Reem Jan

University of Chicago

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Simon Hong

NYU Langone Health

Joerg Ermann

Brigham and Women's Hospital

Andrew Stahly

University of Colorado Anschutz Medical Campus

Bahar Moghaddam

Icahn School of Medicine at Mount Sinai

John M. Davis

Mayo Clinic in Arizona

Rahul S. Dalal

Brigham and Women's Hospital

Kristine A. Kuhn

University of Colorado Anschutz Medical Campus

Alexa Silfen

University of Chicago

Fardina Malik

NYU Langone Health

Frank I. Scott

University of Colorado Anschutz Medical Campus

Cooperative Institutions

University of Chicago

National Institutes of Health

National Human Genome Research Institute

University of Chicago Medical Center

Stanford University

Center for Rheumatology

University of Michigan–Ann Arbor

Johns Hopkins University

Scleroderma Foundation

National Institute of Arthritis and Musculoskeletal and Skin Diseases

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S41 Case Report: Immunoglobulin G4-Related Disease Mistaken for Crohn’s Disease

The American Journal of Gastroenterology (2023)

Emma A. Picker Reem Jan Christopher R. Weber Lindsay Yassan John Hart

10.14309/01.ajg.0000995904.06419.f0

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Examining spondyloarthritis in patients with inflammatory bowel disease

Proceedings of IMPRS (2020)

Catherine M. Burns Reem Jan

Background/Objective: Axial spondyloarthritis refers to a syndrome of inflammatory back pain associated with radiographic or magnetic resonance imaging abnormalities. Peripheral spondyloarthritis can include dactylitis, enthesitis or oligo-arthritis. Together these encompass common extra-gastrointestinal manifestations of inflammatory bowel disease (IBD), with the prevalence of ankylosing spondylitis estimated to be about 3% in patients with IBD and unspecified sacroiliitis occurring in 10%. The goals of this study are to validate the accuracy of the Toronto Axial Spondyloarthritis Questionnaire in identifying patients with rheumatologic symptoms in the context of IBD, to re-evaluate the prevalence of spondyloarthritis in this population, and to identify any differences in referral rate between racial and ethnic groups. Methods: Patients were selected based on the following criteria: diagnosis of IBD, upcoming appointment with their gastroenterologist, prior consent in the Genesys database and access to an operational MyChart account. Patients were sent a link and asked to complete a RedCap survey modified from the Toronto Axial Spondyloarthritis Questionnaire. Positive patient responses will be analyzed in a follow-up visit with a rheumatologist to investigate the patients’ symptoms. Results: At present, the survey was sent to 86 patients with 26 respondents completing the survey. Of the respondents, 6 patients had experienced back pain for a duration of 3 months or longer. Eleven patients had pain and swelling of a joint unrelated to injury. Seven patients experienced pain and swelling of an entire finger or toe unrelated to injury. Seven patients experienced heel pain unrelated to injury. One patient is followed by rheumatology. Conclusion/Potential Impact: Major extra gastrointestinal manifestations of IBD include axial or peripheral spondyloarthritis which can lead to disabling back pain and/ or joint disease. With the modified Toronto Axial Spondyloarthritis Questionnaire, gastroenterologists could have a better way to identify concerning symptoms, leading to increased referral to rheumatologists and potential changes in treatment plans.

Inflammatory Bowel Diseases

10.18060/24548

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JCR Journal of Clinical Rheumatology (2020)

Josh Waytz Reem Jan

University of Chicago Medicine, Chicago, IL [email protected]. The authors declare no conflict of interest.

Hypophysitis

10.1097/rhu.0000000000001624

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Approach to Patients with Suspected Rheumatic Disease

Primary Care Clinics in Office Practice (2018)

Iaszmin Ventura Pankti Reid Reem Jan

Rheumatic disease

Dry mouth

Signs and symptoms

10.1016/j.pop.2018.02.001

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Rheumatoid Arthritis and Sjogren's Disease

CRC Press eBooks (2024)

Michael J. Cammarata Reem Jan

10.1201/9781003367307-3

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Sa1829 IDENTIFYING PREDICTORS OF INFLAMMATORY MUSCULOSKELETAL SYMPTOMS AND SPONDYLOARTHRITIS IN A MULTICENTER COHORT OF PATIENTS WITH IBD

Gastroenterology (2024)

Simon Hong Rahul S. Dalal Kristine A. Kuhn Andrew Stahly Frank I. Scott

Axial spondyloarthritis

10.1016/s0016-5085(24)01714-1

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Management of Gout

JAMA (2021)

Irsk Anderson Andrew M. Davis Reem Jan

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal

10.1001/jama.2021.19763

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Fibromyalgia

Oxford University Press eBooks (2018)

Reem Jan Dawen Zhang

Fibromyalgia is caused by abnormal central pain processing, but it is often dismissed as a psychiatric or functional disorder. Perimenopausal women are most commonly affected, but the incidence in men has been underestimated. Patients present with diffuse musculoskeletal pain and frequently have sleep disturbances, fatigue, and somatic complaints. In 2010, the American College of Rheumatology removed the need for a standardized tender point examination. The disease is often misdiagnosed given its nonspecific complaints and heterogeneous presentation. Laboratory testing is used only to rule out differential diagnoses. Treatment is challenging and a multidisciplinary approach, including patient counseling and education, a graded exercise program, and pharmacologic treatment, is recommended.

10.1093/med/9780190271787.003.0038

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Frequency of Spondyloarthritis Symptoms Among U.S. Patients with Inflammatory Bowel Disease: A Cross‐sectional Multi‐Center Study

Arthritis Care & Research (2025)

Joerg Ermann Simon Hong Andrew Stahly Rahul S. Dalal Fardina Malik

Objective Spondyloarthritis (SpA) is the most common extraintestinal manifestation of inflammatory bowel disease (IBD). The application of screening tools to detect SpA in patients with IBD may lead to earlier recognition of SpA and affect treatment decisions. Methods A combination of two previously described SpA screening questionnaires, DETAIL and IBIS‐Q, was administered to consecutive patients with IBD attending IBD specialty clinics in six U.S. academic medical centers. Demographic data, IBD and rheumatology history were extracted by chart review. Results A total of 669 patients were analyzed. The median age was 40 years (IQR 30 ‐ 54) with a median disease duration of 12 years (IQR 6 ‐ 22) and moderate to severe IBD based on medication exposure and history of bowel surgery. 81 patients (12%) carried a diagnosis of an inflammatory rheumatic disease while 75 (11%) had consulted a rheumatologist during the previous year. Using published cutoffs, 180 out of 669 patients (27%) screened positive with DETAIL, 266 (40%) with IBIS‐Q and 275 (41%) with either questionnaire. Axial symptoms were more frequently reported than peripheral musculoskeletal complaints. Notably, 189 out of 275 (69%) screen‐positive patients, had neither a documented inflammatory rheumatic disease diagnosis nor a visit with a rheumatologist within the past year. Conclusion A substantial proportion of patients with IBD have symptoms suggestive of SpA, and many of these may have undiagnosed SpA. The IBIS‐Q questionnaire appears to identify more potential SpA cases than DETAIL. Strategies are needed to prioritize rheumatology consultations for those patients with IBD who are most likely to benefit.

Specialty

Cross-sectional study

Medical History

10.1002/acr.25493

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Role of the Use of Omental Flap in Prognosis of Cases with Induced Acute Pancreatitis in Experimental Dogs

JOP, journal of the pancreas (2016)

Mohamed S. Hassan Nader Shaaban Ashraf M. Abu‐Seida Mostafa M. Khodeir Reem Jan

Aim Acute pancreatitis frequently involves peripancreatic tissues and remote organ systems resulting in severe complications and high risk of mortality. Therefore, the present study was carried out to assess the effect of omental flap as a new treatment of acute pancreatitis. Methods Ten mongrel dogs with experimentally induced acute pancreatitis were randomly divided into two equal groups; treated and control groups. The pancreas was wrapped with omental flap in the treated group and the pancreas was left without treatment in control group. Urea, Creatinine, lactate dehydrogenase, serum Amylase, Ca, and C-reactive protein were measured in all dogs before surgery and 2 hours, 3 days, 7 days, and 4 weeks post-surgery. Weekly ultrasound examination was performed post-surgery. Exploratory laparotomy was carried out 45 days post-surgery, all findings were reported and pancreatic biopsies were collected and prepared for histopathological examination using Schmidt Scoring system. Data were displayed as the mean ± SD and SPSS was used. Statistical significance (at P < 0.05) was calculated by χ2 test. Results There was a significant difference between the two groups in favor of the treated group as regards levels of lactate dehydrogenase, ultrasonographic findings, pathological findings and Schmidt scoring. Conclusion Omental flap can be used as a new minimally invasive effective technique for treatment of acute pancreatitis.

Exploratory laparotomy

Kowsar

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