Daniel Hernández-Vaquero Panizo

Universidad de Oviedo

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Isaac Pascual

Universidad de Oviedo

Jacobo Silva Guisasola

Central University Hospital of Asturias

Alberto Alperi

Central University Hospital of Asturias

Rocío Díaz Méndez

Central University Hospital of Asturias

César Morı́s

Central University Hospital of Asturias

Juan C. Llosa

Central University Hospital of Asturias

Pablo Avanzas

Central University Hospital of Asturias

J.L. Naya

Universitat Autònoma de Barcelona

María Vigil-Escalera Díaz

Central University Hospital of Asturias

Carlos Morales

Instituto Nacional de Rehabilitación

Cooperative Institutions

Central University Hospital of Asturias

Instituto de Investigación Sanitaria del Principado de Asturias

Universidad de Oviedo

Gobierno del Principado de Asturias

Centro de Investigación en Red en Enfermedades Cardiovasculares

Centro de Investigación Biomédica en Red

Instituto de Salud Carlos III

Montreal Heart Institute

Sociedad Española de Cardiología

Université Laval

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Pulmonary regurgitation after repaired tetralogy of Fallot: surgical versus percutaneous treatment

Annals of Translational Medicine (2020)

Juan Antonio Meca Aguirrezabalaga Jacobo Silva Guisasola Rocío Díaz Méndez Alain Eliott Escalera Veizaga Daniel Hernández-Vaquero Panizo

: Pulmonary regurgitation is the most important sequellae after correction of Tetralogy of Fallot and has a considerable impact over the right ventricle. Surgery has demonstrated low early mortality after pulmonary valve replacement and good long-term outcomes, remaining nowadays the gold standard treatment of pulmonary regurgitation in rTOF patients. Nevertheless, transcatheter pulmonary valve implantation has emerged as a new, safe and efficient alternative to surgical valve replacement. In this review article, we try to evaluate and compare both techniques to find out which is the best therapeutic option in this patients.

Pulmonary Valve Insufficiency

Pulmonary valve

Gold standard (test)

Valve replacement

10.21037/atm.2020.03.81

Cite

Citations (10)

Cambios morfológicos anulares tras reparación mitral transcatéter: repercusión clínica y relevancia de la etiología

Alberto Alperi Isaac Pascual Víctor León Remigio Padrón Encalada Iria Silva Conde

espanolIntroduccion y objetivos: La insuficiencia mitral es una de las enfermedades valvulares mas prevalentes en nuestro medio. La reparacion mitral transcateter con el sistema MitraClip es un procedimiento cada vez mas utilizado en este contexto. Los objetivos del estudio fueron evaluar los cambios morfologicos anulares, la recurrencia de la insuficiencia mitral significativa y un objetivo combinado de reingreso por insuficiencia cardiaca y mortalidad global. Metodos: Estudio prospectivo, observacional y unicentrico. Se incluyeron pacientes tratados con reparacion mitral transcateter entre octubre de 2015 y octubre de 2018. Se realizo un analisis tridimensional del anillo con el software de cuantificacion mitral MVQ QLAB 10.0 (Philips; Amsterdam, Paises Bajos). Resultados: Se realizaron 50 procedimientos en 48 pacientes. Tras el procedimiento se observo una disminucion significativa de ambos diametros anulares, asi como del perimetro y del area, y una mayor reduccion del diametro anteroposterior en los pacientes con insuficiencia mitral funcional con respecto a aquellos con insuficiencia mitral organica (13,2 ± 8,8 frente a 8,6 ± 7,5; p = 0,05). El porcentaje de grasping sobre el velo posterior fue el unico parametro que se asocio estadisticamente a una menor probabilidad de desarrollar insuficiencia mitral significativa (OR = 0,89; IC95%, 0,79-0,98). Conclusiones: Tras el implante de MitraClip se producen cambios morfologicos en el anillo mitral. La magnitud de estos cambios es diferente segun la etiologia de la insuficiencia mitral. El grasping del velo posterior es el principal factor asociado a dichos cambios y previene la recurrencia de la insuficiencia mitral significativa. EnglishIntroduction and objectives: Mitral regurgitation is one society’s most prevalent valvular diseases. Transcatheter mitral valve repair with the MitraClip system has become more widely used for the management of this condition. The endpoints of the study were the changes in the mitral annular morphology, the recurrent grade III-IV mitral valve regurgitation, and a composite endpoing of heart failure readmission and all-cause mortality. Methods: Single-centre, prospective and observational study. We included patients admitted due to transcatheter mitral valve repair between October 2015 and October 2018. The three-dimensional analysis of the mitral valve annulus was performed using the MVQ QLAB mitral valve quantification software (Philips; Amsterdam, The Netherlands). Results: Fifty procedures were performed on 48 patients. A significant decrease of both annular diameters, perimeter and area was observed after the procedure. The antero-posterior diameter reduction was more significant in patients with functional mitral regurgitation compared to patients with organic mitral regurgitation (13.2 ± 8.8 vs 8.6 ± 7.5; P = .05). The posterior leaflet grasping was the only parameter associated with less chances of significant recurrent mitral regurgitation (OR = 0.89; 95CI%, 0.79-0.98). Conclusions: Mitral annular morphological changes occur after MitraClip implantation. The magnitude of these changes varies depending on the etiology of mitral regurgitation. Posterior leaflet grasping is the main factor associated with these changes and prevents the recurrence of significant mitral regurgitation.

MitraClip

Source

Cite

Citations (0)

Transcatheter aortic valve implantation for the treatment of degenerated mitroflow bioprosthesis

European Heart Journal (2020)

Marcel Almendárez Lacayo Rut Álvarez Velasco Daniel Hernández-Vaquero Panizo Porfirio Fernández A Adeba García

Abstract Introduction The leading cause of valvular heart replacement therapy is symptomatic aortic stenosis (AS). The Mitroflow (MF) bovine pericardial prosthesis is prone to early structural valve deterioration (SVD) and has been used in over 100,000 patients for the treatment of symptomatic AS. The standard of care for degenerated bioprosthesis is surgical aortic valve replacement. However, valve-in-valve transcatheter aortic valve replacement (VIV-TAVI) is an interesting therapeutic modality currently being evaluated to avoid redo surgery. Purpose The purpose of this study was to evaluate the clinical outcomes of patients with SVD MF bioprosthesis treated with VIV-TAVI. Methods Data was collected from all the patients undergoing TAVI in a single center from March 2012 to July 2019. All the cases remitted for VIV-TAVI were prospectively included and followed. All events were classified according to the VARC-2 definitions. The primary endpoints were a combination of clinical events at the end of the follow-up which included all-cause mortality, cardiovascular mortality, hospitalizations due to heart failure and stroke/transient ischemic attack. Secondary endpoints were absence of SVD and valve hemodynamics at the end of the follow-up. Results Between march 2012 and July 2019, 65 patients were derived for VIV-TAVI. The mean age was 80,4±5.93 years. 50,8% were male. The average STS score was 6.39±5,62 and Euroscore II 8.86±5.17. All the patients were diagnosed with SVD with a mixed mechanism (stenosis/regurgitation) being the most frequent form of disfunction (38,5%) followed by regurgitation (33,9%) and stenosis (27,7%). Procedural success was achieved in 98,5% of the cases, there were 2 deaths of cardiovascular origin, 1 stroke, and 2 hospitalizations due to heart failure. The mean gradient, peak gradient and valve area at discharge were 13,3mmHg, 27,2mmHg and 1,14cm2, respectively. After 28,8 months (17,4–60,9) of follow-up the combined endpoint occurred in 21 patients (32,3%). There was a total of 13 deaths (20%) and only 4 (7.3%) from cardiovascular causes. 2 patients were reported of having a stroke/TIA and there were 5 readmissions from heart failure (2 of them within the first 30 days). The mean gradient, peak gradient and valve area remained steady when comparing post-TAVI vs follow-up, 20.3mmHg vs 18.8mmHg (p=0.2), 39.6mmHg vs 35.2mmHg (p=0.01) and 1.3cm2 vs 1.3cm2 (p=0.7), respectively. The same tendency was observed in aortic regurgitation. There were no significant changes in the LVEF over time. There were only 2 patients (3.1%) presenting with valve deterioration during follow-up. Conclusions VIV-TAVI for SVD MF bioprosthesis is a safe procedure and a valid alternative to surgery in this group patients, with a high rate of success and low intraprocedural complications. At 28 months of follow-up, 68% of patients were free of late clinical events and valve hemodynamics maintain over time. Figure 1 Funding Acknowledgement Type of funding source: None

EuroSCORE

Stroke

Valve replacement

10.1093/ehjci/ehaa946.1937

Cite

Citations (0)

Influencia de la circulación extracorpórea en el sangrado postoperatorio y en los concentrados de hematíes transfundidos en cirugía de revascularización miocárdica en grupos de alto riesgo

Daniel Hernández-Vaquero Panizo

INTRODUCCION Y OBJETIVOS: la influencia de la cirugia sin circulacion extracorporea en el sangrado postoperatorio y en los concentrados de hematies transfundidos en pacientes con elevado riesgo de sangrado es desconocida. Nuestro objetivo radica en conocerla. METODOS: se estudiaron todos los pacientes intervenidos de cirugia de revascularizacion miocardica aislada con caracter electivo en nuestro centro desde enero de 2007 hasta septiembre de 2010. Se crearon cuatro grupos de pacientes documentados bibliograficamente como de elevado riesgo de sangrado: pacientes con insuficiencia renal, edad >75 anos, menor superficie corporal y menor indice de masa corporal. Se estudio la influencia de la cirugia sin circulacion extracorporea en el sangrado postoperatorio y los concentrados de hematies transfundidos en cada uno mediante un analisis ajustado por Propensity Score. RESULTADOS: la cirugia sin circulacion extracorporea redujo el sangrado postoperatorio (CR=-256,41; p=0,039) y los concentrados de hematies transfundidos (CR=? 0,66; p=0,027) en los 138 pacientes con unos niveles preoperatorios de creatinina>1,2mg/dl. Mientras que en los 120 pacientes>75 anos, no influyo en ninguna de las dos variables, en los grupos tercero y cuarto si redujo los concentrados de hematies transfundidos (CR=-1,11; p 75 anos no se beneficiaron. Los pacientes con menor superficie corporal y menor indice de masa corporal redujeron los concentrados de hematies transfundidos sin disminuir el sangrado postoperatorio lo que probablemente se deba a una menor hemodilucion.

Source

Cite

Citations (0)

Satisfacción del alumnado en la utilización de sus teléfonos móviles como herramienta de gamificación en un entorno universitario

Aula de Encuentro (2024)

Daniel Hernández-Vaquero Panizo Isaac Pascual Alberto Domínguez‐Rodríguez Rebeca Lorca Gutiérrez Miguel Muñiz‐Calvente

The use of the mobile phone as a gamification tool to improve attention and interest in a university context has been barely evaluated. The objective of this study is to evaluate it in some subjects of the Medicine and Biology degree. The experiment was carried out in three highly demanding and rote learning subjects of the Degree in Medicine and Biology at the University of Oviedo. After each lesson, the researchers devoted 8 minutes to carry out game-based quizzes through mobile phones. The students' satisfaction with the technique was evaluated at the end of the subject. The statistics used are descriptive together with histograms. The results were encouraging, with more than 90% of the students wanting to use the methodology in the rest of the subjects and more than 90% also having a high degree of overall satisfaction. The results were highly concordant in the three subjects analysed despite their technical diversity.

10.17561/ae.v26n1.7791

Cite

Citations (0)

Cirugía en la miocardiopatía hipertrófica obstructiva. Resultados a 10 años

Cirugía Cardiovascular (2018)

Rubén A. Cabo Carlota Vigil-Escalera Alain Escalera J.J.R. Reguero Blanca Meana Fernández

10.1016/j.circv.2018.07.003

Cite

Citations (0)

40. Esperanza de vida de octogenarios operados de recambio valvular por estenosis aórtica grave. Comparación con la población general. Clase funcional y predictores independientes de mortalidad a largo plazo

Cirugía Cardiovascular (2010)

Daniel Hernández-Vaquero Panizo Juan C. Llosa David Calvo Carlos Morales J.L. Naya

Realizar un seguimiento a largo plazo de los pacientes con más de 80 años operados mediante cirugía convencional de recambio valvular aórtico por estenosis grave. Estudiamos a todos los pacientes de más de 80 años operados de recambio valvular aórtico por estenosis grave en nuestro centro desde 1996-2006 (104 pacientes), realizándose un seguimiento medio de 51,33 meses. Analizamos su esperanza de vida media y la comparamos con la de la población general de la misma edad, el estado funcional y los predictores independientes de mortalidad durante el seguimiento. La supervivencia a 1, 2, 3, 5, 7 y 10 años desde la operación fue del 90,4 ± 2,9%, 80,8 ± 3,9%, 76,9 ± 4,1%, 65,7 ± 5,1%, 49,4 ± 6,7%, 29 ± 9,2%, respectivamente. La media de supervivencia fue de 81,4 ± 6,6 meses (6,78 años), igualando prácticamente a la que el Instituto Nacional de Estadística (INE) estima para la población general de la misma edad (7,5 años). El 91,5% de los pacientes se encontraron durante el seguimiento en grado funcional de la New York Heart Association (NYAH) I-II/IV. Los factores que se comportaron como predictores independientes de mortalidad fueron los niveles preoperatorios de creatinina (p = 0,01), la cirugía urgente por estado crítico (p = 0,004) y la arteriopatía extracardíaca (p = 0,005). En nuestro centro, los pacientes con más de 80 años a los que se realizó recambio valvular por estenosis aórtica grave mediante cirugía convencional tuvieron una supervivencia media que iguala prácticamente a la que el INE otorga para la población general de la misma edad. Estos pacientes gozaron a largo plazo de un excelente grado funcional.

10.1016/s1134-0096(10)70690-2

Cite

Citations (0)