Supplementary Figure 1 shows the approach for rapid magnetic bead based separation of OT-1 cells and peptide pulsed splenocytes for metabolomic analysis.

Splenocyte

10.1158/2159-8290.24792919

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Supplementary Figure 2 from Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade

Jared H. Rowe Ilaria Elia Osmaan Shahid Emily F. Gaudiano Natalia E. Sifnugel

Supplementary Figure 2 shows the one carbon enzyme expression levels and serine biosynthesis following activation of CD8+ T cells with varying concentrations of anti-CD3.

10.1158/2159-8290.24792895.v1

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Supplementary Figure 3 from Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade

Jared H. Rowe Ilaria Elia Osmaan Shahid Emily F. Gaudiano Natalia E. Sifnugel

Supplementary Figure 3 shows the cytotoxicity of previously activated CD8+ T cells with or without the SHMT inhibitor.

10.1158/2159-8290.24792892.v1

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Anti-Programmed Death 1 (PD1)

Springer eBooks (2013)

Gordon J. Freeman Arlene H. Sharpe

10.1007/978-1-4614-6613-0_39-2

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Supplementary Figure 15 from Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade

Jared H. Rowe Ilaria Elia Osmaan Shahid Emily F. Gaudiano Natalia E. Sifnugel

Supplementary Figure 15 shows the effects of formate treatment on TCF1 and TIM3 expression in tumor infiltrating "bystander cells."

Bystander effect

10.1158/2159-8290.24792898.v1

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Supplemental Table 2 from Differential Expression of PD-L1 between Primary and Metastatic Sites in Clear-Cell Renal Cell Carcinoma

Marcella Callea Laurence Albigès Mamta Gupta Su‐Chun Cheng Elizabeth M. Genega

PD-L1 positivity in relation to tumor grade within individual lesions.

Primary (astronomy)

Table (database)

Expression (computer science)

10.1158/2326-6066.22538789

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Figure S3 from Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer

Nicolás A. Giraldo Étienne Becht Franck Pagès Georgios Skliris Virginie Verkarre

Figure S3. Representative IHC staining of immune checkpoints in ccRCC : Immunohistochemical staining of immune checkpoints on sections from paraffin embedded ccRCC tumors illustrating highly and poorly PD-1 (A) and LAG-3 (B) infiltrated lesions and PD-L1 (C) and PD-L2 (D) positive and negative tumors

10.1158/1078-0432.22457633

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Table S4 from Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer

Nicolás A. Giraldo Étienne Becht Franck Pagès Georgios Skliris Virginie Verkarre

Table S4. Univariate Cox regression analysis for OS and DFS in primary and metastatic ccRCC. P-values and HR of significant variables are highlighted in bold font.

Univariate

Univariate analysis

Table (database)

10.1158/1078-0432.22457618.v1

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