Xue Dong

Liaoning Technical University

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Jin Wang

Southwest University of Science and Technology

HaiFang Yin

Tianjin Medical University

Tongjun Zhang

University of Southampton

Min Lin

Chinese Academy of Agricultural Sciences

Chengde Zhang

Zhongnan University of Economics and Law

Jiahui Han

Peking University Third Hospital

Zhengfu Zhou

Henan Academy of Agricultural Sciences

Ming Chen

Southeast University

Hejie Wei

Henan Agricultural University

Mengxue Liu

Nanchang University

Cooperative Institutions

Chinese Academy of Sciences

Shanghai Jiao Tong University

University of Chinese Academy of Sciences

Chinese Academy of Medical Sciences & Peking Union Medical College

Tianjin Medical University

Harbin Medical University

Chinese Academy of Agricultural Sciences

Sun Yat-sen University

Sichuan University

Nanjing Agricultural University

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Clinical analysis of 46 cases of severe acute pancreatitis

Central Plains Medical Journal (2011)

Tongjun Zhang Xue Dong Mengyu Li Chengde Zhang Ben-gang Gong

Objective To investigate the the timing and indications of surgery for patients with severe acute pancreatitis.Methods The clinical datas of 46 patients with SAP from Jan.1999 to Dec.2009 were retrospectively analyzed.Results In this group,22 cases received non-operative treatment and 24 cases received surgical intervention.The overall mortality and overall curative rate were 17.4％ (8/46),82.6％(38/46),respectively.The curative rates in non-operative and in surgical operative group were 77.3 ％(17/22),87.5 ％(21/24),respectively.Conclusions It' s significant to grasp sugery opportunity and indication during the treatment of severe acute pancreatitis,appropriate choice of the time and procedure of surgical intervention can improve survival and cure rate to the greatest extent,and reduce mortality rate and complications of SAP. Key words: Severe acute pancreatitis; Surgery

Cure rate

10.3760/cma.j.issn.1674-4756.2011.23.011

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Biochemical characterization and redesign of the coenzyme specificity of a novel monofunctional NAD+-dependent homoserine dehydrogenase from the human pathogen Neisseria gonorrhoeae

Protein Expression and Purification (2021)

Wanggang Tang Xue Dong Jiang Meng Ya‐Nan Feng Manman Xie

Neisseria gonorrhoeae

10.1016/j.pep.2021.105909

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Predicting support for fine penalty replacing imprisonment: Crime type, the severity of crime, situational factors and demographic characteristics: A factorial survey approach

International journal of law, crime and justice (2024)

Yuxi Shang Xue Dong J H Zhang

Imprisonment

Situational ethics

Factorial

10.1016/j.ijlcj.2024.100717

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sRNA OsiA Stabilizes Catalase mRNA during Oxidative Stress Response of Deincoccus radiodurans R1

Microorganisms (2019)

Yun Chen Xue Dong Wenjie Sun Jiahui Han Jiang Li

Deinococcus radiodurans adapts to challenging environments by modulating gene expression in response to oxidative stress. Recently, bacterial small noncoding RNAs (sRNAs) have been presumed to participate in the transcriptional or translational regulation of stress-responsive genes. We found 24 sRNAs that may be involved in the oxidative stress response of D. radiodurans by deep RNA sequencing. Moreover, a typical stress-inducible sRNA, IGR_3053, named OsiA, was predicted to bind to the mRNA of katA, katE, and sodC by the bioinformatics method. An osiA knockout of D. radiodurans displayed increased sensitivity to H2O2 and the decreased catalase activity and total antioxidant activity, suggesting that OsiA probably serves as a regulator in the adaptation to oxidative environments. Further microscale thermophoresis results demonstrated that OsiA can directly bind to the mRNA of katA, sodC, and katE. The stability test result of katA mRNA showed that its half-life was 2 min in the osiA mutant compared with 5 min in the wildtype(wt) strain. Our results indicated that OsiA can enhance the stability of katA mRNA and the activity of KatA and consequently the oxidation resistance of D.radiodurans. We are the first one to explore the super-strong oxidative stress resistance of D.radiodurans at the level of post-transcriptional regulation, and found a new pathway that provides a new explanation for the long-term adaptability of D.radiodurans in extreme environments.

10.3390/microorganisms7100422

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Efficient low-temperature wastewater treatment by Pseudomonas zhanjiangensis sp. nov.: a novel cold-tolerant bacterium isolated from mangrove sediment

Frontiers in Microbiology (2024)

Miao Li Xixi Hu Tiancheng Ni Yuan Ni C. Li

A novel heterotrophic, cold-tolerant bacterium, designated

Mangrove ecosystem

10.3389/fmicb.2024.1491174

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Expression and significance of Survivin and PTEN in human ampullary carcinoma

Zhongguo yishi zazhi (2012)

Xue Dong Wen Wang Tongjun Zhang Xinjun Li Jian‐qiang Wang

Objective To study the expressions of survivin and PTEN in ampullary carcinoma and their clinical significance.Methods The expressions of Survivin and PTEN proteins were tested by EnVision immunohistochemistry in 40 cases of ampullary carcinomas and 8 cases of normal ampulla of vater as control.Results The positive rate of Survivin in ampullary carcinomas was significantly higher than normal human controls (82.5％ vs 0％,P ＜ 0.01 ).The differences of the expression of Survivin in ampullaty carcinoma of duodenal invasion,pancreatic invasion,and lymph node metastasis were significant ( P ＜0.05 ).Significant differences were also observed in the expression rate of PTEN hetween the patients with ampullary carcinoma and the normal controls (50％ vs 100％,P ＜ 0.01 ).The differences of the expression of PTEN in ampullary carcinoma of duodenal invasion,pancreatic invasion,and lymph node metastasis were significant ( P ＜ 0.05 ).Significantly negative correlation was found between the expression of Survivin and PTEN by using spearman correlation analysis ( r =-0.57,P ＜ 0.01 ).Conclusions The abnormal expression of Survivin and PTEN gene may promote tumor genesis and progression of ampullary carcinomas and it may be used as the marker for prognosis. Key words: Microtubule-associated proteins/ME; PTEN phosphohydrolase/ME; Ampulla of vater/PA/ME; Common bile duct neoplasms/ME

Survivin

Ampulla of Vater

Ampulla

Clinical Significance

10.3760/cma.j.issn.1008-1372.2012.03.010

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Biological Transformation of Medicine and Food Homology Hawthorn with Monascus Ruber to Enhance Lipid-Lowering Function

Xue Dong Yongchao Cai Hui Liao Zehua Chen Yao Wang

Homology

10.2139/ssrn.4657400

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