Ricardo Romiti

Universidade de São Paulo

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Neusa Yuriko Sakai Valente

Hospital do Servidor Público Estadual

Marcelo Arnone

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

Alessandra Anzai

Hospital Universitário da Universidade de São Paulo

Fernando Valenzuela

University of Chile

Aline Donati

Hospital do Servidor Público Municipal

André Vicente Esteves de Carvalho

Hospital Moinhos de Vento

Thomas Jansen

Aberystwyth University

C.E.M. Griffiths

University of Manchester

Isabella Doche

Hospital Universitário da Universidade de São Paulo

L. Puig

Universitat Autònoma de Barcelona

Cooperative Institutions

Sociedad Española de Reumatología

252

Mettler-Toledo (United Kingdom)

250

Maestro (Sweden)

247

Universidade de São Paulo

222

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

171

Universidade Federal de São Paulo

John Wiley & Sons (United States)

Oxfam

John Wiley & Sons (United Kingdom)

Hudson Institute

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Complete Closure by Purse-String Suture After Mohs Micrographic Surgery on Thin, Sun-Damaged Skin

Dermatologic Surgery (2002)

Ricardo Romiti Henry W. Randle

The purse-string suture technique is useful for partial closure of surgical defects.We demonstrated that 100% closure can often be obtained on surgical defects of the thin skin on the upper extremities.Standard purse-string suture techniques were used to close surgical defects on the upper extremities.100% closure of surgical defects on upper extremities was demonstrated.Purse-string suture technique is useful for repairs of surgical defects on the upper extremities when the skin is very thin but not recommended when the skin is thick.

Closure (psychology)

Mohs surgery

10.1046/j.1524-4725.2002.t01-1-02091.x

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Citations (16)

Consenso Brasileiro de Psoríase 2020 e Algoritmo de Tratamento da Sociedade Brasileira de Dermatologia

Ricardo Romiti André Vicente Esteves de Carvalho Gleison Vieira Duarte

10.1016/j.abdp.2021.09.013

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Sustained response with ixekizumab treatment of moderate-to-severe psoriasis with scalp involvement: results from three phase 3 trials (UNCOVER-1, UNCOVER-2, UNCOVER-3)

Journal of Dermatological Treatment (2016)

Kristian Reich Craig L. Leonardi Mark Lebwohl Francisco A. Kerdel Yukari Okubo

Background: Scalp is a frequently affected and difficult-to-treat area in psoriasis patients.Objective: We assessed the efficacy of ixekizumab in the treatment of patients with scalp psoriasis over 60 weeks using the Psoriasis Scalp Severity Index (PSSI).Methods: In three Phase 3, multicenter, double-blind, placebo-controlled trials, patients with moderate-to-severe psoriasis in UNCOVER-1 (N = 1296), UNCOVER-2 (N = 1224) and UNCOVER-3 (N = 1346) were randomized to subcutaneous 80 mg ixekizumab every two weeks (Q2W) or every four weeks (Q4W) after a 160 mg starting dose, or placebo through Week 12. Additional UNCOVER-2 and UNCOVER-3 cohorts were randomized to 50 mg bi-weekly etanercept through Week 12. Patients entering the open-label long-term extension (LTE) (UNCOVER-3) received ixekizumab Q4W; UNCOVER-1 and UNCOVER-2 included a blinded maintenance period in which static physician global assessment (sPGA) 0/1 responders were re-randomized to placebo, ixekizumab Q4W, or 80 mg ixekizumab every 12 weeks (Q12W) through Week 60.Results: In patients with moderate-to-severe psoriasis with baseline scalp involvement, PSSI 90 and 100 were achieved at Week 12 in higher percentages of patients treated with ixekizumab Q2W (81.7% and 74.6%) or ixekizumab Q4W (75.6% and 68.9%) compared with patients treated with placebo (7.6% and 6.7%; p < .001 each ixekizumab arm versus placebo) or etanercept (55.5% and 48.1%; p < .001 each ixekizumab arm versus etanercept). These outcomes were maintained through Week 60 of the maintenance (UNCOVER-1 and UNCOVER-2) and LTE (UNCOVER-3) period in patients who continued on ixekizumab Q4W.Conclusion: Ixekizumab was efficacious in treating scalp psoriasis in patients with moderate-to-severe psoriasis, with most patients achieving complete or near-complete resolution of scalp psoriasis and maintaining this response over 60 weeks.

Ixekizumab

10.1080/09546634.2016.1249820

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Citations (47)

[Acroosteolysis associated to palmo-plantar psorisasis].

PubMed (2010)

Jozélio Freire de Carvalho Ricardo Romiti Rosa Maria Rodrigues Pereira

Plantar warts

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Atualização do custo-efetividade por resposta de adalimumabe, etanercepte, guselcumabe, infliximabe, ixequizumabe, secuquinumabe e ustequinumabe no tratamento de psoríase em placas moderada a grave sob a perspectiva do Sistema de Saúde Suplementar brasileiro

Jornal Brasileiro de Economia da Saúde (2022)

Alexander von Reininghaus Rafael L. Gomes Bernardo R. Pires Juares Bianco Renato Picoli

Objetivo: Os agentes biológicos representam um grande avanço no tratamento da psoríase em placas moderada a grave. No entanto, variações de eficácia, segurança e custos dos tratamentos podem dificultar a escolha do agente terapêutico. Este estudo teve como objetivo atualizar o custo por resposta dos agentes biológicos disponíveis para psoríase no ROL de Procedimentos e Eventos em Saúde (ROL) da Agência Nacional de Saúde Suplementar (ANS). Métodos: Uma análise de custo por resposta foi utilizada para avaliar a razão de custo pelo desfecho Índice de Gravidade e Área da Psoríase (PASI) 90. Os resultados foram apresentados para o primeiro ano (ano I), que compreende a fase de indução e a fase manutenção até completar 52 semanas e foi realizada uma análise da efetividade do tratamento num cenário de orçamento fixo. Os custos dos tratamentos foram calculados com base nos preços de fábrica (PF18%) da Tabela da Câmara de Regulação do Mercado de Medicamentos de junho de 2021. Resultados: Para o ano I, o guselcumabe apresentou melhor resultado para custo por resposta (R$ 130.467) PASI 90, seguido por ixequizumabe, ustequinumabe, secuquinumabe, adalimumabe, infliximabe e etanercepte. No cenário com orçamento fixo, o guselcumabe demonstrou ser o agente capaz de tratar com sucesso (PASI 90) o maior número de pacientes. Conclusão: Sob a perspectiva do Sistema de Saúde Suplementar do Brasil, o guselcumabe apresentou o melhor custo por resposta PASI 90, sendo, assim, a terapia com melhor custo-efetividade no tratamento da psoríase em placas moderada a grave disponível no ROL.

10.21115/jbes.v14.n1.p56-62

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Faculty Opinions recommendation of Cigarette smoking and acne in adolescents: results from a cross-sectional study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2007)

Ricardo Romiti

Cross-sectional study

10.3410/f.1069720.522636

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Molluscum contagiosum on tattoo Molusco contagioso em tatuagem

Luciana Molina Ricardo Romiti

2 Abstract: Molluscum contagiosum is a disease caused by a poxvirus characterized by benign self-limited eruption of single or multiple cutaneous spherical and pearly papules. Transmission usually occurs by direct contact with infected hosts. It is reported the case of a 22-year-old Caucasian male who presented characteristic pearly and umbilicated papules strictly located on the region of a tattoo. Histopathologic exam confirmed the diagnosis of molluscum contagiosum. The authors describe an uncommomn manifes- tation of dissemination of this virus in tattoos and also present a literature review emphasizing the trans- mission pathways and treatment of Molluscum contagiosum. Keywords: Molluscum Contagiosum; Poxviridae Infections; Tattoo Resumo: Molusco contagioso e uma dermatovirose causada por poxvirus e caracterizada por erupcao benigna e autolimitada de uma ou multiplas papulas esfericas e brilhantes. A transmissao habitualmente ocorre por contato direto com individuos infectados. Relata-se caso de doente masculino, 22 anos, com historia de surgimento de numerosas papulas umbilicadas localizadas estritamente sobre a regiao de uma tatuagem. Exame histopatologico de uma das papulas confirmou a hipotese clinica de molusco contagioso. Os autores descrevem uma manifestacao pouco frequente da disseminacao desse virus em tatuagens e apre- sentam uma revisao da literatura, enfatizando as vias de transmissao e a terapeutica do molusco contagioso. Palavras-chave: Infeccoes por Poxviridae; Molusco contagioso; Tatuagem

Molluscum contagiosum

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Psoríase pustulosa generalizada (von Zumbusch)

Ricardo Romiti André Luís da Silva Hirayama Marcelo Arnone Renata Ferreira Magalhães

10.1016/j.abdp.2021.11.020

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Eruptive vellus hair cysts in a patient with ectodermal dysplasia

Journal of the American Academy of Dermatology (1997)

Ricardo Romiti Cyro Festa Neto

Vellus hair

10.1016/s0190-9622(97)70294-9

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Citations (23)

Semantic and psychometric validation of the Brazilian Portuguese version (PASE-P) of the Psoriatic Arthritis Screening and Evaluation questionnaire

PLoS ONE (2018)

Carolina Zorzanelli Costa Cláudia Goldenstein‐Schainberg Sueli Carneiro José Joaquim Rodrigues Ricardo Romiti

PASE (Psoriatic Arthritis Screening and Evaluation) was developed in the English language to screen for inflammatory arthritis among patients with psoriasis. It is 15 item self administered questionnaire with a score from 15 to 75. A higher score indicates a greater risk for inflammatory joint disease. The purpose of this study was to translate, adapt and validate this questionnaire into Brazilian Portuguese (PASE-P). 465 patients diagnosed with psoriasis (158 with psoriatic arthritis confirmed by a rheumatologist according to the CASPAR criteria and 307 without) were evaluated in dermatology clinics. We performed the analysis of semantic equivalence in eight steps. For psychometric equivalence, we evaluated the data quality, reliability, construct validity, well-known groups and discriminant characteristics of the items, as well as a ROC curve to determine optimal PASE-P cutoff points in case identification and their sensitivity / specificity. The final version presented excellent reproducibility (CCI = 0.97) and reliability (Cronbach's alpha> 0.9). A cut-off point of 25 distinguished between patients with and without psoriatic arthritis, with sensitivity of 69.5 and specificity of 86.8. PASE-P proved to be culturally valid and reliable to screen for psoriatic arthritis in Brazilian patients with psoriasis.

Brazilian Portuguese

Discriminant validity

10.1371/journal.pone.0205486

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Citations (8)