José M. Enríquez–Navascués

Biogipuzkoa Health Research Institute

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Co-Authors

Carlos Placer

Biogipuzkoa Health Research Institute

Eloy Espín

Universitat Autònoma de Barcelona

Sebastiano Biondo

South University

José Luis Elósegui

Biogipuzkoa Health Research Institute

Nerea Borda

Biogipuzkoa Health Research Institute

Ignacio Aguirre–Allende

Biogipuzkoa Health Research Institute

Yolanda Saralegui

Biogipuzkoa Health Research Institute

Eduardo García‐Granero

South University

Luís Bujanda

Biogipuzkoa Health Research Institute

Antonio Codina Cazador

Clínica Girona

Cooperative Institutions

University of Birmingham

1,192

St James's University Hospital

666

University of Leeds

660

University of Southampton

257

Southampton General Hospital

234

NIHR Birmingham Biomedical Research Centre

234

Institut de Virologie

224

University College London

209

University of Edinburgh

186

Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie

168

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Meckel's diverticulum adenocarcinoma: a rare malignant degeneration.

PubMed (2003)

X Martín José Luis Elorza Orúe M J Busto Vicente I Irureta Urreatavizcaya R Jiménez Aguero

The case of a 40 year old male that, after the etiological study performed due to rectorrhages that was the only symptom he presented, was referred to an exploratory laparotomy. A disseminated adenocarcinoma arising in Meckeĺs diverticulum was detected and palliative segmentary resection of the small bowel was performed. The lack of previous symptoms lead to the dissemination of the disease and to the impossibility of curative surgical resection of the tumor.

Exploratory laparotomy

Etiology

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Citations (7)

Duodenal Crohn's disease – gastro‐jejunal bypass versus duodenal–jejunal bypass – a video vignette

Colorectal Disease (2020)

Garazi Elorza-Echaniz Ignacio Aguirre–Allende Nerea Borda-Arrizabalaga Emma Eizaguirre-Letamendia José M. Enríquez–Navascués

Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Vignette

Gastro-

10.1111/codi.15202

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Citations (0)

Predictive Markers of Coagulopathy in COVID-19 Infection: A Meta Narrative Review

Arili A. Bedoy Adriana L. Chapa José M. Enríquez–Navascués Christy C. Saquin Uyen N. Tran

In late 2019, COVID was initially discovered in Wuhan, China, and the COVID-19 pandemic primarily began in early 2020. Along with respiratory distress, COVID-19 patients had an increased risk of forming abnormal clotting. In ICU COVID-19 patients, abnormal clotting increases the risk of mortality by approximately 74% (Montiel et al., 2022). The aim for this meta-narrative review was to identify what hemostatic parameters are predictive of coagulopathy in COVID-19 patients. Determining predictive markers of coagulopathy in COVID-19 infection may allow for early identification of severe cases before bleeding and thrombotic manifestations occur. The review included articles primarily from PubMed and were published between 2020 and 2022. After screening for eligibility, seven articles were deemed fit to be included. Our findings indicate that elevated D-dimer levels were the most common predictive hemostatic parameter utilized, along with elevated Von Willebrand Factor, elevated Factor VIII, and decreased fibrinogen levels. COVID-19 patients that presented with these parameters upon admission were highly likely to experience clotting events such as deep vein thrombosis and pulmonary embolism. Although many of the articles in this review focused on elevated D-dimer as an early marker of coagulopathy, one study found that elevated soluble thrombomodulin was the best predictor of coagulopathy in COVID patients. Future research will be needed to confirm soluble thrombomodulin’s ability as a predictive parameter and compare its suggestive power to D-dimer levels. Clinical trials will also be needed to assess how these predictive markers can be used to inform prophylactic treatment in COVID-19 patients.

Clotting factor

Thrombomodulin

10.52519/00114

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Citations (0)

Características fenotípicas de los pacientes con síndrome de poliposis serrada de colon: estudio de 23 casos

Cirugía Española (2014)

Garazi Elorza José M. Enríquez–Navascués Luís Bujanda Mikel Larzábal Inés Gil Lasa

Polypectomy

10.1016/j.ciresp.2014.02.005

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Citations (3)

Variabilidad interhospitalaria de la dehiscencia anastomótica en el Proyecto del Cáncer de Recto de la Asociación Española de Cirujanos: La influencia del volumen quirúrgico

Cirugía Española (2016)

Héctor Ortiz Sebastiano Biondo Antonio Codina Cazador M. A. Ciga José M. Enríquez–Navascués

Stoma (medicine)

10.1016/j.ciresp.2015.11.008

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Citations (13)

Type and Consequences of Short-Term Complications in Colon Cancer Surgery, Focusing on the Oldest Old

Clinical Colorectal Cancer (2019)

Marisa Baré Laura Mora Miguél Pera P Collera Maximino Redondo

10.1016/j.clcc.2019.11.003

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Citations (9)

The Use of Seton as a Bridge to Definitive Ligation of the Intersphincteric Fistula Tract Procedure for Fistula-in-ano: A Systematic Review and Meta-analysis

Journal of Coloproctology (2021)

Carlos Placer–Galán José M. Enríquez–Navascués Tania Pastor-Bonel Ignacio Aguirre–Allende Yolanda Saralegui-Ansorena

Abstract Background There is still controversy over the usefulness of seton placement prior to the ligation of the intersphincteric fistula tract (LIFT) surgery in the management of anal fistula. Objective To evaluate the impact of preoperative seton placement on the outcomes of LIFT surgery for the management of fistula-in-ano. Design systematic review and meta-analysis. Data Sources A search was performed on the MEDLINE (PubMed), EMBASE, Scopus, Web of Science, Cochrane Library and Google Scholar databases. Study Selection Original studies without language restriction reporting the primary healing rates with and without seton placement as a bridge to definitive LIFT surgery were included. Intervention The intervention assessed was the LIFT with and without prior seton placement. Main Outcome Measures The main outcome was defined as the primary healing rate with and without the use of seton as a bridge to definitive LIFT surgery. Results Ten studies met the criteria for systematic review, all retrospective, with a pooled study population of 772 patients. There were no significant differences in the percentages of recurrence between patients with and without seton placement (odds ratio [OR] 1.02; 95% confidence interval [CI] 0.73–1.43: p = 0.35). The I2 value was 9%, which shows the homogeneity of the results among the analyzed studies. The 10 included studies demonstrated a weighted average overall recurrence of 38% (interquartile range [IQR] 27–42.7%), recurrence with the use of seton was 40% (IQR 26.6–51.2%), and without its use, the recurrence rate was 51.3% (IQR 31.3–51.3%) Limitations The levels of evidence found in the available literature were relatively fair, as indicated after qualitative evaluation using the Newcastle-Ottawa scale and the Attitude Heading Reference System (AHRS) evidence levels. Conclusions Our meta-analysis suggests that the placement of seton as a bridge treatment prior to LIFT surgery does not significantly improve long-term anal fistula healing outcomes. Ligation of the intersphincteric fistula tract surgery can be performed safely and effectively with no previous seton placement. International prospective register of systematic reviews—PROSPERO registration number: CDR42020149173.

Interquartile range

Fistulotomy

10.1055/s-0041-1730039

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Citations (3)

La respuesta inicial al diltiazem tópico puede predecir la evolución de la fisura anal crónica

Cirugía Española (2007)

Carlos Placer José Luis Elósegui Idoia Irureta José Andrés Mujika I Goena

10.1016/s0009-739x(07)71655-x

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Citations (13)

Invasive and non-invasive extramammary perianal Paget's disease: Understanding of carcinogenesis determines individualized treatment