An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Abstract Background The association of Helicobacter pylori (H. pylori) infection and thyroid disease is still controversial. Chinese adults have an extremely high prevalence of H. pylori infection. The incidence of thyroid diseases has obvious gender difference. The aim of this study was to determine the gender-specific association between H. pylori infection and thyroid disease in Chinese adults. Design: Retrospective analyzed the data of subjects underwent routine physical check-up in the Public Health Center of our hospital between 2019 and 2021. The data included anthropometry and blood biochemical indicators. The serum levels thyroid hormones and thyroid autoantibodies were detected. Thyroid ultrasonography was performed by experienced technicians. The diagnosis of thyroid nodules was according to the thyroid imaging reporting and data system (TI-RADS). Results The women with positive H. pylori had significantly lower FT4 levels, statistically higher uTSH levels, higher prevalence of hypothyroidism, and higher prevalence of positive TPOAb than the women with negative H. pylori. Men with positive H. pylori had significantly higher SBP, statistically lower TT4 and FT4 than the men with negative H. pylori. The prevalence of thyroid heterogeneous echogenicity and TNs in H. pylori positive and negative subjects had no significant difference in both genders. Conclusions The results indicated the prevalence of hypothyroidism and TPOAb positivity was more frequent in females with Helicobacter pylori infection. H. pylori infection may be associated with AITDs in females, but not males. There was no significant association between H. pylori infection and the risk of TNs types in both gender.
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
With the decrease of mobile electronic product volume and weight, fingerprint packaging products used for unlocking need thinner structure. Warpage may occur in ultrathin plastic seal products which seriously affects the producibility of the product. Because of the difference of thermal expansion coefficient of each material in fingerprint packaging products, warping deformation is easy to occur after curing. This paper studies the key factors (material characteristics, product structure, etc.) which affect the warpage of fingerprint products. For a fingerprint packaging product, ANSYS is used Simulation analysis software, the material parameters and product structure are simulated and optimized, and the experimental results show that the combination of simulation and experiment can effectively control and optimize the warpage of the package, which is of great significance to ensure the production of fingerprint products.
Abstract We simulate climate variations in the past 250 million years (Myr), using the fully coupled Community Earth System Model version 1.2.2 (CESM1.2.2) with the Community Atmosphere Model version 4 (CAM4). Three groups of simulations are performed, each including 26 simulations, with a 10‐million‐year interval. The Control group is constrained by paleogeography, increasing solar radiation, and reconstructed global mean surface temperatures (GMSTs) by tuning CO 2 concentrations. No ice sheets are prescribed for all simulations except for the pre‐industrial (PI) simulation in which modern geography, ice sheets and vegetation are used. Simulated zonal mean surface temperatures are always higher than those of proxy reconstructions in the tropics, but lower than those of proxy reconstructions at middle latitudes. The relative importance of individual contributing factors for surface temperature variations in the past 250 Myr is diagnosed, using the energy‐balance analysis. Results show that greenhouse gases are the major driver in regulating GMST variations, with a maximum contribution of 12.2°C. Varying surface albedo contributes to GMST variations by 3.3°C. Increasing solar radiation leads to GMST increases by 1.5°C. Cloud radiative effects have relatively weak impacts on GMST variations, less than ±0.8°C. For comparison, two groups of sensitivity simulations are performed. One group has the CO 2 concentration fixed at 10 times the PI value, and the other group has fixed CO 2 concentration of 10 times the PI value and fixed solar radiation at the present‐day value, showing that varying both paleogeography and solar constant and varying paleogeography alone result in GMST changes by 7.3°C and 5.6°C, respectively.
A new chromium(III) complex, [CrCl(naph-gly)phen]⋅H2O (naph-gly = Schiff base derived from 2-hydroxy-1-naphthaldehyde and glycine, phen = 1,10-phenanthroline), has been synthesized and characterized by elemental analysis, electrospray ionization mass spectroscopy, FT-IR, and X-ray single-crystal diffraction. The chromium(III) complex belongs to the trigonal crystal system, P3(1) space group with crystallographic data: a = b = 1.97017(16) nm, c = 1.02991(7) nm, α = β = 90°, γ =120°, V = 3.4621(5) nm3, Dc = 1.476 g⋅cm−3, Z = 6, F(0 0 0) = 1578, R1 = 0.0508, wR2 = 0.0907. There are two independent molecules in the crystallographic asymmetric unit of the chromium(III) complex. Each CrIII is six-coordinate to form an octahedral geometry. In the crystal, a 3-D structure is formed through intermolecular hydrogen bonds. The calf thymus DNA (CT-DNA)- and bovine serum albumin (BSA)-binding properties of the complex have been studied by UV absorption, fluorescence, and circular dichroism (CD) spectroscopy. Results indicate that the chromium(III) complex binds to CT-DNA in an intercalative mode, and it can bind to BSA and cause conformational changes of BSA.
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