E Bobbio-Pallavicini

Azienda Ospedaliera Ospedale Maggiore

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Camillo Porta

University of Bari Aldo Moro

F Tacconi

Royal Devon & Exeter NHS Foundation Trust

Mauro Moroni

Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo

Riccardo Centurioni

L'organizzazione Ospedale di Civitanova M

A Notario

Georgetown University

Giuseppe Nastasi

University of Pisa

Carlomaurizio Montecucco

University of Pavia

E Ascari

Institute for Chemical and Physical Processes

Nicola Vianelli

Policlinico S.Orsola-Malpighi

Atto Billio

Ospedale di Bolzano

Cooperative Institutions

University of Pavia

Istituti di Ricovero e Cura a Carattere Scientifico

Policlinico San Matteo Fondazione

University of Milan

Ospedale Maggiore

Azienda Ospedaliera Ospedale Maggiore

Fondazione Salvatore Maugeri

Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Azienda di Servizi alla Persona di Pavia (Italy)

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Nitrite and Nitrate Plasma Levels, as Markers for Nitric Oxide Synthesis, in Thrombotic Thrombocytopenic Purpura (TTP)

Hematology (1996)

Camillo Porta I. Buggia Ilaria Bonomi Luigi Gugliotta Nicola Vianelli

The enhanced platelet aggregation and thrombosis occurring in TTP is probably due to an unbalance between agents insulting endothelial integrity and natural antithrombotic factors, such as NO.Using a sensitive and specific HPLC assay, we tested the hypothesis of NO involvement in TTP, comparing NO production, as the stable end-products nitrites and nitrates, in the plasma of 29 TTP patients and of 29 healthy subjects matched for sex and age.Average nitrate titer was 25.868 μM/L in the TTP group vs 24.234 μM/L in the control group (p = n.s.), while nitrite were undetectable in both groups. Moreover, nitrate titers did not correlate with hemoglobin value, platelet count, LDH values, or with Rose and Eldor's severity score.In conclusion, even though the enhanced platelet aggregation observed in TTP could be due to reduced natural antithrombotic substances, NO involvement in the pathogenesis of TTP appears unlikely.

Pathogenesis

Dietary Nitrate

10.1080/10245332.1996.11746310

Cite

Citations (6)

High‐dose human immunoglobulins in thrombotic thrombocytopenic purpura

American Journal of Hematology (1994)

Camillo Porta E Bobbio-Pallavicini

10.1002/ajh.2830450123

Cite

Citations (2)

Cancer Chemotherapy-Related Thrombotic Thrombocytopenic Purpura: Biological Evidence of Increased Nitric Oxide Production

Mayo Clinic Proceedings (1999)

Camillo Porta Marco Danova Alberto Riccardi E Bobbio-Pallavicini Edoardo Ascari

10.4065/74.6.570

Cite

Citations (23)

[Ultrastructural changes in bone marrow lympho-monocytic and myeloblastic elements in whole-body irradiated rats under different conditions].

PubMed (1969)

A Notario E Bobbio-Pallavicini P Scaglione Sebastián Marciano R Rodolico

Whole body irradiation

Source

Cite

Citations (1)

[Ultrastructural changes of the liver tissue in rats kept on a steatogenous, hyperlipid, hypoprotein diet with or without choline].

PubMed (1972)

A Notario E Bobbio-Pallavicini Sebastián Marciano Francesca Bobbio‐Pallavicini

Choline

Liver tissue

Source

Cite

Citations (0)

Low doses of alpha 2B interferon in the treatment of hairy cell leukemia: results of treatment and mean follow-up at 18 months in 13 patients.

PubMed (1994)

G Santagati Giuseppe Nastasi Camillo Porta M Moroni C Santagati

We treated 13 Hairy Cell Leukemia patients with rIFN a 2b. In case of complete/partial response, the patients were submitted to maintenance treatment, while, in case of minimal/no response, a second induction cycle was administered, followed by a maintenance one. The patients were followed, on an outpatients basis, for 18 months at least, obtaining a 100% overall response rate; one patient had complete response, 7 had partial response, and 5 only minimal response. Six patients (46%) relapsed an average of 13 months after the end of the treatment. The utility of a maintenance therapy is discussed.

Complete response

Maintenance therapy

Alpha (finance)

Hairy Cell

Source

Cite

Citations (0)

Lack of Evidence of Antineutrophil Cytoplasmic Antibodies Involvement in the Acute Phase of Thrombotic Thrombocytopenic Purpura

Nephron (1996)

Camillo Porta Roberto Caporali Carlomaurizio Montecucco E Bobbio-Pallavicini

Purpura (gastropod)

Thrombocytopenic purpura

10.1159/000189082

Cite

Citations (2)

Acute rhabdomyolysis during treatment with epsilon aminocaproic acid. Description of two cases.

PubMed (1983)

P Luliri E Bobbio-Pallavicini Marco Gorini

Epsilon-Aminocaproic Acid

Source

Cite

Citations (4)

OCULAR INVOLVEMENT IN ACUTE THROMBOTIC THROMBOCYTO

E Bobbio-Pallavicini Camillo Porta Alessandra Brocchieri A Saporiti F Tacconi

Source

Cite

Citations (0)

Study of release of eosinophil cationic proteins (ECP and EPX) in the hypereosinophilic syndrome (HES) and other hypereosinophilic conditions.

PubMed (1998)

E Bobbio-Pallavicini Marco Confalonieri F Tacconi E. Mainardi Roberto Porta

Up to date, the etiology and the pathogenesis of HES are still unknown and particularly it is unclear why eosinophils in HES are more aggressive towards tissues than in other eosinophilic conditions.We assessed the cationic proteins ECP and EPX serum concentrations, their in vitro release from polymorphonuclear cell culture, and the monoclonal antibodies EG1 and EG2 in 3 patients with HES, 6 patients with other hypereosinophilic conditions and 20 healthy control subjects.Serum ECP and EPX concentrations were higher in eosinophilic patients than in healthy subjects. Hypereosinophilic patients had more EG2+ cells than healthy subjects, but EG2+ rate failed to differentiate HES from other hypereosinophilic conditions (p = 0.074). Moreover, the release in vitro of ECP and EPX was significantly higher in HES patients (p < 0.05).Our preliminary results seem to suggest the importance of functional data, such as ECP and EPX release, in differentiating HES from other hypereosinophilic diseases. Particularly, ECP and EPX release in vitro is higher in cell cultures from HES patients than from patients with other hypereosinophilic conditions.

Hypereosinophilic Syndrome

Pathogenesis

Source

Cite

Citations (6)