Gianna Dipalma

University of Bari Aldo Moro

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Francesco Inchingolo

University of Bari Aldo Moro

276

Angelo Michele Inchingolo

University of Bari Aldo Moro

182

Alessio Danilo Inchingolo

University of Bari Aldo Moro

181

Giuseppina Malcangi

University of Bari Aldo Moro

101

Andrea Palermo

University of Salento

Antonio Mancini

University of Bari Aldo Moro

Assunta Patano

University of Bari Aldo Moro

Andrea Ballini

University of Campania "Luigi Vanvitelli"

Antônio Scarano

University of Chieti-Pescara

Ioana Roxana Bordea

Iuliu Hațieganu University of Medicine and Pharmacy

Cooperative Institutions

University of Bari Aldo Moro

261

University of Naples Federico II

University of Milan

University of Foggia

Sapienza University of Rome

University of Campania "Luigi Vanvitelli"

Istituti di Ricovero e Cura a Carattere Scientifico

University of Chieti-Pescara

Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari

Azienda Ospedaliera S.Giuseppe Moscati

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Potential of Graphene-Functionalized Titanium Surfaces for Dental Implantology: Systematic Review

Coatings (2023)

Angelo Michele Inchingolo Giuseppina Malcangi Alessio Danilo Inchingolo Antonio Mancini Giulia Palmieri

Titanium is the most frequently employed material in implantology, because of its high degree of biocompatibility. The properties of materials are crucial for osteointegration; therefore, great effort from researchers has been devoted to improving the capabilities of titanium implant surfaces. In this context, graphene oxide represents a promising nanomaterial because of its exceptional physical and chemical qualities. Many authors in recent years have concentrated their research on the use of graphene in biomedical applications such as tissue engineering, antimicrobial materials, and implants. According to recent studies, graphene coatings may considerably increase osteogenic differentiation of bone marrow mesenchymal stem cells in vitro by the regulation of FAK/P38 signaling pathway, and can encourage the osteointegration of dental implants in vivo. However, further studies, especially on human subjects, are necessary to validate these potential applications. The aim of this work was to evaluate the effects of graphene on bone metabolism and the advantages of its use in implantology. A systematic review of literature was performed on PubMed, Web of Science and Scopus databases, and the articles investigating the role of graphene to functionalize dental implant surfaces and his interactions with the host tissue were analyzed.

Biocompatibility

10.3390/coatings13040725

Cite

Citations (15)

ACCURATEZZA DIAGNOSTICA DELLO STAGING DELL’ HCC NEI PAZIENTI CON CIRROSI: LA LEZIONE DEI TRAPIANTI DI FEGATO

L. Lupo A Gentile A. Stabile Ianora M. Rendina Pasquale Ricci

Source

Cite

Citations (0)

Paediatric dental trauma: insights from epidemiological studies and management recommendations

BMC Oral Health (2025)

Alessandra Laforgia Angelo Michele Inchingolo Francesco Inchingolo Roberta Sardano Irma Trilli

Abstract Dental trauma is common in all age groups, although, epidemiologically, it is more common in children with studies that indicate that 15% of preschoolers and 20–25% of school-age children experience it. These injuries, which frequently call for immediate attention, can affect the hard tissues and supporting components of the teeth, and, because dental damage in deciduous teeth occurs frequently and affects speech, nutrition, and oral development, it is particularly worrying. After searching three databases, Scopus, Web of Science (WoS), and PubMed, and removing duplicates, 3,630 articles were screened, and 12 publications were included in the qualitative analysis. Due to their busy lifestyles, children are particularly susceptible to oral trauma and in certain areas and lower socioeconomic groups, the incidence is higher. From little fractures in the enamel to serious dislocations and avulsions, injuries vary and must be treated promptly in order to avoid consequences and to prevent long-term issues. Furthermore, a conservative treatment strategy is recommended to preserve tooth vitality and prevent extractions. Reducing the occurrence of dental injuries requires the implementation of preventive measures including mouthguard use and educational campaigns. In summary, this review emphasizes the importance of early diagnosis, immediate management, and long-term care, by synthesizing existing knowledge on the prevalence, types, management, complications, and prevention of dental trauma in deciduous teeth. Finally, it’s important to underscore the need for continued research to refine treatment approaches.

Dental trauma

Mouthguard

Vitality

10.1186/s12903-024-05222-5

Cite

Citations (0)

Analysis of Risk Factors of Oral Cancer and Periodontitis from a Sex- and Gender-Related Perspective: Gender Dentistry

Applied Sciences (2022)

Federica Di Spirito Alessandra Amato Antonio Romano Gianna Dipalma Edit Xhajanka

Gender-specific medicine studies how sexual biology and gender-related cultural and behavioral differences may influence a person’s health and considers the differences in clinical features, prevention, therapies, prognosis, and psycho-social aspects of diseases with different impacts on women and men. The present work summarizes the main differential impact each risk factor for oral cancer and periodontitis has according to biological sex- and gender-oriented differences. It resulted in differences in epidemiology and the weight of various healthy determinants that may influence the incidence and prognosis of oral cancer and periodontitis. It is desirable to change the methodology of scientific studies with a higher focus on the weight that sexual variables may have on the well-being or the probability of getting ill of each person, thus promoting the development and diffusion of personalized gender dentistry.

10.3390/app12189135

Cite

Citations (11)

The Association Between Temporomandibular Disorders and Tinnitus: Evidence and Therapeutic Perspectives from a Systematic Review

Journal of Clinical Medicine (2025)

Gianna Dipalma Alessio Danilo Inchingolo Carmela Pezzolla Roberta Sardano Irma Trilli

Background/Objectives: Tinnitus, often described as a ringing in the ears, affects a significant portion of the population, varying in perception and severity. Methods: This systematic review investigates the correlation between tinnitus and temporomandibular joint disorders (TMDs) within a PRISMA-compliant framework, ensuring methodological transparency and rigor. Using databases, such as PubMed, Scopus, and Web of Science, we analyzed studies from the past decade to evaluate clinical and observational evidence. Results: A significant association between TMD and tinnitus was found, with somatosensory and neuroplastic mechanisms contributing to this relationship. Key therapeutic approaches identified include manual therapy and multidisciplinary treatments, demonstrating potential clinical efficacy. Conclusions: However, the available evidence remains inconsistent, emphasizing the need for further research with standardized methodologies to improve understanding and refine therapeutic strategies. This review provides a foundation for future studies aiming to enhance tinnitus management by addressing underlying TMD-related mechanisms.

10.3390/jcm14030881

Cite

Citations (0)

Periodontal disease and bone pathogenesis: the crosstalk between cytokines and porphyromonas gingivalis.

Journal of Biological Regulators and Homeostatic Agents/Journal of Biological Regulators & Homeostatic Agents (2015)

Andrea Ballini Stefania Cantore Davide Farronato Nunzio Cirulli Francesco Inchingolo

Periodontal disease is the most frequent cause of tooth loss among adults. It is defined as a plaque-induced inflammation of the periodontal tissues that results in a loss of support of the affected teeth. This process is characterized by destruction of the periodontal attachment apparatus, increased bone resorption with loss of crestal alveolar bone, apical migration of the epithelial attachment, and formation of periodontal pockets. Although the presence of periodontal pathogens such as Porphyromonas gingivalis is a prerequisite, the progression of periodontal disease is dependent on the host response to pathogenic bacteria that colonize the tooth surface. Nowadays, a growing body of literature has accumulated to investigate the association between bone diseases, periodontal pathogens and periodontal diseases. The integration of pathogen-associated molecular patterns from microorganisms with their surface receptors in the immune cells, induces the production of several cytokines and chemokines that present either a pro- and/or anti-inflammatory role and the activation of mechanisms of controlling this and the related disease, such as osteoporosis and rheumatoid arthritis. This review focuses on the evidence and significance of bone host cell invasion by Porphyromonas gingivalis in the pathogenesis of bone disorders, as well as the different lines of evidence supporting the role of cytokines in bone diseases.

Pathogenesis

Periodontal pathogen

Tooth surface

Bone remodeling

Tooth loss

Source

Cite

Citations (48)

Do intramedullary implants improve survival in elderly patients with trochanteric fractures? A retrospective study.

PubMed (2015)

D Vermesan Radu Prejbeanu Dan V. Poenaru Horia Alexandru Petrescu Enya Marie D. Apostol

There is currently no consensus regarding superiority of the intramedullary fixation over the sliding hip screw. Regional variation remains high and not backed up by solid evidence. Given these premises we aimed to analyze weather implant preference can influence the postoperative survival. Secondary objectives were determining the trend for implant choice and confounding factors associated with intramedullary nails compared to sliding hip screws.Retrospective data was obtained from patient charts with the main diagnosis of extracapsular/ trochanteric fractures, corresponding to ICD S72.1 codes. Between 2008-2012, 441 patients underwent osteosynthesis with a dynamic hip screw and 155 with intramedullary nail respectively. The living status was determined by comparing the patient identification number against the national population evidence records.The lifetable shows similar survival for both implants over the 5 year period. The yearly mortality was 19.4% for the dynamic hip screw and 21.8% for the intramedullary implant respectively, even though the later were used predominantly in older patients. This age difference is significant according to both parametric and non-parametric tests whereas duration of hospital stay are similar. We found a clear increase in the proportion of intramedullary implants, for a total of 11.2% over the 5 year period. There is no difference for the one year mortality and overall survival between sliding screw plates and intramedullary constructs.A clear increase in the use of intramedullary implants for trochanteric fractures was observed. This is even more apparent for older ages, presumably due to an higher surgeon confidence with the biomechanical stability of the intramedullary constructs.

Implant Failure

Osteosynthesis

10.7417/ct.2015.1844

Cite

Citations (7)

Guided Bone Regeneration: CGF and PRF Combined With Various Types of Scaffolds—A Systematic Review

International Journal of Dentistry (2024)

Francesco Inchingolo Angelo Michele Inchingolo G Latini Elisabetta de Ruvo Merigrazia Campanelli

Bone regeneration plays a pivotal role in modern oral surgery, particularly in facilitating successful implant-prosthetic rehabilitation. This systematic review explores the regenerative potential of growth factors, such as platelet-rich fibrin (PRF) and concentrated growth factors (CGFs), when combined with various types of scaffolds in bone augmentation procedures, including guided bone regeneration, split crest, sinus lift (SL), and alveolar ridge preservation.

10.1155/ijod/4990295

Cite

Citations (0)

Diagnosis and Orthodontic Treatment of Obstructive Sleep Apnea Syndrome Children—A Systematic Review

Diagnostics (2024)

Kenan Ferati Arbëresha Bexheti‐Ferati Andrea Palermo Carmen Pezzolla Irma Trilli

Obstructive sleep apnea syndrome (OSAS) is a respiratory illness that is associated with recurrent episodes of either partial or full obstruction of the upper airways, or apnea, among other sleep disorders. This study aims to analyze, through a literature review, whether orthodontic treatment can be a good treatment strategy for this type of disorder. We performed a database search on Scopus, Web of Science, and Pubmed with the keywords OSA(S) and orthodontics to select the papers under evaluation. The criteria for inclusion were articles related to OSA(S) children undergoing an orthodontic treatment and clinical studies or case series, excluding systematic reviews, narrative reviews, meta-analyses, adult studies, animal models, and in vitro studies. The screening phase ended with the selection of 16 publications for this work. RME, or rapid maxillary expansion, turned out to be the preferred orthodontic treatment in cases of pediatric OSAS. The goal of this orthodontic procedure is to increase the hard palate’s transverse diameter by reopening the mid-palatal suture. Children with maxillary contraction and dental malocclusion typically undergo such a procedure and have excellent results. However, OSAS is a multifactorial disorder; it does not seem related to the morphology of the oral cavity, and therefore, it is not always possible to cope with this problem exclusively through orthodontic treatment.

Narrative review

Oral appliance

10.3390/diagnostics14030289

Cite

Citations (7)

Coronavirus (SARS-CoV-2) Pandemic: Future Challenges for Dental Practitioners

Microorganisms (2020)

Ioana Roxana Bordea Edit Xhajanka Sebastian Candrea Simion Bran Florin Onișor

In the context of the SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) pandemic, the medical system has been subjected to many changes. Face-to-face treatments have been suspended for a period of time. After the lockdown, dentists have to be aware of the modalities to protect themselves and their patients in order not to get infected. Dental practitioners are potentially exposed to a high degree of contamination with SARS-CoV-2 while performing dental procedures that produce aerosols. It should also be noted that the airways, namely the oral cavity and nostrils, are the access pathways for SARS-CoV-2. In order to protect themselves and their patients, they have to use full personal protective equipment. Relevant data regarding this pandemic are under evaluation and are still under test. In this article, we made a synthesis about the way in which SARS-CoV-2 spreads, how to diagnose a novel corona virus infection, what the possible treatments are, and which protective personal equipment we can use to stop its spreading.

Pandemic

Personal Protective Equipment

Face shield

Coronavirus

Modalities

2019-20 coronavirus outbreak

10.3390/microorganisms8111704

Cite

Citations (44)