Ikechukwu O. Amagwula

Federal University of Technology Owerri

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i-10 index

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Chinaza Godswill Awuchi

Kampala International University

Victory S. Igwe

Federal University of Technology Owerri

Hannington Twinomuhwezi

Kyambogo University

Chijioke M. Osuji

Federal University of Technology Owerri

Sonia Morya

Lovely Professional University

Sarvarian Maryam

Islamic Azad University, Tehran

Chinelo Kate Echeta

Federal University of Technology Owerri

Patrick Maduabuchi Aja

Kampala International University

Chinenyenwa Gloria Omeire

Federal University of Technology Owerri

Allan Isiaga Gonzaga

Cooperative Institutions

Federal University of Technology Owerri

Kampala International University

ACPM Dental College and Hospital

Karpagam Academy of Higher Education

Kyambogo University

Islamic Azad University, Tehran

Ebonyi State University

Mbarara University of Science and Technology

Kampala University

Lovely Professional University

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Fungal Growth and Mycotoxins Production: Types, Toxicities, Control Strategies, and Detoxification

IntechOpen eBooks (2021)

Chinaza Godswill Awuchi Erick Nyakundi Ondari Josiah Eseoghene Ifie Hannington Twinomuhwezi Ikechukwu O. Amagwula

Fungal growth and the production of mycotoxins are influenced by several factors. Environmental conditions such as temperature, water activity, and humidity affect mycotoxin production and fungal growth. Other factors such as pH, fungal strain, and substrate also play roles. Common mycotoxins include aflatoxins, fumonisins, trichothecenes, sterigmatocystin (STC), citrinin, ergot alkaloids, ochratoxins, zearalenones (ZEAs), patulin, deoxynivalenol (DON), Alternaria toxins, tremorgenic mycotoxins, fusarins, cyclochlorotine, sporidesmin, 3-nitropropionic acid, etc. These toxins cause many health conditions in animals and humans, including death. A comprehensive approach starting from the field before planting, continuing throughout the entire food chain is required to control mycotoxin contamination. Good practices, such as proper field practices before and after planting, good harvest practices and postharvest handling, and proper drying and storage measures, help reduce mycotoxin contamination. Several physical, biological, and chemical techniques have been applied to help reduce/eliminate mycotoxin contamination. Food processing also play slight role in mycotoxins removal.

Patulin

Citrinin

Sterigmatocystin

Ochratoxins

10.5772/intechopen.100207

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Citations (15)

Effects of soaking time and freezing on the gel strength of Moi-Moi prepared from Cowpea grains

Biogenesis Jurnal Ilmiah Biologi (2022)

Ikechukwu O. Amagwula Chijioke M. Osuji Chinenyenwa Gloria Omeire Umama Yezdani Mohammad Gayoor Khan

Mechanical strength

10.24252/bio.v10i1.19599

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Citations (2)

Effects of repeated deep frying on refractive index and peroxide value of selected vegetable oils

Chinaza Godswill Awuchi Ikechukwu O. Amagwula Victory S. Igwe Allan Isiaga Gonzaga

Peroxide value

Deep frying

Value (mathematics)

Peroxide

Source

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Citations (29)

Combined impact of freezing and soaking times on different cowpea varieties' flour functionality and resultant gel strength, sensory and product yield of moi-moi

AIMS Agriculture and Food (2022)

Ikechukwu O. Amagwula Chijioke M. Osuji Gloria C. Omeire Chinaza Godswill Awuchi Charles Odilichukwu R. Okpala

<abstract> <p>The preparation of moi-moi either from cowpea flour (processed by dry-milling) or paste (processed by wet-milling) has evolved from the indigenous processing methods. Feasibly, freezing should enhance the characteristics of the cowpea grain, and when combined with conventional processing, help to improve emergent products. In this current work, therefore, the combined impact of freezing with soaking times on different cowpea varieties' flour functionality and resultant gel strength, sensory and product yield of moi-moi were studied. Analysis of flour functionality involved the determinations of moisture content, bulk density, oil absorption capacity, swelling index and water absorption capacity, whereas those of moi-moi products involved gel strength, sensory and (product) yield. Across the cowpea flour samples, the functional attributes significantly differed (p < 0.05). Moi-moi products' gel strength of dry-milled appeared higher than wet-milled by specific variety and soaking times. Moi-moi products' sensory attributes of taste, color, texture and general acceptability resembled (p > 0.05), except for the aroma (p < 0.05). Moi-moi products' yield varied widely (p < 0.05) by different reconstituted water volumes. Overall, combining freezing with conventional processing that involved reconstituted water volumes of cowpea promises an enhanced moi-moi yield.</p> </abstract>

10.3934/agrfood.2022047

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Citations (9)

The Biochemistry, Toxicology, and Uses of the Pharmacologically Active Phytochemicals: Alkaloids, Terpenes, Polyphenols, and Glycosides

Zenodo (CERN European Organization for Nuclear Research) (2020)

Chinaza Godswill Awuchi Ikechukwu O. Amagwula

Terpene

10.5281/zenodo.3967809

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Citations (1)

Environmental Pollutants and Contaminants of Emerging Concern: An African Perspective

Journal La Lifesci (2021)

Chinaza Godswill Awuchi Ikechukwu O. Amagwula

This review focuses on the environmental pollutants and contaminants of emerging concern in Africa. There is increasing reports and identification of ecotoxicological impact of contaminants of emerging concern (CECs), such as plastic, pharmaceutical products, modern pesticides, and personal care products, in terrestrial and aquatic environment within Africa. Identification of CECs, including pharmaceuticals, plastic wastes, pesticide residues, fungal toxins, and personal care products, have been documented in African region including in sediments, sludge, treated drinking water, surface water, wastewater, groundwater, land, solid deposits, etc. Some of the emerging pollutants of concern to environment and humans include lindane, heptachlor, endrin, endosulfan, dieldrin, dichlorodiphenyltrichloroethane (DDT), benzaldehyde, aldrin, bisphenol A, phthalates, bisphenol S, etc. There is need for more studies to identify and quantify the existing and more emerging pollutants.

Aldrin

Endrin

Heptachlor

Lindane

Endosulfan

10.37899/journallalifesci.v2i3.418

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Citations (5)

Protein Functions and Structure Prediction with I-TASSER, a Novel Technology

Journal of Chemical Biological and Physical Sciences (2022)

Chinaza Godswill Awuchi Hannington Twinomuhwezi Victory S. Igwe Sarvarian Maryam Ikechukwu O. Amagwula

Determining a protein structure is a vital approach to understand the function of the protein, which is important in nutrition, nutraceuticals, drug development, food sciences, biosciences, drug delivery, etc.The Iterative Threading ASSembly Refinement (I-TASSER) algorithm is used for automated prediction of protein structure a n d function.I-TASSER uses bioinformatics for the prediction of the model of threedimensional structure of molecules of protein from amino acid sequences.I-TASSER senses templates of the structure from the PDB using a technique known as fold recognition.The full-length models of structure are created by reassembling fragments of structures from threading templates by replica exchange Monte Carlo simulations.It is among the most successfully used methods for predicting protein structure and function in the community-wide experiments of Critical Assessment of protein Structure Prediction (CASP).I-TASSER is used to predict protein structure and function, including ligand-binding site, gene ontology (GO), active sites, enzyme commission (EC) number, etc.

10.24214/jcbps.b.11.4.55567

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Citations (3)

Heat of Combustion of Coffee Pulp and Husks as Alternative Sources of Renewable Energy

European Journal of Agriculture and Food Sciences (2021)

Hannington Twinomuhwezi Pius Wozeyi Victory S. Igwe Ikechukwu O. Amagwula Chinaza Godswill Awuchi

The study determined the amount of heat energy (heat of combustion) produced per unit mass from coffee pulp and coffee husks to see if these can be used as alternative sources of energy. The samples were obtained from Mount Elgon areas in Eastern Uganda. The objectives determined the amount of heat produced per unit mass from coffee husk and pulp and compared the amount of heat produced per unit mass from the coffee husk and coffee pulp. The coffee husk and pulp were dried, ground and sieved using a 150 microns diameter sieve. The resultant powder was analyzed using IKA C200 bomb calorimeter. The Heat values produced per unit mass from coffee husk and pulp were 15.389KJg-1 and 13.755KJg-1 respectively. Further analysis showed that both coffee pulp and coffee husks could be used as fuels for renewable energy. However, from the findings, it is recommended that coffee husks should be preferred as a better source of fuel since it generated 1.634KJg-1 more energy than the coffee pulp. Comprehensive study should be carried out on the two samples to obtain a complete fuel description of the samples.

Husk

Heat of combustion

10.24018/ejfood.2021.3.2.241

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Citations (11)

New Psychoactive Substances: Major Groups, Laboratory Testing Challenges, Public Health Concerns, and Community-Based Solutions

Journal of Chemistry (2023)

Chinaza Godswill Awuchi Patrick Maduabuchi Aja Nancy Bonareri Mitaki Sonia Morya Ikechukwu O. Amagwula

Across communities worldwide, various new psychoactive substances (NPSs) continue to emerge, which worsens the challenges to global mental health, drug rules, and public health risks, as well as combats their usage. Specifically, the vast number of NPSs that are currently available, coupled with the rate at which new ones emerge worldwide, increasingly challenges both forensic and clinical testing strategies. The well-established NPS detection techniques include immunoassays, colorimetric tests, mass spectrometric techniques, chromatographic techniques, and hyphenated types. Nonetheless, mitigating drug abuse and NPS usage is achievable through extensive community-based initiatives, with increased focus on harm reduction. Clinically validated and reliable testing of NPS from human samples, along with community-driven solution, such as harm reduction, will be of great importance, especially in combating their prevalence and the use of other illicit synthetic substances. There is a need for continued literature synthesis to reiterate the importance of NPS, given the continuous emergence of illicit substances in the recent years. All these are discussed in this overview, as we performed another look into NPS, from differentiating the major groups and identifying with laboratory testing challenges to community-based initiatives.

harm reduction

Drugs of abuse

Psychoactive substance

10.1155/2023/5852315

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Citations (9)