Marc Blondon

This update describes contemporary studies of clinical relevance in angiology and hemostasis. We discuss newer developments for the treatment of haemophilia, with a focus on drugs with longer-half lives. Direct anticoagulants (DOAC: rivaroxaban, apixaban, edoxaban and dabigatran) and their approved prescription in Switzerland are summarized, with a description of antidotes that will be available in the near future. We will present new data on the utility of cancer screening at the diagnosis of idiopathic venous thromboembolism (VTE) and on the evaluation of DOAC in patients with cancer-related VTE. Finally, new studies evaluating the clinical risk-benefit of anticoagulation bridging for patients with vitamin K antagonists undergoing procedures do not support the use of such bridging in the majority of patients.

Edoxaban

Apixaban

Angiology

Vitamin K antagonist

Acenocoumarol

Source

Cite

Citations (0)

Angiologie et hémostase

Revue Médicale Suisse (2016)

Françoise Boehlen Marc Blondon Pierre Fontana

Several themes were selected from those that marked the year 2016. The analysis of registries with «real life» data regarding the use of direct oral anticoagulants is reassuring and overall confirm the data of the pivotal studies. We also present the validation of a prediction rule for risk stratification of thromboembolism recurrence and duration of anticoagulation after an unprovoked event. In addition, new data shed light on the treatment of distal vein thrombosis. We also address the issue of venous thromboembolism risk related to oral contraceptives and the issue of genetic testing prior prescription, and finally present a new factor VIII recently available for the treatment of patients with acquired hemophilia A.

Risk Stratification

10.53738/revmed.2016.12.500-01.0013

Cite

Citations (1)

Monitoring white blood cell count in adult patients with schizophrenia who are taking clozapine: a cost-effectiveness analysis

The Lancet Psychiatry (2014)

François Girardin Antoine Poncet Marc Blondon Victoria Rollason Nathalie Vernaz

White blood cell

Therapeutic Drug Monitoring

10.1016/s2215-0366(14)70245-7

Cite

Citations (24)

High-flow arteriovenous fistula resulting from stingray injury

Journal of Travel Medicine (2022)

Ilaria Bologna Marine Baumberger Marc Blondon Nicolas Mürith Sigiriya Aebischer-Perone

Stingray punctures are relatively common in several coastal regions and may result in chronic wounds and disability due to injury and envenomation. Vascular complications are rare but can be severe. We describe a case of high-flow arteriovenous fistula resulting from a stingray injury that required a venous bypass.

Stingray

10.1093/jtm/taac098

Cite

Citations (0)

SERUM 25-HYDROXYVITAMIN D AND PARATHYROID HORMONE LEVELS DO NOT PREDICT CHANGES IN CAROTID ARTERIAL STIFFNESS AFTER 10 YEARS: THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS

Journal of the American College of Cardiology (2014)

Adam D. Gepner Laura A. Colangelo Marc Blondon Claudia E. Korcarz Ian H. de Boer

10.1016/s0735-1097(14)62134-3

Cite

Citations (1)

Fondaparinux for Isolated Superficial Vein Thrombosis of the Legs: A Cost-Effectiveness Analysis

Journal of Vascular Surgery (2012)