M C Deabate

Ospedale Martini

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F Quarello

University of Turin

Cesare Guarena

Gruppo Italiano per il Trapianto di Midollo Osseo

R Boero

Istituto di Fisiologia Clinica

C Rosati

Agence de la Biomédecine

Giuseppe Piccoli

IRCCS Eugenio Medea

T Fidelio

CTO Hospital

C. Licata

Fondazione Ricerca Molinette

Barbara Rolando

University of Turin

G Iacono

University of Campania "Luigi Vanvitelli"

G.P. Sancipriano

University of Turin

Cooperative Institutions

University of Turin

Società Italiana di Nefrologia

Azienda Ospedaliero Universitaria San Giovanni Battista

Fondazione Ricerca Molinette

Ospedale San Giovanni Bosco

CTO Hospital

Ospedale Civile Di Ivrea

Institute of Nephro Urology

Ospedale Martini

Azienda Ospedaliera Citta' della Salute e della Scienza di Torino

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Erythrocyte Na+, K+ pump inhibition after saline infusion in essentially hypertensive subjects: effects of canrenone administration

International Journal of Cardiology (1989)

R Boero Cesare Guarena M C Deabate Barbara Rolando C Rosati

10.1016/0167-5273(89)90092-2

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Citations (12)

In vitro effects of verapamil and methoxy-verapamil [D 600] on transmembrane sodium and potassium transport in human erythrocytes.

PubMed (1985)

Cesare Guarena R Boero F Quarello C Rosati M C Deabate

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Canrenone Prevents Na,K Pump Inhibition Induced by Volume Expansion in Normal Subjects

Springer eBooks (1987)

R Boero Cesare Guarena F Quarello C Rosati Barbara Rolando

Active metabolite

10.1007/978-1-4613-2067-8_12

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Citations (1)

Optimizing Sodium Balance in Hemodialysis

Blood Purification (1996)

G.P. Sancipriano Alessandro Negro C. Amateis V. Calitri Francesca Cantone

this paper develops and tests a mathematical model for Na+ kinetics applied to standard hemodialysis. The volume of distribution of exchangeable Na+, dialyzer surface area, blood and dialysis fluid flow rate, target weight loss, treatment duration and the Na+ diffusibility constant are taken into account. The model is used to compute the optimal hour by hour dialysis fluid Na+ concentration required to achieve the prescribed end-dialysis natremia and maintain a constant end-dialysis body Na+ pool, while providing a nearly uniform removal of Na+ over dialysis. The model was preliminary tested on 10 consecutive dialyses in a single patient using special dialyzer which generates a part of ultrafiltrate uncontaminated by dialysate.

Body fluid

10.1159/000170253

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Citations (7)

Erythrocyte Na,K pump activity and arterial hypertension in uremic dialyzed patients

Kidney International (1988)

R Boero Cesare Guarena I.M. Berto M C Deabate C Rosati

Efflux

Sodium pump

Essential hypertension

10.1038/ki.1988.234

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Citations (17)

A case of persistent iron deficiency anemia in a kidney transplant recipient

Digestive and Liver Disease (2020)

M. Sacco Mauro Bruno M C Deabate C.G. De Angelis Marco Pennazio

Fecal occult blood

10.1016/j.dld.2020.03.025

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Citations (1)

[Evolution of the serum aluminum values in the Piedmont dialysis population. Dialysis Centers of the Piedmont].

PubMed (1994)

T Fidelio C. Licata Assumpta Serra B Scalzo M C Deabate

The authors have evaluated the evolution of values of serum aluminium concentration (Als) in the whole pool of patients undergoing RDT in Piedmont in the years 1982-1990. We have compared the data of the Piedmont Regional Registry of Dialysis and Transplantation at the end of 1990 to those obtained in 1982, 1986 and 1989. A progressive reduction has been observed in the percentage of patients with Als > 100 micrograms/l, who were 13.5% of the pool in 1982 and 7.5% in 1986 and finally decreased to 1.5% in 1990. This is yet more evident for patients dialyzing at home as in 1982 43% of them had a Als > 100 micrograms/l, whereas in 1986 only 8.2% did and in 1990 this percentage had decreased to 3.6%. The values of Als (distinguished by type of treatment of chronic renal failure) show end confirm the improvement of the situation of aluminium accumulation, specially as regards bicarbonate HD where the percentage of patients with Als > 100 micrograms/l decreases from 10.5% in 1986 to 1.7% in 1990. These data point out the efficacy of prevention and control programs regarding aluminium pathology performed in the last years in Piedmont. This has led to a reduction of the severe accumulation syndromes observed in the first years of '80 and has allowed the nephrologist to prepare more correct therapeutic prescriptions.

Nephrology

Chronic renal failure

Bicarbonate

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Red Blood Cell Na<sup>+</sup>, K<sup>+</sup> Pump Activity in Patients on Hemofiltration

Blood Purification (1984)

F Quarello R Boero Cesare Guarena C Rosati M C Deabate

The intracellular concentration of Na+ ([Na+i]) and the Na+ efflux mediated by the Na+, K+ pump were evaluated in red blood cells from 9 patients on hemofiltration, 8 on hemodialysis, 9 on continuous ambulatory peritoneal dialysis (CAPD) and 12 normal subjects. [Na+i] was elevated in CAPD patients only. The rate constant for pump-mediated sodium efflux was close to normal in hemofiltration patients, and significantly reduced in hemodialysis (p < 0.03) and CAPD (p < 0.01) patients. Uremic plasma from subjects on hemodialysis and CAPD, but not from hemofiltration, significantly (p < 0.001) inhibited the Na+, K+ pump activity of normal red blood cells. Among our uremic patients those on hemofiltration showed a red blood cell Na+, K+ pump activity close to that of normal subjects, possibly related to the absence in their plasma of a circulating pump inhibitor, that seems invariably present in plasma from hemodialysis and CAPD patients.

Hemofiltration

Efflux

Sodium pump

10.1159/000169324

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Citations (2)

[Regular dialysis treatment of chronic uremia caused by polycystic kidney].

PubMed (1985)

Pierpaolo Piccoli F Quarello Cesare Guarena Federica Bonello M C Deabate

Uremia

Dialysis Therapy

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