Farnaz Jafarpour

University of Tehran

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Hooshang Pirelahi

University of Tehran

Mehdi Khoobi

Tehran University of Medical Sciences

Hamideh Hazrati

University of Tehran

Abbas Shafiee

University of Queensland

Mehran Ghasemi

University of Nizwa

Ghasem Rezanejade Bardajee

Shahid Beheshti University

Nafiseh Jalalimanesh

University of Tehran

Alireza Foroumadi

Tehran University of Medical Sciences

Maryam Dehghan

University of Tehran

Samaneh Zarei

Université de Montréal

Cooperative Institutions

University of Tehran

Tehran University of Medical Sciences

Tabriz University of Medical Sciences

University of Tabriz

Payame Noor University

Shahid Beheshti University

University of Toronto

K.N.Toosi University of Technology

University of Zanjan

Pharmaceutical Sciences Research Center

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CCDC 2248038: Experimental Crystal Structure Determination

The Cambridge Structural Database (2023)

Mehran Ghasemi Banafshe Rahimi Maryam Dehghan Mohammad Hossein Bernoosha Farnaz Jafarpour

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/ccdc.csd.cc2fg8ck

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ChemInform Abstract: Palladium/Norbornene Catalysis: A Versatile Aryl C—H Hydroxyalkylation, Alkyl Cinnamate Formation.

ChemInform (2013)

Farnaz Jafarpour Nafiseh Jalalimanesh

Abstract Acrylates and aliphatic alcohols are appropriate reagents in palladium‐catalyzed, norbornene‐mediated domino ortho‐alkylation/Heck reactions.

Norbornene

10.1002/chin.201319073

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Polyoxygenated cinnamoylcoumarins as conformationally constrained analogs of cytotoxic diarylpentanoids: Synthesis and biological activity

European Journal of Medicinal Chemistry (2013)

Fatemeh Molaverdi Mehdi Khoobi Saeed Emami Masoumeh Alipour Omidreza Firuzi

K562 cells

MTT assay

Thiol

IC50

Viability assay

Jurkat cells

10.1016/j.ejmech.2013.07.014

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Citations (24)

CCDC 290732: Experimental Crystal Structure Determination

The Cambridge Structural Database (2006)

Farnaz Jafarpour Hooshang Pirelahi

10.5517/cc9rjg0

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CCDC 272690: Experimental Crystal Structure Determination

The Cambridge Structural Database (2005)

Farnaz Jafarpour Hooshang Pirelahi

10.5517/cc94rgm

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Assembly of Indole Cores through a Palladium-Catalyzed Metathesis of Ar–X σ-Bonds

Organic Letters (2020)

Farnaz Jafarpour Mehran Ghasemi Hamed Navid Niloofar Safaie Saideh Rajai‐Daryasarei

We describe the development of a new method for construction of highly substituted indole scaffolds through the strategic utilizing of the metathesis of Ar-X σ-bonds based on the dynamic nature of palladium-based oxidative addition/reductive elimination. A suitable and simple catalytic system has provided an appropriate platform for a productive ligand exchange and consecutive carbopalladation/C–H activation/amination of phosphine ligands with alkynes and aromatic/aliphatic amines for construction of structurally diverse indoles.

Salt metathesis reaction

Reductive elimination

Oxidative addition

10.1021/acs.orglett.0c03611

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Citations (12)

DTBP-mediated controlled oxidative C–S bond cleavage/annulation cascade: construction of indenones

New Journal of Chemistry (2023)

Farnaz Jafarpour Banafshe Rahimi

The cascade involves the controlled formation of carbonyls from benzyl thioethers followed by the annulation of alkynes to offer privileged indenone skeletons.

Annulation

Oxidative cleavage

Cleavage (geology)

Bond cleavage

10.1039/d2nj06286k

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Citations (1)

ChemInform Abstract: Domino o‐Alkylation and Heteroarylation of Iodoarenes: One‐Pot Synthesis of Benzocyclohepta[b]indoles.

ChemInform (2013)

Farnaz Jafarpour Asieh Otaredi‐Kashani Saeideh Behpajooh

Abstract Various derivatives of the medicinally interesting heterocyclic scaffold are prepared which, in part, include substituents for further functionalization.

Domino

10.1002/chin.201331128

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Synthesis and Anticholinergic Activity of 4‐hydroxycoumarin Derivatives Containing Substituted Benzyl‐1,2,3‐triazole Moiety

Chemical Biology & Drug Design (2015)

Sahar Bagheri Mehdi Khoobi Hamid Nadri Alireza Moradi Saeed Emami

A series of 4‐hydroxycoumarin‐derived compounds 8a‐p containing N ‐benzyl‐1,2,3‐triazole motif were designed as AC hE inhibitors. The title compounds were obtained conveniently using multicomponent click reaction. The in vitro anticholinesterase evaluation of synthesized compounds against AC hE and BuChE showed that some of them are potent and selective inhibitors of AC hE. Among them, 2‐chlorobenzyl derivative 8k showed the most potent activity against AC hE ( IC 50 = 0.18 μ m ). Its activity was also superior to that of standard drug tacrine. The kinetic study and molecular docking simulation of the most potent compound 8k were also described.

Tacrine

Moiety

Triazole

1,2,3-Triazole

Docking (animal)

4-Hydroxycoumarin

10.1111/cbdd.12588

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Citations (47)

Crystal structures of cis- and trans-4-benzyl-4-methyl 2,6-diphenyl-4H-thiopyran-1-oxide, C25H22OS

Zeitschrift für Kristallographie - New Crystal Structures (2005)

Farnaz Jafarpour Hooshang Pirelahi

Article Crystal structures of cis- and trans-4-benzyl-4-methyl 2,6-diphenyl-4H-thiopyran-1-oxide, C25H22OS was published on April 1, 2005 in the journal Zeitschrift für Kristallographie - New Crystal Structures (volume 220, issue 1-4).

Thiopyran

Crystal (programming language)

10.1524/ncrs.2005.220.14.440

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