Fengzhong Wang

Institute of Food Science and Technology

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Bei Fan

Chinese Academy of Agricultural Sciences

121

Li‐Tao Tong

Institute of Food Science and Technology

H. Eugene Stanley

Boston University

Aixia Wang

Inner Mongolia University

Yatao Huang

Chinese Academy of Agricultural Sciences

Lili Wang

Dalian University

Liya Liu

Chinese Academy of Agricultural Sciences

Mengzi Nie

Institute of Food Science and Technology

Shlomo Havlin

Bar-Ilan University

Xinmin Liu

Chinese Academy of Medical Sciences & Peking Union Medical College

Cooperative Institutions

Chinese Academy of Agricultural Sciences

349

Institute of Food Science and Technology

314

Ministry of Agriculture and Rural Affairs

196

Chinese Academy of Sciences

109

Institute of Agro-Products Processing Science and Technology

Zhejiang University

Chinese Academy of Medical Sciences & Peking Union Medical College

Northeast Agricultural University

University of Chinese Academy of Sciences

Tsinghua University

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Review on Chemical Structures and Biological Activities of Spermidine Derivatives in Plants

Journal of Nuclear Agricultural Sciences (2018)

Shuo Zhao Xing Cencan Wang Yan Ran Suo Fengzhong Wang

10.11869/j.issn.100-8551.2018.01.0123

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Citations (1)

Edible qualities, microbial compositions and volatile compounds in fresh fermented rice noodles fermented with different starter cultures

Food Research International (2022)

Aixia Wang Tianzhen Xiao Huihan Xi Wanyu Qin Yue He

Starter

Lactobacillus fermentum

Fermentation starter

10.1016/j.foodres.2022.111184

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Citations (19)

Therapeutic Effects of <i>Hemerocallis citrina</i> Baroni Extract on Animal Models of Neurodegenerative Diseases Through Serotonin and HLH-30/TFEB Dependent Mechanisms

Jorge H. Fernandes Marta D. Costa Daniela Vilasboas-Campos Joana Pereira-Sousa Bruna Ferreira-Lomba

Hemerocallis citrina is an herbaceous perennial plant used in Asian cuisine and in Traditional Chinese Medicine. Here, we tested the therapeutic potential for a extracts (HCE30%, HCE50% and HCN) in vivo, using models of two human genetic neurodegenerative diseases – Machado-Joseph Disease/Spinocerebellar Ataxia type 3 and Frontotemporal Dementia with Parkinsonism associated to chromosome 17. Chronic treatment with HCE30% extract ameliorated the motor deficits typically observed in these models. Interestingly, we found that the effect on the motor phenotype of the MJD/SCA3 model was dependent on serotonergic signalling and on the action of the HLH-30/TFEB transcription factor, known to regulate the cellular response to amino acid starvation, the autophagy and mitophagy pathways, lysosome localization and biogenesis, exocytosis and mitochondrial biogenesis. Altogether, our findings reinforce the idea that phytochemicals act through the modulation of serotonergic neurotransmission and introduce a novel layer to the HLH-30/TFEB regulatory network. Thus, also strengthen the use of these pathways as therapeutic targets for protein-related neurodegenerative disorders and confirm the utility of medicinal plants as a source of innovation, in the quest for new therapeutic agents.

TFEB

10.20944/preprints202501.2306.v1

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Editorial: Innovative high value-added processing of soybean and its by-products

Frontiers in Nutrition (2023)

Bo Lyu Fengzhong Wang Yang Li Siew Young Quek Hansong Yu

EDITORIAL article Front. Nutr., 27 June 2023Sec. Nutrition and Food Science Technology Volume 10 - 2023 | https://doi.org/10.3389/fnut.2023.1240249

10.3389/fnut.2023.1240249

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Epigenetics and Cellular Metabolism

Genetics & Epigenetics (2016)

Wenyi Xu Fengzhong Wang Zhongsheng Yu Fengjiao Xin

Living eukaryotic systems evolve delicate cellular mechanisms for responding to various environmental signals. Among them, epigenetic machinery (DNA methylation, histone modifications, microRNAs, etc.) is the hub in transducing external stimuli into transcriptional response. Emerging evidence reveals the concept that epigenetic signatures are essential for the proper maintenance of cellular metabolism. On the other hand, the metabolite, a main environmental input, can also influence the processing of epigenetic memory. Here, we summarize the recent research progress in the epigenetic regulation of cellular metabolism and discuss how the dysfunction of epigenetic machineries influences the development of metabolic disorders such as diabetes and obesity; then, we focus on discussing the notion that manipulating metabolites, the fuel of cell metabolism, can function as a strategy for interfering epigenetic machinery and its related disease progression as well.

Cellular metabolism

10.4137/geg.s32160

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Citations (51)

Role of exogenous melatonin in table grapes: First evidence on contribution to the phenolics-oriented response

Food Chemistry (2020)

Lei Wang Zisheng Luo Mingyi Yang Dong Li Ming Qi

Phenylalanine ammonia-lyase

10.1016/j.foodchem.2020.127155

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Citations (67)

Effects of unsaturated C18 fatty acids on “glucose-glutathione” Maillard reaction: Comparison and formation pathways of initial stage and meaty flavor compounds

Food Research International (2024)

Wenbin Du Qianli Ma Yang Li Shuang Bai Yatao Huang

10.1016/j.foodres.2024.115645

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Analysis on Inner Structural Optimization Design for a New Certain Maintenance Fittings Carrying Vehicle

Vehicle & Power Technology (2006)

Fengzhong Wang

The inner structural optimization design for a new certain maintenance fittings carrying vehicle was analyzed.The aim of the optimization design is to solve the contradiction between inner storage space of van body and structure deadweight and maneuverability of vehicle.The maintenance fittings carried was evaluated by statistic analysis method,and the inner storage space and structure optimization designs were carried out by the use of the software ANSYS.The demand of maintenance fittings carried and structure deadweight were met by the design scheme.

Optimal design

Statistic

Source

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Antimicrobial activity and comparative metabolomic analysis of Priestia megaterium strains derived from potato and dendrobium

Scientific Reports (2023)

Jiameng Liu Yan-Tian Liang Shanshan Wang Nuo Jin Jing Sun

Abstract The growth of endophytic bacteria is influenced by the host plants and their secondary metabolites and activities. In this study, P. megaterium P-NA14 and P. megaterium D-HT207 were isolated from potato tuber and dendrobium stem respectively. They were both identified as Priestia megaterium . The antimicrobial activities and metabolites of both strains were explored. For antimicrobial activities, results showed that P. megaterium P-NA14 exhibited a stronger inhibition effect on the pathogen of dendrobium, while P. megaterium D-HT207 exhibited a stronger inhibition effect on the pathogen of potato. The supernatant of P. megaterium P-NA14 showed an inhibition effect only on Staphylococcus aureus , while the sediment of P. megaterium D-HT207 showed an inhibition effect only on Escherichia coli . For metabolomic analysis, the content of L -phenylalanine in P. megaterium P-NA14 was higher than that of P. megaterium D-HT207, and several key downstream metabolites of L -phenylalanine were associated with inhibition of S. aureus including tyrosine, capsaicin, etc. Therefore, we speculated that the different antimicrobial activities between P. megaterium P-NA14 and P. megaterium D-HT207 were possibly related to the content of L -phenylalanine and its metabolites. This study preliminarily explored why the same strains isolated from different hosts exhibit different activities from the perspective of metabolomics.

Bacillus megaterium

10.1038/s41598-023-32337-6

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Citations (11)

Optimization of Sporulation Conditions for Bacillus subtilis BSNK-5

Processes (2022)

Zhiliang Tian Lizhen Hou Miao Hu Yaxin Gao Danfeng Li

Bacillus subtilis spores have important biological applications; however, high spore-cell densities and sporulation efficiencies in fermentation is poorly reported. This study systematically analyzed the spore densities and formation efficiency of B. subtilis BSNK-5 in different culture substrates. A response surface regression equation was established based on the results of single factor and Box–Behnken experimental designs. The optimal medium formulation, as predicted from the equation, consisted of soluble starch at 3 g·L−1, soybean flour at 12 g·L−1, and MgSO4 at 5 g·L−1. The spore yield reached 2.43 × 109 CFU·mL−1, and the sporulation rate was 83.3%, which was nearly three times higher than before optimization using an optimized medium at 36 °C and 200 rpm for 60 h.

10.3390/pr10061133

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Citations (9)