Edmond P. Wickham

Virginia Commonwealth University

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Ronald K. Evans

Virginia Commonwealth University

Melanie K. Bean

Children's Hospital of Richmond at VCU

John E. Nestler

European Gravitational Observatory

Marilyn Stern

University of South Florida

Suzanne E. Mazzeo

Virginia Commonwealth University

Jessica Gokee LaRose

Virginia Commonwealth University

R. Lee Franco

Virginia Commonwealth University

Mary K. Bowen

Virginia Commonwealth University

Daphne Bryan

Florida College

Jerome F. Strauss

University of Pennsylvania

Cooperative Institutions

Virginia Commonwealth University

Children's Hospital of Richmond at VCU

Virginia Commonwealth University Medical Center

University Health System

University of Pennsylvania

Interfaith Medical Center

University of Virginia

Johns Hopkins University

National Institutes of Health

Johns Hopkins Medicine

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Motivational Interviewing in Health Care: Results of a Brief Training in Endocrinology

Journal of Graduate Medical Education (2012)

Melanie K. Bean Diane M. Biskobing Gary L. Francis Edmond P. Wickham

Despite the importance of lifestyle change in disease management and the growing evidence supporting motivational interviewing (MI) as an effective counseling method to promote behavioral change, to date there are few published reports about MI training in graduate medical education.The study aimed to pilot the feasibility and effectiveness of a brief MI training intervention for endocrinology fellows and other providers.We used a pretest/posttest design to evaluate a brief MI training for 5 endocrinology fellows and 9 other providers. All participants completed subjective assessments of perceived confidence and beliefs about behavioral counseling at pretest and posttest. Objective assessment of MI was conducted using fellows' audiotaped patient encounters, which were coded using a validated tool for adherence to MI before and after the training. Paired t tests examined changes in objective and subjective assessments.The training intervention was well received and feasible in the endocrinology setting. At posttest, participants reported increased endorsement of the MI spirit and improved confidence in MI skills. Objective assessment revealed relative improvements in MI skills across several domains. However, most domains, as assessed by a validated tool, did not reach competency level after the training intervention.Although more intensive training may be needed to develop MI competence, the results of our pilot study suggest that brief, targeted MI training has short-term efficacy and is well received by endocrinology fellows and other providers.

Motivational Interviewing

Brief intervention

10.4300/jgme-d-11-00166.1

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Citations (12)

Total and high–molecular weight adiponectin in women with the polycystic ovary syndrome

Metabolism (2010)

Edmond P. Wickham Kai I. Cheang John N. Clore Jean-Patrice Baillargeon John E. Nestler

10.1016/j.metabol.2010.02.019

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Citations (40)

A scalable, virtual weight management program tailored for adults with type 2 diabetes: effects on glycemic control

Nutrition and Diabetes (2023)

John W. Apolzan Jessica Gokee LaRose Stephen D. Anton Robbie A. Beyl Frank L. Greenway

Abstract Background The objective was to test the efficacy of a scalable, virtually delivered, diabetes-tailored weight management program on glycemic control in adults with type 2 diabetes (T2D). Methods This was a single arm, three-site clinical trial. Participants had baseline HbA1c between 7–11% and BMI between 27–50 kg/m 2 . Primary outcome was change in HbA1c at 24 weeks. Secondary outcomes were changes in body weight, waist circumference, the Diabetes Distress Scale (DDS), quality of life (IWQOL-L), and hunger (VAS). Generalized linear effects models were used for statistical analysis. Results Participants ( n = 136) were 56.8 ± 0.8 y (Mean ± SEM), 36.9 ± 0.5 kg/m 2 , 80.2% female, 62.2% non-Hispanic white. Baseline HbA1c, weight, and total DDS score were 8.0 ± 0.09%, 101.10 ± 1.47 kg, and 2.35 ± 0.08, respectively. At week 24, HbA1c, body weight, and total DDS decreased by 0.75 ± 0.11%, 5.74 ± 0.50%, 0.33 ± 0.10 units, respectively (all p < 0.001). Also, at week 24, quality of life increased by 9.0 ± 1.2 units and hunger decreased by 14.3 ± 2.4 units, (both p < 0.0001). Conclusions The scalable, virtually delivered T2D-tailored weight management program had favorable and clinically meaningful effects on glycemic control, body weight, and psychosocial outcomes.

Weight management

10.1038/s41387-023-00234-6

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Citations (4)

Prevalence of the Metabolic Syndrome Among Obese Adolescents Enrolled in a Multidisciplinary Weight Management Program: Clinical Correlates and Response to Treatment

Metabolic Syndrome and Related Disorders (2009)

Edmond P. Wickham Marilyn Stern Ronald K. Evans Daphne Bryan William B. Moskowitz

The aim of this study was to determine the prevalence of the metabolic syndrome at baseline and after 6 months of lifestyle modification among obese adolescents referred to a multidisciplinary weight management program.A total of 165 obese adolescents were evaluated at baseline, and measurements were repeated in 57 subjects who completed 6 months of the program. Metabolic syndrome was defined as having three or more of the following: a body mass index (BMI) >97(th) percentile, hypertension, low high-density lipoprotein cholesterol (HDL-C), hypertriglyceridemia, and impaired fasting glucose (IFG).The prevalence of a BMI >97(th) percentile, hypertension, hypertriglyceridemia, low HDL-C, and IFG was 92.7, 54.5, 29.1, 26.7, and 2.4%, respectively. The prevalence of the metabolic syndrome at baseline was 30.3%. After 6 months of lifestyle modification, BMI z scores, percent body fat, total cholesterol, and low-density lipoprotein cholesterol (LDL-C) decreased significantly from baseline; however, there was no significant change in the number of subjects demonstrating >or=three criteria of the metabolic syndrome.Approximately one third of the study subjects met the criteria of the metabolic syndrome, emphasizing the growing concern for the future development of premature cardiovascular disease in this high-risk population. Our data suggest that new strategies for lifestyle modification may be needed to improve cardiovascular risk factors significantly among adolescents with obesity.

Weight management

10.1089/met.2008.0038

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Citations (56)

Pediatric Health Care Provider Perceptions of Weight Loss Surgery in Adolescents

Clinical Pediatrics (2013)

Poornima Vanguri David A. Lanning Edmond P. Wickham Aruna Anbazhagan Melanie K. Bean

This study explored pediatric health care providers’ obesity treatment practices and perceptions about adolescent weight loss surgery (WLS). Surveys were e-mailed to pediatric listservs. After descriptive analyses, correlations, chi-squares, and one-way analyses of variance compared responses by provider characteristics. Surveys were completed by 109 providers. Almost half do not routinely measure body mass index. Providers typically counsel patients about lifestyle change, with limited perceived benefit; <10% have ever referred patients for WLS, citing cost (20%), risk (49%), or “not indicated in pediatrics” (17%) as reasons. However, when presented with patient scenarios of different ages and comorbidities, likeliness to refer for WLS increased substantially. Surgeons, younger providers and those with fewer years of experience were more likely to refer for WLS ( P < .05). Despite expert consensus recommendations supporting WLS as part of a comprehensive obesity treatment plan, significant pediatric provider resistance to refer obese adolescents remains. Improved referral and management practices are needed.

Weight management

10.1177/0009922813500848

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Citations (26)

The vaginal microbiome in women of reproductive age with healthy weight versus overweight/obesity

Obesity (2021)

Natalie G. Allen Laahirie Edupuganti David Edwards Nicole R. Jimenez Gregory A. Buck

Abstract Objective The aim of this study was to evaluate the differences between the vaginal microbiome of reproductive‐aged women with overweight and obesity (Ow/Ob) compared with healthy weight (HW). Methods In this case‐control study, a cohort of 367 nonpregnant women (18 to 40 years) with Ow/Ob (BMI ≥25 kg/m 2 ) was case‐matched with 367 women with HW (BMI 18.0 to 24.9 kg/m 2 ). The study was a secondary analysis of 16S rRNA vaginal microbiome surveys through the Vaginal Human Microbiome Study (VaHMP). Groups were matched on age, race/ethnicity, income, and nulliparity status. Results Mean age and BMI of Ow/Ob and HW groups were 26.8 versus 26.7 years and 37.0 versus 22.1 kg/m 2 , respectively. The overall vaginal microbiome composition differed between groups (PERMANOVA, p = 0.035). Women with Ow/Ob had higher alpha diversity compared with women with HW (Wilcoxon test, Shannon index p = 0.025; inverse Simpson index p = 0.026). Lactobacillus dominance (≥30% proportional abundance) was observed in a greater proportion of women with HW (48.7%) compared with Ow/Ob (40.1%; p = 0.026). Conclusions The vaginal microbiome differs in reproductive‐aged women with Ow/Ob compared with women with HW, with increased alpha diversity and decreased predominance of Lactobacillus . Observed differences in the vaginal microbiome may partially explain differences in preterm birth and bacterial vaginosis risk between these populations.

10.1002/oby.23306

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Citations (25)

Multiglandular Parathyroid Carcinoma: Case Report and Review of The Literature

Endocrine Practice (2011)

Mehmet Hacıyanlı Gonca Örük Arzu Avci Ucarsoy Emine Özlem Gür Hüdai Genç

Parathyroid carcinoma

Parathyroid gland

Parathyroid neoplasm

10.4158/endp.17.4.37g64w6841360v89

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Citations (0)

Tolvaptan for the Management of Syndrome of Inappropriate Antidiuretic Hormone Secretion: Lessons Learned In Titration of Dose

Endocrine Practice (2011)

Andréa Cintra Bastos Tôrres Edmond P. Wickham Diane M. Biskobing

Tolvaptan

10.4158/ep10386.cr

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Citations (17)

Changes in body anthropometry and composition in obese adolescents in a lifestyle intervention program

European Journal of Nutrition (2013)

Yi Ning Shibing Yang Ronald K. Evans Marilyn Stern Shumei S. Sun

10.1007/s00394-013-0612-9

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Citations (17)

The role of parents in behavioral treatment for adolescent obesity: design and rationale for the TEENS+ randomized clinical trial

BMC Public Health (2023)

Melanie K. Bean Jessica Gokee LaRose Edmond P. Wickham Hollie A. Raynor Laura J. Caccavale

There is an urgent need for innovative approaches to adolescent obesity treatment, particularly among individuals from racially and ethnically marginalized backgrounds, who face increased risk of obesity and its associated morbidity and mortality. There is a particular dearth of research on the long-term efficacy of adolescent obesity treatments. Further, research and clinical practice guidelines consistently recommend parents' inclusion in their adolescents' obesity treatment, yet the most effective strategy to engage parents in adolescent obesity treatment remains unclear. Towards that end, this investigation will conduct a fully-powered, randomized clinical trial to examine the efficacy of two distinct approaches to involving parents in their adolescents' obesity treatment.

Motivational Interviewing

Weight management

Biostatistics

10.1186/s12889-023-16421-0

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Citations (1)