K.V. Radha

Alagappa University

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S. Sabarunisha Begum

Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology

Subramaniyam Suresh

Amrita Vishwa Vidyapeetham

V. Thamilselvi

Anna University, Chennai

Padmaja

Professor Jayashankar Telangana State Agricultural University

Deepanshu Patel

Dr. Hari Singh Gour University

P. Thyriyalakshmi

Anna University, Chennai

T. Devasena

Anna University, Chennai

S. Swapna Priya

Alagappa University

Joydip Joardar

International Advanced Research Centre for Powder Metallurgy and New Materials

P.S. Chandra Sekhar

Indian Institute of Technology Delhi

Cooperative Institutions

Anna University, Chennai

International Advanced Research Centre for Powder Metallurgy and New Materials

Alagappa University

University of Hyderabad

Indian Institute of Technology Madras

Kerala Veterinary and Animal Sciences University

SRM Institute of Science and Technology

Sri Padmavati Mahila Visvavidyalayam

Universidad de Cádiz

Annamalai University

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Phase formation during mechanically activated annealing of nanocrystalline Cr–60at.%Al

Journal of Alloys and Compounds (2010)

M. Archana Neha Hebalkar K.V. Radha Joydip Joardar

Nanocrystalline material

10.1016/j.jallcom.2010.04.046

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Citations (17)

Preparation and characterization of native poly(3-hydroxybutyrate) microspheres from Bacillus subtilis MTCC 9763

Journal of Bioactive and Compatible Polymers (2014)

S. Saranya K.V. Radha

Poly(3-hydroxybutyrate) is a biodegradable and biocompatible polymer with many potential biomedical applications including medical implants and drug delivery systems. In this study, poly(3-hydroxybutyrate) production by Bacillus subtilis MTCC 9763 was optimized for different physical and chemical parameters. A 90% poly(3-hydroxybutyrate) accumulation was achieved with 2% fructose and 0.5% ammonium sulfate as carbon and nitrogen sources. The effective accumulation occurred at pH 7. The poly(3-hydroxybutyrate) content of dry cell weight increased to 87% at 36 h of incubation. The synthesized poly(3-hydroxybutyrate) was characterized by Fourier transform infrared and nuclear magnetic resonance spectroscopies. The oil-in-water solvent evaporation technique was used to fabricate the poly(3-hydroxybutyrate) microspheres. The surface morphology appeared smooth in the range of 1–2 µm with specific surface area ranging 19 to 20 m 2 /g. The synthesized poly(3-hydroxybutyrate) microspheres were nontoxic and exhibited good cytocompatibility toward NIH 3T3 fibroblasts.

Poly-3-hydroxybutyrate

10.1177/0883911513520380

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Citations (2)

Fabrication of chitosan-bis (4-formyl-2 methoxy phenyl carbonate) Schiff base nanoparticles and evaluation of their antioxidant and anticancer properties

Molecular Biology Reports (2019)

P. Thyriyalakshmi K.V. Radha

Moiety

10.1007/s11033-019-04887-4

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Citations (3)

Electrochemical Oxidation Processes

Elsevier eBooks (2018)

K.V. Radha Karunamoorthy Sirisha

Oxidizing agent

Anodic oxidation

10.1016/b978-0-12-810499-6.00011-5

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Citations (24)

Effect of hydrodynamic characteristics on the performance of biofilm for degrading phenol in inverse fluidized bed biofilm reactor

Desalination and Water Treatment (2014)

S. Sabarunisha Begum K.V. Radha

The influence of some hydrodynamic effects on the performance of biofilm in inverse fluidized bed biofilm reactor (IFBBR) was studied with low-density polystyrene support particles of various sizes (2.9, 3.5, and 3.8 mm) using Pseudomonas fluorescens for the degradation of phenol. The biofilm reactor was operated under different superficial air velocities for a fixed settled bed height of particles to study the effect of hydrodynamics on biofilm thickness, biofilm dry density, bioparticle density, and attached and suspended biomass concentrations for efficient biodegradation of phenol. There is evidence that the chemical oxygen demand reduction and phenol degradation efficiency were found to be high at the optimized superficial air velocity with controlled biofilm thickness and for a stable and dense biofilm dry density. The results of the study revealed that with increase in superficial air velocity, the biofilm thickness and bioparticle density decreases while the biofilm dry density and suspended biomass concentration increases. However, above a critical superficial velocity (optimal superficial velocity) the detachment force does not control the outgrowth of the biofilm anymore and the thickness increases rapidly with decreasing suspended biomass concentration. The optimal superficial velocity for better biodegradation of phenol was found to 0.240, 0.220, and 0.230 m/s for the particle sizes of 2.9, 3.5, and 3.8 mm, respectively. The particle size of 3.5 mm has been found to be the optimal particle size for efficient biodegradation of phenol in IFBBR with better hydrodynamic effects and biofilm morphology.

Superficial velocity

Particle (ecology)

10.1080/19443994.2014.929977

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Citations (9)

Extraction of Bromelain from fruit waste and its effective utilization

Journal of Ecosystem & Ecography (2015)

K.V. Radha

Bromelain

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Deodorization of goat milk by cardamom and pistachio extracts and β-cyclodextrin

Indian Journal of Small Ruminants (The) (2019)

Gopika P.R.K.V. Radha

A study was undertaken to reduce goaty odour in goat milk by cardamom and pistachio extracts and β-cyclodextrin as deodorization agents. Goat milk was incorporated with 0.03% cardamom extract (T1), 0.03% pistachio extract (T2) and 0.25% β-cyclodextrin (T3) for deodorization. Goat milk without any deodorization agent was used as control. Physico-chemical, microbiological and sensory qualities of control and treated goat milk samples were assessed. No significant change in pH, titratable acidity, fat, total solids and microbiological quality was observed between the control and the treatment groups. On sensory evaluation, goat milk incorporated with cardamom and pistachio extracts had higher sensory scores than the control and goat milk incorporated with β-cyclodextrin. Among the three agents studied for deodorization, cardamom and pistachio extracts were found effective in reducing the goaty odour. The treated goat milk samples could be stored up to one week at refrigerated storage without any deterioration in microbiological quality. It was concluded that goat milk can be successfully deodorized by cardamom and pistachio extracts.

10.5958/0973-9718.2019.00030.8

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Citations (1)

EVALUATION OF MERREMIATRIDENTATA MUCILAGE AS BINDING AGENT INTABLET DOSAGE FORMS

RASAYAN Journal of Chemistry (2017)

M. Vidyavathi K.V. Radha A V Rajyalakshmi R Ramya

An increasing interest in the use of natural polymers or gums in pharmaceutical formulations focusing the tremendous orientation to discover and extract such gums.The pharmaceutical industry is ever thirsty to satisfy patient's therapeutic needs by utilizing inactive excipients along with active ingredients in formulation development.Binders are added to tablet formulations to add cohesiveness to powders thereby providing the necessary bonding to form granules which under compaction form a compact mass as tablet.Binders are also essential to achieve the hardness of the tablet.The development of new excipients for potential use as binding agent in tablet formulations continues to be of interest.The present paper consisted of the evaluation of mucilage of Merrimia tridentata roots for its binding property in solid dosage forms by using starch as a standard binder.Ibuprofen was used as a model drug and tablets were prepared using mucilage obtained from roots of Merremia tridentate as a test binder and starch as standard binder by wet granulation method.The granules were evaluated for flow properties, drugexcipient compatibility and compressibility index and tablets were evaluated for weight variation, hardness, friability, disintegration time and dissolution rate.The similarity factor was determined for comparison of dissolution profiles of test and standard tablets.It has been found from the present study that the roots of plant Merremia tridentata has a good mucilage content which may be taken as a good natural source of mucilage for better binding properties with comparable flow properties, disintegration time, hardness and release rate similar to starch.

Mucilage

10.7324/rjc.2017.1021614

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Comparative Evaluation of Antioxidant Activity of Four Indigenous Herbal Plants and their Polyherbal Extract

K.V. Radha Padmaja P Ajithkumar H Bisson William Sri Narayana

In a normal cell, there is appropriate oxidant: antioxidant balance. However, this balance can be shifted, when oxidant species is increased or when levels of antioxidants are diminished. This stage is called oxidative stress. Oxidative stress causes serious cell damage leading to a variety of human diseases like Alzheimer’s disease, Parkinson’s disease, atherosclerosis, cancer, arthritis, immunological incompetence and neurodegenerative disorders, etc. Numerous polyherbal formulations, which are combinations of different herbal extracts/fractions, are used for the treatment of these diseases, as herbal drugs are a rich source of natural antioxidants. The aim of this study was to compare the antioxidant activity of the extracts of four different plants viz Tinospora cordifolia (Menispermaceae), Withania somnifera (Solanaceae), Azadiracta indica (Meliaceae), and Centella asiatica (Apiaceae) with their polyherbal extract and explore the synergic action for designing new drug combinations that are individually sub therapeutic but efficacious in combinations. The crude alcoholic extract of these individual plants and their polyherbal combination were studied for their antioxidant activity by Nitric oxide scavenging assay, Hydroxyl radical scavenging assay, Reducing power capacity, Superoxide free radical scavenging assay and Total antioxidant activity. The crude extracts showed different level of antioxidant activity and is a potential source of antioxidants and thus could prevent many radical related diseases.

Tinospora cordifolia

Centella

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Experimental study on corrosion inhibition of mild steel using Mukia maderaspatana leaves extract as green inhibitor

Surface Science and Technology (2024)

K.V. Radha Deepanshu Patel Varshith Vijayan Nithya Saravanan Dharmaraj

Corrosion inhibitor

10.1007/s44251-024-00056-3

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