Richard Bonwick

Melbourne Clinic

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The Role of Antidepressants in the Elderly

The Australian Journal of Hospital Pharmacy (1998)

Richard Bonwick

There has been a revolution in antidepressant medication over the last ten years, beginning with the introduction to Australia offluoxetine in 1987. Subsequently a further seven new agents (citalopram, fluvoxamine, moclobemide, nefazodone, paroxetine, sertraline, and venlafaxine) have become available. All these newer agents have fewer side effects than earlier agents. The greatest impact of this revolution has been in the treatment of the elderly, who are particularly sensitive to medication side effects. This review examines all antidepressant agents currently available in Australia, and their role in treating depression and other disorders in the elderly.

Nefazodone

Sertraline

Moclobemide

Paroxetine

Citalopram

Fluvoxamine

Depression

10.1002/jppr1998283187

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Citations (2)

An open label trial of venlafaxine in war veterans with chronic post traumatic stress disorder

Australian & New Zealand Journal of Psychiatry (2000)

Malcolm Hopwood Preethi Morris Paul Debenham Richard Bonwick Ian Parkin

Background: Chronic Post Traumatic Stress Disorder (PTSD) represents a significant and frequent cause of long term disability amongst war veterans. Available estimates suggest that up to 15% of Vietnam War veterans still suffer from PTSD, now some 25 years since the end of the war. This condition has proved relatively refractory, with most forms of treatment showing modest benefits only, once subject to rigorous examination. The pharmacotherapy of Chronic PTSD. Trials of a range of agents including antidepressant medications such as the tricyclics and serotonin specific uptake inhibitors have shown modest and variable benefits beyond treating comorbid depression. It is possible that newer antidepressant medications may prove to have a clearer role in the treatment of PTSD. In the case of Venlafaxine, the combined serotonergic and noradrenergic properties of the compound may result in greater efficacy in chronic PTSD, with particularly action in a broader range of the symptomatology seen in this disorder.O...

Open label

Traumatic stress

Venlafaxine Hydrochloride

10.1080/000486700642

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Citations (4)

Neuroleptic Malignant Syndrome and Risperidone: A Case Report

Australian & New Zealand Journal of Psychiatry (1996)

Richard Bonwick Malcolm Hopwood Philip L.R Morris

Objective: To describe a case of neuroleptic malignant syndrome associated with risperidone. Clinical picture: An elderly patient with bipolar affective disorder presented with neuroleptic malignant syndrome and relapse of hypomania after commencing risperidone. Treatment: Risperidone was ceased and the patient monitored closely. Outcome: The symptoms of neuroleptic malignant syndrome were resolved. Conclusion: To our knowledge this is the first such case reported, and suggests that risperidone, like other neuroleptics, is associated with neuroleptic malignant syndrome.

Neuroleptic Malignant Syndrome

Hypomania

10.3109/00048679609065009

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Citations (15)

Psychotic symptoms and stress

Taylor & Francis eBooks (2010)

Richard Bonwick

10.4324/9780203336984_chapter_15

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Citations (0)

POST-TRAUMATIC STRESS DISORDER IN ELDERLY WAR VETERANS

International Journal of Geriatric Psychiatry (1996)

Richard Bonwick Philip L.P. Morris

Despite it being 50 years since the end of hostilities, a significant number of Second World War (WW2) veterans suffer post-traumatic stress disorder (PTSD) and its associated comorbidities. The prevalence, presentation, course and treatment of this disorder is examined. This examination reveals that PTSD is underdiagnosed in WW2 veterans. Although limited information is available concerning treatment, a broad biopsychosocial approach may be beneficial. The stressors of late life, leading to exacerbation of PTSD, are of particular relevance in this group.

Biopsychosocial model

Stressor

Traumatic stress

Veterans Affairs

10.1002/(sici)1099-1166(199612)11:12<1071::aid-gps511>3.0.co;2-b

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Citations (20)

Electroconvulsive therapy for treatment of late-onset obsessive compulsive disorder

International Psychogeriatrics (2010)

Samantha Loi Richard Bonwick

ABSTRACT An 81-year-old female with no previous psychiatric history presented with late-onset obsessive compulsive disorder following an acute right macular hemorrhage and loss of vision. Following a thorough organic screen to exclude a physical cause, various high doses of selective serotonin reuptake inhibitors were tried with no therapeutic benefit. The patient had significant remission of her symptoms following a course of electroconvulsive therapy.

Serotonin reuptake inhibitor

10.1017/s1041610210000451

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Citations (10)

The history of Yarra Bend Lunatic Asylum, Melbourne

Richard Bonwick

Lunatic

Source

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Citations (2)

Repetitive transcranial magnetic stimulation for major depression: A naturalistic observational study in an Australian private hospital

Psychiatry Research (2020)