To study the effect of comprehensive nursing based on the concept of feedforward control on postoperative FMA (Fugl-Meyer Assessment) and SF-36 (health status questionnaire) in patients with femoral trochanteric fracture.114 patients with femoral intertrochanteric fracture were enrolled in the study. Patients were divided into control group and observation group according to order of admission, 57 cases in each group. Both groups of patients received proximal femoral nail antirotation surgery, conventional nursing and feedforward control based comprehensive nursing. Nursing effects of the two groups of patients were compared.Anus first exhaust time, the time of getting out of bed and hospitalization time, and after nursing, SAS (Self-Rating Anxiety) and SDS (Self-Rating Depression) score of the observation group were significantly lower than those of the control group (p<0.05). FMA and SF-36 score of the observation group after surgical nursing were significantly higher than those of the control group (p<0.05). The total incidence of complications in the observation group was lower than that in the control group (p<0.05).Comprehensive care based on the concept of feedforward control has a better nursing effect for patients with intertrochanteric fracture, which can shorten the time of patient getting out of bed and hospitalization and reduce the incidence of post-complications.
Functionalization of naringin (Nar) on a nanomaterials surface will decrease their detrimental side effects and escape them from immunological rejection. In this study, we developed a sustainable green chemistry route to fabricate naringin-reduced graphene oxide nanosheets (rGO@Nar) through the easy method. The hydroxyl group of Naringin reduces and generates the functionalization of rGO@Nar, and it was confirmed through various spectroscopic method (FT-IR and Raman) and electroscopic methods (FE-SEM and HR-TEM). After careful evaluation of the nanocomposion, we performed cancer cell growth inhibition properties of the colon cancer cell line and Human vein endothelial cells (HT-29 and HUVEC). Also, we performed the photothermal effects of these nanocomposites on cell proliferation and apoptosis using different biochemical staining. Our in vitro investigational datas are established rGO@Nar effectively exhibited and also with rGO@Nar + NIR the photothermal conversion therapy improved prostate cancer cells abolishing the cancer cells. More interestingly rGO@Nar + NIR was found to surpass the activity of rGO@Nar in colon cancer cells tested a topnotches. Thus, our study suggests that rGO@Nar + NIR could be used as impending anticancer candidate for photothermal ablation of prostate cancer cells. Further examinations of the mechanism indicated that anticancer activity was accomplished by inducing apoptosis in cancer cells.
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