins

ChemInform (1987)

S.‐F. TAN K. P. Ang Harilakshmi Jayachandran Y.‐F. FONG

Chemical shift

10.1002/chin.198748039

Cite

Citations (0)

Mixed-ligand cobalt(III) complexes derived from bis(dehydroacetato)ethylenediimine

Transition Metal Chemistry (1986)

Sau-Fun Tan Kok‐Peng Ang Harilakshmi Jayachandran

Organometallic Chemistry

10.1007/bf01386873

Cite

Citations (3)

Ionization constants of 5-arylmethylenehydantoins in 80%(w/w) dimethyl sulphoxide–water at 25 °C

Journal of the Chemical Society. Perkin transactions II (1988)

Sau‐Fun Tan Kok‐Peng Ang Yoke-Fan Fong Harilakshmi Jayachandran

The pK values of (Z)-5-arylmethylenehydrantoins, (Z)-5-arylmethylene-3-methylhydantoins, and (Z)- and (E)-5-arylmethylene-1-methylhydantoins with various para-substituents in the phenyl ring have been measured. The effects of structure and stereochemistry on acidity are discussed. For each series, a good linear correlation is obtained between the pK values and Hammett constants σ and σ– in spite of the considerable distance of the site of deprotonation from the phenyl ring. The ρ values show that substituent effects are significantly greater on the acidity of N(1)–H than on that of N(3)–H, and are also greater for the E- than the Z-isomers of the 5-arylmethylene-1-methylhydantoins.

Linear correlation

Linear relationship

10.1039/p29880000473

Cite

Citations (12)

ChemInform Abstract: IONIZATION CONSTANTS OF SOME HYDROXYPYRONES IN WATER AND IN 80% (W/W) DIMETHYL SULFOXIDE‐WATER AT 25°

Chemischer Informationsdienst (1983)

S.‐F. TAN K. P. Ang Harilakshmi Jayachandran

10.1002/chin.198330087

Cite

Citations (0)

Unsymmetrical bis-Schiff bases derived from ethylenediamine, dehydroacetic acid and another aldehyde/Ketone and the preparation and characterisation of their copper(II) and nickel(II) complexes

Transition Metal Chemistry (1989)

Sau-Fun Tan Kok‐Peng Ang Harilakshmi Jayachandran

Dehydroacetic acid

Ethylene diamine

Organometallic Chemistry

10.1007/bf01092595

Cite

Citations (0)

Effects of 5-acyl substituents on some properties of pyran-2,4-diones

Journal of the Chemical Society. Perkin transactions II (1984)

Sau‐Fun Tan Kok‐Peng Ang Harilakshmi Jayachandran M. P. SAMMES

The effects of 5-acyl substituents on the tautomerism of pyran-2,4-diones are revealed by comparison of the u.v.,i.r., 1H, and 13C n.m.r. spectral properties of 5-acetyl-6-methyl-,5-acetyl-6-phenyl-,5-benzoyl-6-methyl-, and 3,5-diacetyl-6-methyl-pyran-2,4-diones (3)–(6), with those of 6-methyl-(1) and 3-acetyl-6-methyl-pyran-2,4-done (2). The differences in the behaviour of the 5-acyl and 3-acyl derivatives towards primary amines are also discussed. Compound (6) reacts with aniline to form 5-acetyl-2,6-dimethyl-1-phenyl-4-oxopyridine-3-carboxylic acid (7).

Pyran

10.1039/p29840001317

Cite

Citations (9)

ChemInform Abstract: IONIZATION CONSTANTS OF SOME SCHIFF′S BASES IN 80% (W/W) DIMETHYL SULFOXIDE‐WATER SOLVENT AT 25°

Chemischer Informationsdienst (1983)

S.‐F. TAN K. P. Ang Harilakshmi Jayachandran

10.1002/chin.198342096

Cite

Citations (0)

ChemInform Abstract: EFFECTS OF 5‐ACYL SUBSTITUENTS ON SOME PROPERTIES OF PYRAN‐2,4‐DIONES

Chemischer Informationsdienst (1984)

S.‐F. TAN K. P. Ang Harilakshmi Jayachandran M. P. SAMMES

Pyran

10.1002/chin.198447093

Cite

Citations (0)

ChemInform Abstract: Ionization Constants of 5‐Arylmethylenehydantoins in 80% (w/w) DMSO‐Water at 25 °C.

ChemInform (1988)

S.‐F. TAN K. P. Ang Y.‐F. FONG Harilakshmi Jayachandran

10.1002/chin.198830074

Cite

Citations (0)

A spectrophotometric study of the tautomeric monoanions of (Z)-5-arylmethylenehydantoins

Journal of the Chemical Society. Perkin transactions II (1989)

Sau‐Fun Tan Kok‐Peng Ang Gee‐Fung How Harilakshmi Jayachandran

First ionization of (Z)-5-arylmethylenehydantoins in aqueous dimethyl sulphoxide yields a tautomeric mixture of monoanions by deprotonation at N-1 or N-3. By using appropriate 3-methyl and 1-methyl derivatives as models, the equilibrium proportions of the monoanions of the N-unsubstituted compounds have been estimated from the electronic spectra. The percentage of the N-1 anion increases with electron-withdrawing substituents in the benzene ring and with increasing concentration of dimethyl sulphoxide in the solvent mixture.

10.1039/p29890000499

Cite

Citations (5)