Giuseppe Benagiano

Sapienza University of Rome

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Sun‐Wei Guo

Longhua Hospital Shanghai University of Traditional Chinese Medicine

Ivo Brosens

KU Leuven

Manuela Farris

Sapienza University of Rome

Sabina Carrara

Sapienza University of Rome

Valentina Filippi

Sapienza University of Rome

Carlo Bastianelli

Sapienza University of Rome

Marwan Habiba

University Hospitals of Leicester NHS Trust

E. Diczfalusy

Karolinska Institutet

Jan J. Brosens

University of Warwick

F. M. Primiero

Sapienza University of Rome

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National University of Singapore

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Health and Human Development (2HD) Research Network

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Sapienza University of Rome

Harvard University

World Health Organization

University of North Carolina at Chapel Hill

Anna Needs Neuroblastoma Answers

RELX Group (United States)

Memorial Hospital of South Bend

Istituto Superiore di Sanità

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The Italian Constitutional Court modifies Italian legislation on assisted reproduction technology

Reproductive BioMedicine Online (2009)

Giuseppe Benagiano Luca Gianaroli

Constitutional court

Assisted Reproductive Technology

10.1016/j.rbmo.2009.11.025

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Citations (38)

Sex Preselection: an aid to couples or a threat to humanity?

Human Reproduction (1999)

Giuseppe Benagiano

On September 10 1998 the Italian press reported the discovery of a new method to predetermine the sex of a new baby with 90% accuracy. The method is beneficial in many ways and no ethical impediments to the technology have been noted from the point of view of the fetus or of the couple requesting the preselection for strictly medical reasons. However the safety and benefits of the technology is only part of the issue. There is a possibility that sex preselection requested by a couple because of preference for a baby of a specific sex may create injustice discrimination and bias at the level of a community a country or the world as a whole. The problem is that if applied on a large scale couples will use the technology to not have a female baby. Several brief considerations show very clearly that a readily available sex predetermination test will inevitably worsen the already terrible situation existing in various parts of the world in terms of womens rights. It is also bound to create an overall imbalance in the male-to-female ratio worldwide. Hence sex preselection should be submitted to severe limitation.

Injustice

10.1093/humrep/14.4.868

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Citations (41)

The Depo-Provera debate commentary on the article “Depo-Provera, a critical analysis”

Contraception (1981)

Giuseppe Benagiano Ian S. Fraser

10.1016/0010-7824(81)90056-1

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Citations (27)

Introduction

Global Bioethics (1996)

Giuseppe Benagiano

10.1080/11287462.1996.10800943

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The Di Bella multitherapy trial. Criticism ignores standard methodology of cancer treatments.

PubMed (1999)

Roberto Raschetti Donato Greco Francesca Menniti‐Ippolito Stefania Spila Alegiani Giuseppe Benagiano

BELLA

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Neonatal uterine bleeding as antecedent of pelvic endometriosis

Human Reproduction (2013)

I. Brosens Jan J. Brosens Giuseppe Benagiano

We elaborate on a new theory to explain pelvic endometriosis, including endometriosis in premenarcheal girls, based on the finding that the neonatal endometrium can display secretory activity immediately after birth and, in some cases, changes analogous to those seen at menstruation in adults. The neonatal uterus is therefore capable of shedding its endometrium. Indeed, occult vaginal bleeding occurs in a majority of neonates, although overt bleeding is estimated to occur in only 5% of neonates. This may be due to functional plugging of the endocervical canal in the neonate, which in turn would promote retrograde flux of endometrial cells contained in menstrual debris. Ectopic endometrial implantation in a newborn with hydrometrocolpos has been documented. These data, coupled with the observation of a significantly increased risk of endometriosis in adolescents with cervical outflow obstruction and patent Fallopian tubes, indicate that endometriosis, especially in children and young adolescents, may originate from retrograde uterine bleeding soon after birth.

Menstruation

Vaginal bleeding

Cervical canal

10.1093/humrep/det359

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Citations (70)

Having a baby: a ‘gift from God’, or a custom-made purchase?

Gynecological Endocrinology (2000)

Giuseppe Benagiano Alessandra Pera Bruno Dallapiccola

Gift-giving

10.3109/09513590009167684

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Citations (1)

Italian changes are not surprising

Nature Medicine (1999)

Giuseppe Benagiano

10.1038/12383

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The evolution of the meaning of sexuality: procreation or recreation?

Sexologies (2008)

Giuseppe Benagiano

Homo sapiens

Sexual intercourse

Sexual attraction

Sex organ

10.1016/s1158-1360(08)72510-6

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Comment on: Toward an optimal contraception dosing strategy

PLoS Computational Biology (2024)

Giuseppe Benagiano Andrea R. Genazzani Giovanni Grandi Sun‐Wei Guo Marwan Habiba

The optimal contraception dosing strategy proposed by Gavina et al. recently is a commendable attempt to model a complex physiological process with potenial to apply to real-life data. However, there is a need to take into account the real challenges that arise when moving from the theory to its practical application, and it is important that lessons learnt from clinical studies be taken into consideration in any theoretical modelling. In this manuscript, we spell out these lessons and elaborate practical challenges facing their model.

Spell

10.1371/journal.pcbi.1012398

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