Nodular regenerative hyperplasia was found in nine patients who had hematological disease including polycythemia vera, agnogenic myeloid metaplasia, primary thrombocythemia, rheumatoid arthritis with thrombocytosis, multiple myeloma, and erythrocytosis associated with polycystic renal disease. Portal hypertension was suspected in three and features of hypersplenism were present in four. 2. Nodular regenerative hyperplasia occurred in livers which had widespread obliteration of portal vein radicals (obliterative portal venopathy). Morphometric analysis indicated that the portal vein lesions were predominately located in veins up to 0.2 mm in diameter and were significantly more frequent than similar lesions occurring in elderly persons. 3. The following pathogenesis of nodular regenerative hyperplasia is proposed: Thrombi, perhaps largely composed of platelet aggregates formed in the portal venous circulation or spleen, embolize to the liver and results in obliterative vascular lesions. Atrophy and regenerative nodule formation occur in response to the interruption of the portal blood supply.
summary The purpose of this study was to develop a battery of dental, nutritional and psychological health survey measures and to use this survey instrument to explore links between age, tooth loss and dietary risk. The survey was undertaken in a dental school and hospital. Forty‐nine consecutive patients (age range 25–74 years) participated in this pilot study and completed the health survey instrument. A quarter of the patients reported changing dietary habits due to dental problems, 56% reported difficulty in chewing as a result of problems with their teeth or dentures, and 36% reported having to interrupt meals due to dental difficulties. Tooth number was associated with MNA scores (0·35, P = 0·03, Pearson's correlation coefficient) and reported number of foods eaten (0·33, P = 0·04, Pearson's correlation coefficient) from the questionnaire checklist. Lower MNA scores were associated with age ( F = 6·54; d.f. = 1, 46; P < 0·01) indicating that older adults were more at risk of poor nutritional status. Overall health was not rated as an important factor influencing food choice, and only 14% of the sample felt that they had nutritional problems. Poor diet and impaired food choice was associated with declining numbers of teeth and increasing age. Older adults may require dietary advice to increase awareness of the importance of a healthy diet.
This study explored the experiences of edentulous patients for their perceptions of tooth loss and patient attitudes to treatment options for rehabilitation of the edentate state.Purposive sampling was used to recruit edentate patients with varying denture-wearing experience from two dental hospitals in the Republic of Ireland. Sixteen edentate patients, aged 59 to 83 years, of whom 12 were women and four men were interviewed. Interviews were transcribed, and thematic analysis was undertaken.Findings from this study reflect previous studies, whereby some patients indicated dissatisfaction with the functionality of their dentures. The majority of participants had no regret regarding the loss of their teeth, and despite dissatisfaction with dentures, they would not consider other forms of treatment. Finance was not considered an issue in determining whether to seek out treatment by these participants. These participants expressed a reluctance to get new dentures in case they were more problematic.This study illustrates that some elder edentate patients were dissatisfied with the functionality of their dentures and raised concerns that about the quality of dentures which may be provided to them by dentists. These participants identified clinical dental technicians as a preferred point of contact for their care. Consideration should be given to new oral healthcare delivery models which are accessible and acceptable to future elders.
Changing health behaviours is an important and difficult task. Despite growing interest in behavioural theories and models, there is a paucity of research examining their validity in explaining oral health behaviours, and there is a need for interventional studies to assess their effectiveness in improving oral health. This study aims to test the explanatory power of the dominant psychological theories, develop theory-derived intervention and evaluate its effectiveness in improving oral health of older adults.
Background:
There is long-standing evidence of an association between cutaneous xanthomas and underlying lipid metabolism disorders, impaired glucose tolerance, secondary hyperlipoproteinemia and diabetes mellitus. Since the advent of capsule endoscopy (CE), substantial numbers of endoscopies have shown evidence of small bowel xanthomas. These have unknown significance to the patient and, consequently, are not routinely reported when identified. Our research is the first study to investigate the significance of small bowel xanthomas identified on CE with underlying lipid disorders or diabetes mellitus. Methods:
54 patients participated in this prospective cohort study. We recorded patients’ demographic details, medical history, medication list, height, weight, and waist circumference measurements. A blood sample for fasting lipids, fasting glucose and HbA1c was collected. A blinded gastroenterologist reported whether xanthomas were present and quantified the number of xanthomas. Results:
37% of participants had small bowel xanthomas visualised during CE. The presence of xanthomas was associated with a previous diagnosis of hyperlipidaemia currently treated with anti-lipid medication (IRR 4.43; 95%CI 1.32 to 14.9; p =0.048) and was also associated with increasing units of alcohol consumption (IRR 1.91; 95%CI 1.32 to 2.78; p =0.0007). Conclusion:
This demonstrates an association between the presence of small bowel xanthomas with hyperlipidaemia, mainly in patients with hyperlipidaemia controlled by medication. We also detected an association between small bowel xanthomas and increased alcohol intake. The presence of small bowel xanthomas might trigger lipid evaluation, in future clinical practice.
Abstract – Single tooth implant systems have been shown to offer a safe and highly predictable option for the replacement of anterior teeth. There is however, a paucity of evidence on the result of trauma to single tooth implant systems, particularly in the vulnerable anterior maxillary area. This article presents a report on the outcome of a traumatic incident to an osseointegrated single tooth implant.
MINVILLE, Esdras, Les Affaires — l'homme — les carrières. Fides, Montréal et Paris, 1965. 176 p. Coll. Bibliothèque économique et sociale. 5¾ x 8.. Un article de la revue Revue d'histoire de l'Amérique française (Volume 20, numéro 3, décembre 1966, p. 345-524) diffusée par la plateforme Érudit.
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