Mayumi Mitani

National Cerebral and Cardiovascular Center

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Kunio Miyatake

National Cerebral and Cardiovascular Center

Shintaro Beppu

Aichi Cancer Center

Masahiro Yasaka

National Kyushu Medical Center

Takenori Yamaguchi

National Cerebral and Cardiovascular Center

Seiki Nagata

Kansai Rosai Hospital

Hiromi Seo

Japanese Circulation Society

Jun Tamai

Keio University

Satoshi Nakatani

Saiseikaisenri Hospital

Teruo Omae

National Cerebral and Cardiovascular Center

Masakazu Yamagishi

Toyama College

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National Cerebral and Cardiovascular Center

Osaka University

Kyoto University

Japanese Circulation Society

Kansai Rosai Hospital

Kyushu University

National Kyushu Medical Center

Osaka Minami Medical Center

National Hospital Organization

Tokushima University

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Consequence of Diseases in Aorta on Evaluation of Aortic Regurgitation by Aortic Flow Velocity Profiles

Angiology (1994)

Mayumi Mitani Jun Tamai Kunio Miyatake

The aim of the study was to investigate whether flow velocity profiles of the aorta are related to the severity of aortic valve regurgitation (AR) in patients with diseases of the aorta. Aortic root angiography, abdominal aortic flow velocity measurements by pulsed Doppler method, and regurgitant jet measurements by color Doppler echocardiography were performed in 62 patients with various etiologies of AR and 13 patients without AR. The regurgitant fraction of abdominal aortic flow velocity profiles was related to the angiographic severity of AR except for the patients with Takayasu's arteritis and those after thoracic aorta grafting who showed large regurgitant fraction regardless of AR. Color Doppler evaluation was also correlated well with angiographic findings, but it was not possible in 13 of 62 patients with AR because of the inadequate color Doppler images. Although the observation of abdominal aortic flow profiles is clinically of value in nonin vasive evaluation of AR, it could not be applied in patients with Takayasu's arteritis and those after graft surgery.

Regurgitant fraction

Abdominal aorta

Aortography

10.1177/000331979404500704

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Citations (3)

Prediction of embolism in patient with mitral stenosis studied by two-dimensional echocardiography and blood coagulation tests.

Nihon Naika Gakkai Zasshi (1989)

Masahiro Yasaka Kunio Miyatake Mayumi Mitani Shintaro Beppu Seiki Nagata

僧帽弁狭窄症例中,塞栓症の既往や心内血栓を有する例(易塞栓群)とそれらを有さない例(非易塞栓群)の間に,凝固線溶能に差があるか否かを明らかにするため,健常者10例と僧帽弁狭窄症48例に断層心エコー図検査と凝血学的検査を行った。易塞栓群ではfibrinopeptide A (FPA), firinopeptide Bβ 15-42 (FPBβ 15-42), D-dimer (DD)が健常者や非易塞栓群に比し有意に高値を示した.さらに可動性血栓を有する例ではDDが他に比し,著しい高値(300ng/ml以上)を示した,以上からFPA, FPBβ 15-42およびDDは易塞栓群抽出に有用で,特にDDは塞栓源として非常に危険な可動性血栓群で著しい高値を示すことから,塞栓症発症の予知につながる重要な指標と考えられる.

10.2169/naika.78.1736

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Citations (1)

Intracardiac mobile thrombus and D-dimer fragment of fibrin in patients with mitral stenosis.

Heart (1991)

Masahiro Yasaka Kunio Miyatake Mayumi Mitani Shintaro Beppu Shigekazu Nagata

OBJECTIVE--To investigate the relation between intracardiac thrombus and blood coagulability in patients with mitral stenosis. DESIGN--Prospective study. Cross sectional echocardiography and plasma concentrations of the D-dimer fragment of fibrin were used concurrently to detect intracardiac thrombus in patients with mitral stenosis. SETTING--Department of Medicine, National Cardiovascular Centre, Osaka, Japan. PATIENTS--63 patients with mitral stenosis. None of them had been receiving any anticoagulants or antiplatelet agents. MAIN OUTCOME MEASURES--Plasma concentrations of D-dimer in patients with a mobile intracardiac thrombus, those in patients with a non-mobile intracardiac thrombus, and those in patients without an intracardiac thrombus. RESULTS--A mobile intracardiac thrombus was found in 10 patients and a non-mobile thrombus in eight. The remaining 45 patients had no intracardiac thrombi. Plasma concentrations of D-dimer in the 10 patients with a mobile thrombus were all greater than 300 ng/ml (mean 983.3, 95% confidence interval 498.9 to 1467.7 ng/ml) and they were significantly higher than those in the patients with a non-mobile thrombus (226.2, 33.6 to 418.8 ng/ml) and the patients without an intracardiac thrombus (147.2, 110.4 to 184 ng/ml). CONCLUSIONS--A high plasma concentration of D-dimer seemed to reflect a hypercoagulable intracardiac state and may be a helpful indicator of the possible presence of mobile intracardiac thrombus in patients with mitral stenosis.

10.1136/hrt.66.1.22

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Citations (47)

Application of Doppler color flow imaging to determine valve area in mitral stenosis

Journal of the American College of Cardiology (1991)

Takehiko Kawhara Masakazu Yamagishi Hiromi Seo Mayumi Mitani Satoshi Nakatani

Cardiac catheterization

Color doppler

Mitral valve stenosis

10.1016/s0735-1097(10)80223-2

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Citations (38)