Seok-Hyung Kim

Wonkwang University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Cheol‐Hee Kim

Chungnam National University

Tae-Lin Huh

Kyungpook National University

Hae‐Chul Park

Korea University

Sung-Kook Hong

Kyungpook National University

Hyung-Seok Kim

Chonnam National University

Sang-Yeob Yeo

Hanbat National University

Myungchull Rhee

Chungnam National University

Jimann Shin

Washington University in St. Louis

Sangtae Han

Kyungpook National University

Ajay Chitnis

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Cooperative Institutions

Kyungpook National University

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Institutes of Health

Chungnam National University

Hanbat National University

Korea University

Osaka University

Harvard University

Animal and Plant Quarantine Agency

Ansan University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Characterization and expression of a presomitic mesoderm-specific mespo gene in zebrafish

Development Genes and Evolution (2003)

Kyeong-Won Yoo Cheol‐Hee Kim Hae‐Chul Park Seok-Hyung Kim Hyung-Seok Kim

Epiboly

Paraxial mesoderm

Blastoderm

Intermediate mesoderm

Somitogenesis

10.1007/s00427-003-0312-1

Cite

Citations (17)

Eye field requires the function of Sfrp1 as a Wnt antagonist

Neuroscience Letters (2006)

Hyung-Seok Kim Jimann Shin Seok-Hyung Kim Hang-Suk Chun Jun‐Dae Kim

Forebrain

Diencephalon

Hindbrain

10.1016/j.neulet.2006.12.027

Cite

Citations (15)

Characterization of two frizzled8 homologues expressed in the embryonic shield and prechordal plate of zebrafish embryos1The entire nucleotide sequences for Zfz8a and Zfz8b cDNA were deposited to the GenBank database under the Accession numbers AF060697 and AF060696, respectively.1

Mechanisms of Development (1998)

Seok-Hyung Kim Hae‐Chul Park Sang-Yeob Yeo Sung-Kook Hong J.W. Choi

Notochord

Blastoderm

Convergent extension

Epiboly

10.1016/s0925-4773(98)00137-3

Cite

Citations (31)

Structural comparison of zebrafish Elav/Hu and their differential expressions during neurogenesis

Neuroscience Letters (2000)

Hae‐Chul Park Sung-Kook Hong Hyung-Seok Kim Seok-Hyung Kim Eun-Ja Yoon

10.1016/s0304-3940(99)00940-4

Cite

Citations (87)

Specification of an anterior neuroectoderm patterning by Frizzled8a-mediated Wnt8b signalling during late gastrulation in zebrafish

Development (2002)

Seok-Hyung Kim Jimann Shin Hae‐Chul Park Sang-Yeob Yeo Sung-Kook Hong

Wnts have been shown to provide a posteriorizing signal that has to be repressed in the anterior neuroectoderm for normal anteroposterior (AP) patterning. We have previously identified a zebrafish frizzled8a (fz8a) gene expressed in the presumptive anterior neuroectoderm as well as prechordal plate at the late gastrula stage. We have investigated the role of Fz8a-mediated Wnt8b signalling in anterior brain patterning in zebrafish. We show that in zebrafish embryos: (1) Wnt signalling has at least two different stage-specific posteriorizing activities in the anterior neuroectoderm, one before mid-gastrulation and the other at late gastrulation; (2) Fz8a plays an important role in mediating anterior brain patterning; (3) Wnt8b and Fz8a can functionally interact to transmit posteriorizing signals that determine the fate of the posterior diencephalon and midbrain in late gastrula embryos; and (4) Wnt8b can suppress fz8a expression in the anterior neuroectoderm and potentially affect the level and/or range of Wnt signalling. In conclusion, we suggest that a gradient of Fz8a-mediated Wnt8b signalling may play crucial role in patterning the posterior diencephalon and midbrain regions in the late gastrula.

Neuroectoderm

Diencephalon

10.1242/dev.129.19.4443

Cite

Citations (91)

Zebrafish PEX1 Is Required for the Generation of GABAergic Neuron in p3 Domain

Development & Reproduction (2024)

Jae-Ho Ryu Min-Jung Kim Aseung Kim Hyunju Ro Seok-Hyung Kim

Maintenance of neural progenitors requires Notch signaling in vertebrate development. Previous study has shown that Jagged2-mediated Notch signaling maintains proliferating neural progenitors in the ventral spinal cord. However, components for Jagged-mediated signaling remain poorly defined during late neurogenesis. Here we performed yeast-two hybrid screening by using the intracellular domain (ICD) of zebrafish Jagged2, and investigated a possible role of PEX1 as a component of Notch signaling for the cell-fate decision and the differentiation of neural precursors in p3 domain. Western blotting showed that zebrafish PEX1 might interacts with the ICD of zebrafish Jagged2 physically. PEX1 morpholino-injected embryos showed the increased number of GABAergic KA" neurons as well as the ectopic expression of secondary motor neurons in the p3 domain. The increased number of KA" neurons was also observed in the zebrafish embryos with PEX1 mutation induced by CRISPR/Cas9. These phenotypes resemble with that of Jagged2 morphant. Our observations imply that a critical role of PEX1 in the cell-fate decision of proliferating neural precursors in the p3 domain during the continuing growth and development of the vertebrate nervous system.

10.12717/dr.2024.28.4.129

Cite

Citations (0)

Analysis of Upstream Elements in the HuC Promoter Leads to the Establishment of Transgenic Zebrafish with Fluorescent Neurons

Developmental Biology (2000)

Hae‐Chul Park Cheol‐Hee Kim Young‐Ki Bae Sang‐Yeob Yeo Seok-Hyung Kim

TATA box

CAAT box

10.1006/dbio.2000.9898

Cite

Citations (416)