Zhaleh Shadman

Tehran University of Medical Sciences

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Bagher Larijani

Tehran University of Medical Sciences

Mohsen Khoshniat Nikoo

Tehran University of Medical Sciences

Mahdieh Akhoundan

National Nutrition and Food Technology Research Institute

Farshad Sharifi

Tehran University of Medical Sciences

Moloud Payab

Tehran University of Medical Sciences

Nooshin Poorsoltan

Tehran University of Medical Sciences

Mahbube Ebrahimpur

Tehran University of Medical Sciences

Gita Shafiee

Tehran University of Medical Sciences

Afshin Ostovar

Tehran University of Medical Sciences

Iraj Nabipour

Bushehr University of Medical Sciences

Cooperative Institutions

Tehran University of Medical Sciences

Shahid Beheshti University of Medical Sciences

Shariati Hospital

University of Tehran

Iran University of Medical Sciences

Research Institute for Endocrine Sciences

National Nutrition and Food Technology Research Institute

Shahid Beheshti University

Bushehr University of Medical Sciences

Isfahan University of Medical Sciences

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Quality of reporting of randomized controlled trials of herbal medicines conducted in metabolic disorders in Middle East countries: A systematic review

Complementary Therapies in Medicine (2018)

Ozra Tabatabaei‐Malazy Zhaleh Shadman Hanieh‐Sadat Ejtahed Rasha Atlasi Mohammad Abdollahi

10.1016/j.ctim.2018.04.004

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Citations (14)

Dynapenia-abdominal obesity and mortality risk, is independent effect obscured by age and frailty?:Birjand Longitudinal Aging Study (BLAS)

Journal of Diabetes & Metabolic Disorders (2024)

Mansoureh Ashghali Farahani Farshad Sharifi Moloud Payab Zhaleh Shadman Hossein Fakhrzadeh

Abdominal obesity

Longitudinal Study

Univariate analysis

10.1007/s40200-024-01501-8

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Citations (0)

DOAJ (DOAJ: Directory of Open Access Journals) (2015)

Zhaleh Shadman Mehdi Hedayati Bagher Larijani Mahdieh Akhoundan M Khoshniat

Ramadan fasting is specific intermittent fasting comprising significant changes in routine lifestyle pattern and may affect body homeostasis and metabolism. In spite of several studies conducted on the effects of Ramadan fasting on various aspects of health and disease, because of heterogeneity in methodology and procedures (sometimes inevitable), a comprehensive concluding for reliable results as in most conditions is impossible. Based on basic studies and those have been conducted in this field, this paper suggests a checklist contains, as far as possible, important factors to be considered in designing, interpreting and comparing the results of Ramadan fasting studies. Accordingly, circadian rhythm, season/latitude sensitivity, serum osmolarity and, lifestyle changes (including dietary intakes, physical activity, sleep quality and duration, smoking and, etc.) may be of great importance. Also, a close definition of the number of fasting days and it consecutively or alternatively must be presented with reference to sex. Appropriate time points for blood/urine sampling would be varied case by case.

Guideline

Intermittent Fasting

Affect

10.22038/jfh.2015.6247

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Citations (3)

Effect of Therapeutic Dose of Vitamin D on Serum Adiponectin and Glycemia in Vitamin D-Insufficient or Deficient Type 2 Diabetic patients

Iranian Red Crescent Medical Journal (2014)

Nima Baziar Kurosh Jafarian Zhaleh Shadman Mostafa Qorbani Mohsen Khoshniat Nikoo

Background: Lower vitamin D status has been reported in diabetic patients.Serum 25-hydroxyvitamin D and adiponectin were inversely associated with type 2 diabetes and insulin resistance.Vitamin D may involve in regulation of the adiponectin levels, which is directly related to insulin sensitivity.Objectives: The aim of this study was to investigate the effect of therapeutic dose of vitamin D on serum adiponectin and insulin resistance in vitamin D-insufficient or deficient type 2 diabetic patients.Materials and Methods: This double-blind, randomized, clinical trial was conducted on 81 type 2 diabetic patients with vitamin D level of 10-30 ng/mL.Intervention was 50000 IU vitamin D or placebo once a week for 8 weeks.At the beginning and end of the study, blood samples were collected after 12 hours of fasting and serum glucose, insulin, 25-hydroxyvitamin D, and adiponectin were measured.Insulin resistance was calculated by homeostasis model assessment (HOMA-IR).Results: After 8-week intervention, serum 25-hydroxyvitamin D significantly increased and reached the normal levels in patients receiving vitamin D (P < 0.001) and the levels of fasting serum glucose, insulin, and HOMA-IR were significantly decreased (P = 0.04, 0.02 and 0.007, respectively).No significant changes were observed in these levels in the placebo group.Significant differences were observed in mean changes in the above-mentioned variables between the two groups (P = 0.01, 0.04 and 0.006, respectively).No significant changes were found in serum adiponectin in the vitamin D and placebo groups (P = 0.83).Conclusions: Therapeutic dose of vitamin D can improve vitamin D status and glycemic indicators.But it seems that an 8-week intervention period was not sufficient to reveal the possible effects of vitamin D on serum adiponectin levels.

10.5812/ircmj.21458

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Citations (32)

Nutritional Education Needs in Relation to Ramadan Fasting and Its Complications in Tehran, Iran

Iranian Red Crescent Medical Journal (2016)

Zhaleh Shadman Mahdieh Akhoundan Nooshin Poorsoltan Mohsen Khoshniat Nikoo Bagher Larijani

Ramadan fasting is associated with some lifestyle changes. A lack of nutritional needs knowledge or the improper performance of fasting, particularly in relation to time, type and amount of food intake, can cause disorders such as indigestion, bloating, constipation, headaches and other clinical problems.To investigate the general knowledge regarding dietary factors associated with Ramadan fasting and its related complications.This prospective, non-interventional, observational study was conducted from April to July, 2012 to coincide with the month before and the month of Ramadan. The initial participants were 600 fasting and 588 non-fasting people (aged 18 - 65 years, BMI 18.5 - 40 kg/m2) chosen by random cluster sampling in Tehran, Iran. A questionnaire of Ramadan fasting nutritional knowledge was developed and validated in a pilot study. The Likert scale was used two weeks before Ramadan and during the third and fourth weeks of Ramadan to estimate Ramadan-related complications. Seven-day, 24 - hour food recalls were used to assess food intakes.The lowest level of general knowledge was identified in the context of foods associated with hunger (22.1%) and hypoglycemia (24.8%) and the highest level of general knowledge was identified in reference to unsuitable foods for Sahar (91.4%). During Ramadan, all attributed complications increased in fasting subjects (P < 0.001). High calorie, carbohydrate, fat and protein intakes in the Ramadan diet were associated with some gastrointestinal and sleep complications (P < 0.05).Despite the relatively high level of knowledge in the context of the general principles of a diet to prevent Ramadan-related complications, practical training in regard to the amounts of nutrients associated with Ramadan-related complications is both necessary and recommended.

Indigestion

Bloating

10.5812/ircmj.26130

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Citations (9)

New challenges in dietary pattern analysis: combined dietary patterns and calorie adjusted factor analysis in type 2 diabetic patients

Journal of Diabetes & Metabolic Disorders (2014)

Zhaleh Shadman Mahdieh Akhoundan Nooshin Poorsoltan Bagher Larijani Mostafa Qorbani

Some variability for dietary pattern analysis due to subjective procedures (e.g. arbitrary food categorization and number of factors extraction) was reported. The aim of this study was to present or design a new approach to challenge the conventional dietary pattern analysis through new classification of dietary patterns according to the possibility of the high adherence to more than one dietary pattern and calorie adjusted factor extracting.This cross-sectional study conducted on 734 type2 diabetic patients. Factor analysis defined three major dietary patterns (Western like, Asian like and Traditional like) and the associations of each pattern were assessed with glycemic control and lipid profiles among tertiles of each pattern. In order to compare variables in highest tertile of three defined dietary patterns, eight new different groups were classified according to the high adherence to one or more patterns and ANOVA and ANCOVA were used to compare them. Also, calorie adjusted factor extracting were done to find out if the same factor loadings would be extract.Among three major dietary patterns, only Western like showed a significant association with fasting blood sugar (p = 0.03, 12.49 ± 5.99), serum total cholesterol (p = 0.02, 8.71 ± 3.81) and LDL cholesterol (p = 0.04, 5.04 ± 2.40). While comparison of new classified patterns, showed no significant differences, except a high blood glucose in Western like- Asian like versus traditional like dietary pattern (p = 0.04). Also, calorie adjusted factor extracting showed different factor loadings.Results showed that the conventional dietary pattern analysis method may have substantial limitations in interpreting the results and may lead to inappropriate conclusions.

10.1186/2251-6581-13-71

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Citations (6)

Misconceptions and negative attitudes towards the metabolic effects of Ramadan fasting, resulting in fasting avoidance

DOAJ (DOAJ: Directory of Open Access Journals) (2014)

Zhaleh Shadman Nooshin Poorsoltan Mahdieh Akhoundan Bagher Larijani Camellia Akhgar Zhand

The aim of this study was to assess public knowledge about the effects of Ramadan fasting on various aspects of health and its association with fasting decision-making. This cross-sectional study was conducted on 600 subjects. The association between fasting and participants’ knowledge and attitudes toward Ramadan fasting, anthropometric measurements, physical activity, depression, anxiety, stress, dietary intake, and prior history of diseases was evaluated. The results indicated an adverse correlation between negative attitudes towards the effects of Ramadan fasting and adherence to fasting (P<0.0001). The prevalence of gastrointestinal disorders was higher in the non-fasting group (P=0.002). No significant association was found between other investigated variables and fasting adherence. It seems that negative thinking about the effects of Ramadan fasting may be inversely associated with fasting decision-making. Therefore, evidence-based educational programs may improve public knowledge and encourage fasting among eligible people.

Depression

Intermittent Fasting

Association (psychology)

10.22038/jfh.2014.3682

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Citations (0)

Evaluation of the prevalence of cardiometabolic disorders (diabetes, hypertension, and hyperlipidemia) diagnosed, undiagnosed, treated, and treatment goal in the elderly: Bushehr Elderly Health Program (BEH)

BMC Endocrine Disorders (2024)

Mahbube Ebrahimpur Erfan Mohammadi-Vajari Yasaman Sharifi Leila Ghotbi Masoumeh Sarvari

Abstract As the population ages, the global burden of cardiometabolic disorders will increase. This study aimed to investigate the prevalence of cardiometabolic disorders (diabetes, hypertension, and hyperlipidemia) in elderly and to evaluate the effects of various variables including age, sex, education, marital status, smoking, income, physical activity, dementia and depressed mood on untreated cardiometabolic disorders. This was a cross sectional study conducted in Bushehr Elderly Health Program. A total 2381 participants were included. Medical data were collected by trained interviewers. The mean age of the study participants was 69.34 years. Proportions of diabetes, hypertension, hyperlipidemia and hypercholesterolemia were 43.25%, 75.71%, 64.74% and 35.31% respectively. Untreated diabetes prevalence was higher for males (OR = 1.60, 95%CI = 1.20–2.15), older adults (OR = 1.02, 95%CI = 1.00–1.05), and pre-frail status (OR = 0.69, 95%CI = 0.52–0.92). Males (OR = 2.16, 95%CI = 1.64–2.84) and current smokers (OR = 1.42, 95%CI = 1.05–1.93), in contrast to married participants (OR = 0.25, 95%CI = 0.08–0.78), people with higher education levels (OR = 0.51, 95%CI = 0.29–0.89) and dementia (OR = 0.78, 95%CI = 0.61–1.00) were more likely to have untreated HTN. Untreated dyslipidemia is more common in smokers (OR = 1.78, 95%CI = 1.19–2.66) and males (OR = 1.66, 95%CI = 1.21–2.27), while untreated hypercholesteremia is more common in males (OR = 3.20, 95%CI = 1.53–6.69) and is reported lower in people with dementia (OR = 0.53, 95%CI = 0.28–1.01).

Dyslipidemia

Hyperlipidemia

Marital status

Cross-sectional study

10.1186/s12902-024-01561-0

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Citations (1)

Ramadan fasting, pregnancy and lactation

Iranian South Medical Journal (2014)

Mohsen Khoshniat Nikoo Zhaleh Shadman Bagher Larijani

Source

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Citations (2)

Effect of conjugated linoleic acid and vitamin E on glycemic control, body composition, and inflammatory markers in overweight type2 diabetics

Journal of Diabetes & Metabolic Disorders (2013)

Zhaleh Shadman Forough Azam Taleban Navid Saadat Mehdi Hedayati

The healthy properties of conjugated linoleic acid (CLA) such as weight loss, reducing cardiovascular risk factors and inflammation have been reported. The trans-10, cis-12 CLA isomer is related to increasing insulin resistance, but the effects of cis-9, trans-11 isomer is not clear. The aim of this study was to investigate the effects of CLA with and without Vitamin E on body weight, body composition, glycemic index, inflammatory and coagulation factors, lipid profile, serum leptin and adiponectin, malondialdehyde (MDA), and blood pressure in type2 diabetes.56 patients with type2 diabetes were included in 8 week double-blind control trial that used metformin. They randomly divided into three groups: CLA + VitE, CLA + VitE placebo, CLA placebo + VitE placebo. All variables, anthropometric measurements, and body composition were evaluated at the beginning and the end of study. Statistical analysis and analysis of dietary data were performed using SPSS and nutritionist IV software, respectively.There were not any significant differences in variable changes among three groups. However, there was a trend to increase in MDA and decrease in apoB100 among CLA consumers.The results of this study showed that administration of CLA supplementation for 8 weeks does not affect any indicators of metabolic control in overweight type2 diabetic patients.

Lipid Profile

Malondialdehyde

10.1186/2251-6581-12-42

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Citations (37)