Thomas R. Porter

University of Nebraska Medical Center

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Feng Xie

University of Nebraska Medical Center

John Lof

University of Nebraska Medical Center

Feng Xie

McMaster University

Jeane Mike Tsutsui

Universidade de São Paulo

Feng Xie

Second Affiliated Hospital of Nanchang University

Wilson Mathias

Universidade de São Paulo

Edward O’Leary

University of Nebraska Medical Center

E. Carr Everbach

Swarthmore College

Juefei Wu

Southern Medical University

Shelby Kutty

Johns Hopkins Hospital

Cooperative Institutions

University of Nebraska Medical Center

279

Harvard University

116

Universidade de São Paulo

University of Nebraska at Omaha

Brigham and Women's Hospital

Nebraska Medical Center

Mayo Clinic

Columbia University

Mayo Clinic in Arizona

Massachusetts General Hospital

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Myocardial contrast quantitation during stress echocardiography

European Journal of Echocardiography (2006)

A. Elhendy Thomas R. Porter

Please see page 217 for the article by Toledo et al. ( doi:10.1016/j.euje.2005.07.012 ) to which this editorial pertains. Quantification of functional and perfusion abnormalities with stress imaging techniques is an important challenge in the assessment of patients with known or suspected coronary artery disease (CAD). The standard technique for evaluation of CAD with echocardiography relies upon subjective observation of wall motion abnormalities during exercise or pharmacologic stress, with a semi-quantitative approach to evaluate the extent of functional abnormalities using a 16-segment or 3 coronary arterial territorial distribution model.1,2 This approach has permitted the diagnosis of CAD with moderate sensitivity and moderate-to-high specificity. However, the extent of CAD has been consistently underestimated with this method and the sensitivity remains modest particularly in patients with single vessel CAD.3 Furthermore, hard cardiac events are still observed in around 1% annually among patients with a normal wall motion study.4–7 Real time myocardial contrast echocardiography (RTMCI) has been shown to be a safe and feasible …

Stress Echocardiography

10.1016/j.euje.2006.01.003

Cite

Citations (0)

Detection of Subendocardial Ischemia in the Left Anterior Descending Coronary Artery Territory With Real-Time Myocardial Contrast Echocardiography During Dobutamine Stress Echocardiography

JACC. Cardiovascular imaging (2008)

Feng Xie Saritha Dodla Edward O’Leary Thomas R. Porter

Dobutamine

Endocardium

10.1016/j.jcmg.2008.02.004

Cite

Citations (31)

Endocardial Border Delineation during Dobutamine Infusion Using Contrast Echocardiography

Echocardiography (2002)

Wilson Mathias Ana Lúcia Arruda José Lázaro Andrade Orlando Campos Filho Thomas R. Porter

Background: A significant percentage of pharmacologic stress echocardiograms produce suboptimal images despite the use of second harmonic imaging. Intravenous continuous infusion of myocardial ultrasound contrast may enhance endocardial border delineation during dobutamine‐atropine stress echocardiography (DASE), improving wall‐motion analysis. Patients and Methods: We prospectively studied 68 patients (41 males and 27 females), mean age 58 years, with DASE during intravenous infusion of contrast using second harmonic imaging. Dobutamine was infused in scalar doses of 5 μ g/kg/min to 40 μ g/kg/min, and atropine was administered in doses of up to 1 mg. We diluted 0.1 mL of perfluorocarbon‐exposed sonicated dextrose albumin (PESDA) microbubbles into 80 mL of saline solution, which was used for continuous intravenous infusion. Blinded reviewers used a 16‐segment model at rest and peak DASE to analyze segmental wall delineation in two sets of images for each patient, with and without contrast. An endocardial delineation score of 0–3 (nondelineated to excellent delineation) was given to each segment. An endocardial delineation score index (EDSI), the number of endocardial delineation scores for each set of images divided by 16, was created. Results: The analysis of the mean EDSI for the 2176 segments was 1.46 (± 0.43) at rest and 1.30 (± 0.48) at peak for noncontrast images and 2.22 (± 0.52) and 2.29 (± 0.52) for contrast images. Complete left ventricle opacification was obtained in all patients, with a mean dose of 4 mL/min, although in 15 (22%) patients, signs of apical bubble destruction occurred. There were 1768 (81%) of 2176 segments delineated without contrast enhancement and 2057 (95%) of 2176 with enhancement ( P < 0.05 ). Conclusion: Continuous infusion of myocardial ultrasound contrast improves endocardial border delineation using second harmonic imaging in patients undergoing DASE.

Dobutamine

Second-harmonic imaging microscopy

Mechanical index

Stress Echocardiography

Bolus (digestion)

10.1046/j.1540-8175.2002.00109.x

Cite

Citations (39)

THE IMPACT OF SONOTHROMBOLYSIS ON LEFT VENTRICULAR DIASTOLIC FUNCTION AND LEFT ATRIAL MECHANICS IN PATIENTS WITH ST ELEVATION MYOCARDIAL INFARCTION

Journal of the American College of Cardiology (2020)

Hsu Po Chiang Miguel Aguiar Bruno G. Tavares Wilson Mathias Bruno C. Borges

Ventricular Function

10.1016/s0735-1097(20)32277-4

Cite

Citations (0)

Contributors

Elsevier eBooks (2011)

Theodore P. Abraham Harry Acquatella David Adams Deborah A. Agler Josef Aichinger

10.1016/b978-1-4377-2262-8.00116-x

Cite

Citations (0)

PREDICTIVE VALUE OF LUNG AND MYOCARDIAL PERFUSION IMAGING IN ACUTE COVID-19 INFECTION

Journal of the American College of Cardiology (2022)

Thomas R. Porter Karla Costello Gleb Haynatzki Feng Xie Cason Christensen

2019-20 coronavirus outbreak

10.1016/s0735-1097(22)02216-1

Cite

Citations (0)

Simultaneous assessment of wall motion and myocardial perfusion using a rapid acquisition intermittent harmonic imaging pulsing interval of 5–15 hertz following acute myocardial infarction and during stress echocardiography

Journal of the American College of Cardiology (1998)

Thomas R. Porter S. Li William Hiser Rebecca Oster U. Deligönül

Hertz

10.1016/s0735-1097(98)81178-9

Cite

Citations (3)

Effectiveness of lipid microbubbles and ultrasound in declotting thrombosis

Ultrasound in Medicine & Biology (2005)

Feng Xie Jeane Mike Tsutsui John Lof Evan C. Unger Jason M. Johanning

10.1016/j.ultrasmedbio.2005.03.008

Cite

Citations (118)

Right Ventricular Outflow Versus Apical Pacing in Pacemaker Patients with Congestive Heart Failure and Atrial Fibrillation

Journal of Cardiovascular Electrophysiology (2003)

Bruce S. Stambler Kenneth A. Ellenbogen Xiaozheng Zhang Thomas R. Porter Feng Xie

Introduction: Prior studies suggest that right ventricular apical (RVA) pacing has deleterious effects. Whether the right ventricular outflow tract (RVOT) is a more optimal site for permanent pacing in patients with congestive heart failure (CHF) has not been established. Methods and Results: We conducted a randomized, cross‐over trial to determine whether quality of life (QOL) is better after 3 months of RVOT than RVA pacing in 103 pacemaker recipients with CHF, left ventricular (LV) systolic dysfunction (LV ejection fraction ≤ 40%), and chronic atrial fibrillation (AF). An additional aim was to compare dual‐site (RVOT + RVA, 31‐ms delay) with single‐site RVA and RVOT pacing. QRS duration was shorter during RVOT (167 ± 45 ms) and dual‐site (149 ± 19 ms) than RVA pacing (180 ± 58 ms, P < 0.0001). At 6 months, the RVOT group had higher (P = 0.01) role‐emotional QOL subscale scores than the RVA group. At 9 months, there were no significant differences in QOL scores between RVOT and RVA groups. Comparing RVOT to RVA pacing within the same patient, mental health subscale scores were better (P = 0.03) during RVOT pacing. After 9 months of follow‐up, LVEF was higher (P = 0.04) in those assigned to RVA rather than RVOT pacing between months 6 and 9. After 3 months of dual‐site RV pacing, physical functioning was worse (P = 0.04) than during RVA pacing, mental health was worse (P = 0.02) than during RVOT pacing, and New York Heart Association (NYHA) functional class was slightly better (P = 0.03) than during RVOT pacing. There were no other significant differences between RVA, RVOT and dual‐site RV pacing in QOL scores, NYHA class, distance walked in 6 minutes, LV ejection fraction, or mitral regurgitation. Conclusion: In patients with CHF, LV dysfunction, and chronic AF, RVOT and dual‐site RV pacing shorten QRS duration but after 3 months do not consistently improve QOL or other clinical outcomes compared with RVA pacing. (J Cardiovasc Electrophysiol, Vol. 14, pp. 1180‐1186, November 2003)

Ventricular outflow tract

10.1046/j.1540-8167.2003.03216.x

Cite

Citations (216)

Safety and Efficacy of Commercially Available Ultrasound Contrast Agents for Rest and Stress Echocardiography

Journal of the American College of Cardiology (2008)

Melda S. Dolan Simil S. Gala Saritha Dodla Sahar S. Abdelmoneim Feng Xie

Stress Echocardiography

10.1016/j.jacc.2008.08.066

Cite

Citations (158)