T. TANAKA

Nagasaki University Hospital

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Document Type

Co-Authors

Ken Ikeda

Sapporo Kosei General Hospital

Hirotsugu Komatsu

St. Marianna University School of Medicine

Takao Matsuzaki

Mitsubishi Chemical (Japan)

Osamu Yonemitsu

Hokkaido University

Masato Hosoda

Hirosaki University

Y. OIKAWA

Cardiovascular Institute Hospital

Atsunori Hiratsuka

Ibaraki University

Takahide Kishimoto

Toyobo (Japan)

K. HORITA

Hamamatsu Photonics (Japan)

Tetsuro Kikuchi

Niigata University Medical and Dental Hospital

Cooperative Institutions

Hokkaido University

Osaka University

The University of Tokyo

Otsuka (Japan)

Osaka University of Pharmaceutical Sciences

National Institute of Advanced Industrial Science and Technology

Hirosaki University

Keio University

Kyoto University

Kyushu University

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ChemInform Abstract: Novel Cerebroprotective Agents with Central Nervous System Stimulating Activity. Part 1. Synthesis and Pharmacology of 1‐Amino‐7‐hydroxyindan Derivatives.

ChemInform (1991)

Y. Oshiro Y. SAKURAI T. TANAKA Hajime Ueda Tetsuro Kikuchi

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

10.1002/chin.199152160

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Citations (0)

ChemInform Abstract: Synthesis of Anellated γ‐Lactams via Intramolecular 1,3‐Dipolar Cycloadditions of Functionalized N‐Allyl α‐Diazo Amides.

ChemInform (1993)

T. MINAMI Masashi Kamitamari Tomohisa Utsunomiya T. TANAKA Junji Ichikawa

10.1002/chin.199338082

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Diameter dependence of single-walled carbon nanotube with flavin adenine dinucleotide glucose dehydrogenase for direct electron transfer biosensor

The Japan Society of Applied Physics (2019)

Atsuya Suzuki Hitoshi Muguruma Hisanori Iwasa T. TANAKA Atsunori Hiratsuka

Flavin adenine dinucleotide

Glucose oxidase

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Citations (0)

[Platelet cyclic nucleotides and calcium].

PubMed (1979)

T. Yamaki T. TANAKA Hisashi Hidaka

Source

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Citations (1)

Hypoxia alters the energy metabolism and aggregation of washed human platelets.

PubMed (1995)

Michiya Akahori Yasunari Uedono K. Yamagami Naoshi Takeyama Y Kitazawa

Washed human platelets were incubated under hypoxic and normoxic conditions to investigate the influence of oxygen deprivation on energy metabolism and aggregation. The maximum aggregation rate, oxygen consumption, lactate production, and adenine nucleotide content were measured. Hypoxic incubation decreased the oxygen burst and maximum aggregation induced by thrombin, and accelerated anaerobic glycolysis. ATP and ADP levels were preserved, but the hypoxanthine level increased in the incubation medium and the platelet AMP level and adenylate energy charge decreased compared with normoxic incubation. Thus, anaerobic glycolysis failed to compensate for impaired oxidative phosphorylation during hypoxic incubation, suggesting that oxidative energy is essential for full platelet function.

Energy charge

Anaerobic glycolysis

Adenine nucleotide

Hypoxanthine

Hypoxia

Antimycin A

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Citations (19)

ChemInform Abstract: Novel Antipsychotic Agents with Dopamine Autoreceptor Agonist Properties: Synthesis and Pharmacology of 7‐[4‐(4‐Phenyl‐1‐piperazinyl)butoxy]‐3,4‐dihydro‐2(1H)‐quinolinone Derivatives.

ChemInform (1998)

Y. Oshiro Seiji Sato Nobuyuki Kurahashi T. TANAKA Tetsuro Kikuchi

Autoreceptor

10.1002/chin.199827201

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Citations (1)

ChemInform Abstract: Novel Cerebroprotective Agents with Central Nervous System Stimulating Activity. Part 2. Synthesis and Pharmacology of the 1‐(Acylamino)‐7‐ hydroxyindan Derivatives.

ChemInform (1991)

Y. Oshiro Y. SAKURAI T. TANAKA Tetsuro Kikuchi Tetsuro Hirose

10.1002/chin.199152225

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Citations (3)

Diameter Sorting of Thick Semiconducting Carbon Nanotubes by Multi-Step Elution Chromatography

The Japan Society of Applied Physics (2018)

Satoshi Asano T. TANAKA Takeshi Saito Kataura Hiromichi

Carbon fibers

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ChemInform Abstract: Chiral Synthesis of Polyketide‐Derived Natural Products. Part 10. Stereoselective Synthesis of Pikronolide, the Aglycon of the 14‐Membered Ring Macrolide Pikromycin, from D‐Glucose. Role of MPM and DMPM Protection.

Chemischer Informationsdienst (1986)

N. NAKAJIMA Toshihisa Hamada T. TANAKA Y. OIKAWA Osamu Yonemitsu

Abstract The synthesis of picronolide (IXb) Starts with the addition of crotyltributylstannane to the aldehyde obtained by Swern oxidation of the alcohol (I) to give (II) in an erythro‐selective reaction.

Swern oxidation

Diastereomer

10.1002/chin.198648346

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Citations (1)

Glutamic Acid Independent Production of Poly(γ-glutamic acid) byBacillus subtilisTAM-4

Bioscience Biotechnology and Biochemistry (1996)

Yoshihito Ito T. TANAKA Tetsuo Ohmachi Yoshihiro Asada

A bacterium that produced a large amount of poly(γ-glutamic acid) (PGA) when it was grown aerobically in a culture medium containing ammonium salt and sugar as sources of nitrogen and carbon, respectively, was isolated from soil. The bacterium, strain TAM-4, was classified as Bacillus subtilis. The maximum PGA production (22.1 mg/ml) was obtained when it was grown in a medium containing 1.8% ammonium chloride and 7.5% fructose at 30°C for 96 h with shaking. Some properties of the PGA obtained at different times of cultivation were investigated by gel permeation chromatography, SDS–PAGE, and measurement of viscosity, and calculation of the d/l ratio of glutamic acid constituting PGA. The results suggested that PGA was elongated with no changes in the diastereoisomer ratio in the molecule.

Ammonium chloride

Glutamic acid

Strain (injury)

Gel permeation chromatography

10.1271/bbb.60.1239

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Citations (91)