G Nazionale

Ospedale di Rivoli

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i-10 index

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Document Type

Co-Authors

A Cavalot

IRCCS Humanitas Research Hospital

G Cortesina

University of Turin

Francesca Palonta

Vita-Salute San Raffaele University

Alberto Staffieri

University of Padua

Roberto Albera

University of Turin

E. Ricci

IRCCS Humanitas Research Hospital

Gian Luca Fadda

University of Turin

M Magnano

CTO Andrea Alesini

Mario Bussi

Vita-Salute San Raffaele University

G Preti

Ospedale Koelliker

Cooperative Institutions

University of Turin

Azienda Ospedaliero Universitaria San Giovanni Battista

University of Genoa

University of Milan

Azienda Ospedaliera Citta' della Salute e della Scienza di Torino

Fondazione Ricerca Molinette

Istituti di Ricovero e Cura a Carattere Scientifico

Ospedale di Rivoli

IRCCS Humanitas Research Hospital

Ospedale San Luigi Gonzaga

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[The use of indwelling phonatory valve in the rehabilitation of laryngectomized patients: preliminary results in 30 patients].

PubMed (1997)

A Cavalot M Magnano G Nazionale Stefano Rosso Ferrero

The creation of a tracheo-esophageal fistula, and subsequent positioning of a voice button, has greatly improved the patients' ability to communicate and is the treatment of choice for many. The literature indicates that the success rate for this technique is in the 56-90% range. The present study presents the preliminary results obtained in a group of 30 laryngectomy patients for whom a Provox or Blom-Singer-Indwelling voice button were inserted at a later date. Of these 21 (70%) had undergone pre- or post-operative radiotherapy. On the average insertion of the voice button took place 36 months after the laryngectomy while it was approximately 40 months after radiotherapy. Patient selection was based on widely accepted criteria. In particular, the following factors were take into consideration: patient motivation, positive Taub test, dynamic features of the esophageal wall, video fluoroscopy evaluation. For the Provox voice button the patient was hospitalized for 24 hours while with the Blom-Singer-Indwelling device it was 72 hours. In addition, with the latter device, oral feeding was restored somewhat later although this depends on the difference in positioning. The results of the present study are in line with those presented by other authors. In particular, the immediate success rate was 83% while the long-term success rate reached 96%.

Voice prosthesis

Esophageal speech

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P-215 The role of prehabilitation in frail patient with a head and neck cancer

Oral Oncology (2021)

M Magnano M. Andreis G Nazionale Patrizia Mola Giacomo Machetta

Prehabilitation

10.1016/s1368-8375(21)00498-x

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Isolated primary non-Hodgkin’s malignant lymphoma of the larynx

The Journal of Laryngology & Otology (2001)

A Cavalot G Preti Nicola Vione G Nazionale Francesca Palonta

We report a case of glottic primary laryngeal lymphoma. Although the head and neck region is a frequent site of origin of extranodal non-Hodgkin's lymphomas, laryngeal involvement is exceptional. Including this case, about 90 primary laryngeal lymphomas have been reported in the literature. Microscopic study showed a diffuse malignant lymphoma of high-grade malignancy (WF sub-division H). A diffuse, large, B-cell-type NHL was diagnosed histopathologically.The patient was treated with combination chemotherapy, including cyclophosphamide, doxorubicin, vincristine and prednisolone (CHOP), which resulted in complete clinical remission after two courses. Four courses of combination chemotherapy were subsequently performed, making a total of six courses of combination chemotherapy. No recurrence has been observed during the 16-month follow-up period.

Prednisolone

Working Formulation

Combination chemotherapy

10.1258/0022215011907325

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Citations (32)

Chondrosarcoma of the Larynx. Case Report and Review of the Literature

Tumori Journal (2000)

Antonella De Stefani Gian Luca Fadda A Cavalot G Nazionale Patrizia Mola

Chondrosarcoma of the larynx is a rare tumor; worldwide only about 250-300 cases have been described in the literature. We present a clinical case of laryngeal chondrosarcoma manifesting as a swollen mass of 10 × 7 × 6 cm in the infrahyoid and left lateral cervical region. The patient underwent total laryngectomy, thyroidectomy and bilateral neck dissection. A review of the literature on this disease is also reported.

Neck dissection

Thyroid cartilage

Rare disease

10.1177/030089160008600115

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Citations (3)

Pharyngocutaneous Fistula as a Complication of Total Laryngectomy: Review of the Literature and Analysis of Case Records

Otolaryngology (2000)

A Cavalot Carmine F. Gervasio G Nazionale Roberto Albera Mario Bussi

Pharyngocutaneous fistula is the most common complication of total laryngectomy. The management of this problem increases hospitalization time and delays initiation of postoperative radiotherapy, where indicated. To identify factors predisposing to the development of pharyngocutaneous fistula, we reviewed the postoperative courses of 293 patients who underwent total laryngectomy at our clinic. General factors taken into account were concurrent diseases such as diabetes, liver diseases, or chronic anemia; local factors included radiotherapy before and after surgery, preoperative tracheostomy, type of cervical lymph node removal, and method of pharyngeal closure. We then compared our data with those reported in the literature by other authors. Last, we applied the Fisher exact test to a correlation we found between the higher incidence of fistula in patients with diabetes, liver diseases, or anemia. The local factor that turned out to be statistically most significant for the development of fistula was preoperative radiotherapy.

10.1067/mhn.2000.110617

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Citations (185)

Primary non-Hodgkin's lymphoma of the nasal cavity. Clinical case report and discussion

Rays (2000)

Al Cavalot Erica Ricci G Nazionale Francesca Palonta Gl Fadda

Primary non-Hodgkin's lymphoma of the nasal cavity is a disease more likely to affect men than women; it is characterized by a T cell immunophenotype and is often associated with involvement of the paranasal structures and with high recurrence rates. Many authors report that its extremely poor prognosis depends on tumour stage and extension into the paranasal sinuses. Patients with Ann Arbor stage IE limited to only one nasal cavity have better survival rates than those with the same stage but with tumour extension beyond the nasal cavity. Patients with stages IIE, IIIE and IV have a very poor prognosis that does not seem to be affected by the use of conventional chemotherapy. Optimal treatment for the disease is not yet known. The use of radiotherapy alone has been reported in initial stages of the disease; however, given that its prognosis is burdened by frequent local or systemic recurrence or both, combined modality therapy has been applied in all stages. In this case report we describe a case of primary non-Hodgkin's lymphoma of the nasal cavity localized at the middle turbinate, in combination with an updated literature review.

Immunophenotyping

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Qualitative and Quantitative Evaluation of Some Vocal Function Parameters Following Fitting of a Prosthesis

Journal of Voice (2001)

A Cavalot Francesca Palonta G Preti G Nazionale E. Ricci

Voice prosthesis

10.1016/s0892-1997(01)00061-3

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Citations (4)

[Evaluation of various phonatory parameters in laryngectomized patients: comparison of esophageal and tracheo-esophageal prosthesis phonation]

Recent results in cancer research/Recent Results in Cancer Research (1998)

Gervasio Cf A Cavalot G Nazionale M Magnano Riccardo Ragona

Esophageal speech

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[Evaluation of various phonatory parameters in laryngectomized patients: comparison of esophageal and tracheo-esophageal prosthesis phonation].

PubMed (1998)

Gervasio Cf A Cavalot G Nazionale M Magnano Riccardo Ragona

Today there is increased need for an objective comparison between the various post-total laryngectomy phonatory rehabilitation techniques. This survey involves 20 patients who, after total laryngectomy, underwent rehabilitation using the esophageal voice (n = 10) or through the application of a secondary tracheal-esophageal prosthesis (n = 10). The multivariate analysis indicated that the only phonatory parameter which differed significantly between the two types of voice was the maximum phonation time (MPT) (p < 0.01). The MPT was markedly longer in patients with the tracheal-esophageal prosthesis. In patients with prosthesis, the Mann-Whitney test highlighted better figures for the following parameters: MPT (p = 0.0003), GP (maximum number of words that can be read in one breath) (p = 0.009), maximum intensity level (MIL) (p = 0.019), Shimmer (p = 0.008) and noise-to harmonics ratio (NHR) (p = 0.049). Furthermore, the Spearman test proved there is a relationship between MIL and GP, and between Pitch and Shimmer. Therefore, the tracheal-esophageal prosthesis seems to offer better phonatory energy and phonatory duration for every breath. However, these methods of objective inquiry need to be further developed so that comparison-among the different authors and among the different rehabilitation methods-can be made easier than it is now.

Voice prosthesis

Esophageal speech

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Citations (1)

Primary non-Hodgkin's Lymphoma of the Nasal Cavity: Clinical Case Report and Discussion

Acta Oto-Laryngologica (2000)

A Cavalot Erica Ricci G Nazionale Francesca Palonta Gian Luca Fadda

Immunophenotyping

10.1080/000164800750046081

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Citations (3)