The intestinal absorption characteristics of phenolic acids (PAs) have been elucidated in terms of their affinity for the monocarboxylic acid transporter (MCT). Recently, the involvement of the stomach has been implicated in the absorption of polyphenols. The present work demonstrates that the gastric absorption efficiency of each PA is apparently different between various PAs. Various PAs with different affinities for MCT were administered (2.25 mumol) to rat stomach, and then the plasma concentration of the PA was measured. The plasma concentration of ferulic acid (FA) peaked 5 min after administration in the stomach. At 5 min after administration, the plasma concentration of each PA increased in the order: gallic acid = chlorogenic acid < caffeic acid < p-coumaric acid = FA. This order matches their respective affinity for MCT in Caco-2 cells, which we have demonstrated in previous studies. These results indicated that MCT might be involved in the gastric absorption of PAs, similar to the intestinal absorption.

Chlorogenic Acid

p-Coumaric acid

Coumaric acid

Phenolic acid

10.1021/jf061554+

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Citations (130)

A Study of the Compatibility Between Asphalt and SBS

Petroleum Science and Technology (2003)

Zheng Liu Mingqin Xuan Zhaohui Zhao Yufeng Cong Liao Ke-jian

Abstract Abstract In this article, the compatibilities between different components of a base asphalt and styrene butadiene styrene (SBS) have been analyzed from microscopic structures. Specifically, the asphalt was separated into three components: saturates, aromatics, and resins, by Solvent Recycled Absorption Chromatography Separation Technology (SRACST). The compatibilities between these different components and the polymer were compared with the help of Fluorescence Microscope (FM) with which the existing state of the polymer SBS in these different components could be examined obviously. The modified effects indicated that aromatics could cause SBS swollen and, resins dissolved SBS better than saturates, though both the two components could partially dissolve SBS and the two mixtures presented two immiscible phase systems. In order to further investigate the compatibility between aromatics and SBS, from macroscopic properties, an additive rich in aromatics was added to the SBS/asphalt mixture, and the result was satisfactory. Keywords: CompatibilityAsphalt/SBS mixtureAdditive property

Asphaltene

10.1081/lft-120018176

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Development of magnetic health-care textiles

Zhaohui Zhao

By use of the magnetic health care effect caused by magnetic yarn friction against the body and through CAD design of 3 densities and jucquard weaves,samples of bed sheets,shirts and jeans with magnetic health-care effect are created on SGA598 full-automatic sample loom by use of the spaced collocation of the magnetic blended yarn and pure cotton yarn.The magnetic test proves that it keeps a weak magnetic field that benetits human's health.

LOOM

Textile

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Ferulic Acid Is Quickly Absorbed from Rat Stomach as the Free Form and Then Conjugated Mainly in Liver

Journal of Nutrition (2004)

Zhaohui Zhao Yukari Egashira Hiroo Sanada

Capsule

10.1093/jn/134.11.3083

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Citations (200)

Cholesterol‐lowering effects of Northern wild rice in LDL receptor knockout mice

The FASEB Journal (2012)

Mohammed H. Moghadasian Khuong Le Zhaohui Zhao Tiffany Nicholson Chunyan Goh

We have recently reported that Northern wild rice produced in Manitoba, Canada possesses higher antioxidant properties as compared to conventional white rice. This observation plus other data from available literature suggest that Northern wild rice may have anti‐atherogenic properties. The objective of the current study was to investigate potential lipid‐modifying and anti‐atherogenic properties of Northern wild rice in LDL receptor knockout mice. Sixteen 4‐week male LDL receptor knockout mice were divided into two groups of 8 each. These experimental groups received a semi‐synthetic diet containing 0.06% (w/w) cholesterol; carbohydrates in this diet were replaced with Northern wild rice and used for the “treated group.” The experiment will be carried out for 24 weeks. Plasma total cholesterol and triglyceride levels were estimated at baseline and every four weeks using standard enzymatic kits. Body weight and estimated 24‐hour food consumption were recorded. These data are summarized in the following Table. Data suggest strong cholesterol‐lowering activities for Northern wild rice in this animal model. It is most likely that such reductions in total cholesterol levels will lead to significant reductions in atherogenesis by the end of the study. This study was supported by Agriculture Research and Development Initiative (ARDI), Winnipeg, Manitoba, Canada.

Knockout mouse

White rice

10.1096/fasebj.26.1_supplement.1026.14

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