Andréa Z Pereira

Hospital Israelita Albert Einstein

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Nelson Hamerschlak

Hospital Israelita Albert Einstein

A.P.N. Barrére

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

Silvia Maria Fraga Piovacari

Hospital Israelita Albert Einstein

Maria Teresa Zanella

Universidade Federal de São Paulo

F. Lúcio

Hospital Israelita Albert Einstein

Gláucia Carneiro

Universidade Federal de São Paulo

Iain J. Clarke

University of Melbourne

Rachel K. Hoyles

Churchill Hospital

Andrew Achaiah

University of Oxford

Ling‐Pei Ho

University of Oxford

Cooperative Institutions

Hospital Israelita Albert Einstein

Universidade de São Paulo

Universidade Federal de São Paulo

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

Hospital São Paulo

Fundação de Apoio à Universidade Federal de São Paulo

University of Oxford

Hospital Universitário da Universidade de São Paulo

Oxford University Hospitals NHS Trust

Monash University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

MON-PP140: Hematopoietic Sten Cell Transplantation in the Elderly: Nutritional and Geriatric Assessment

Clinical Nutrition (2015)

Andréa Z Pereira Silvia Maria Fraga Piovacari Juliana Moura Nabarrete J.B. Silva Masanori Tanaka

Transplantation

10.1016/s0261-5614(15)30572-0

Cite

Citations (0)

Nutrition in hematology gene and cellular therapy: What to do?

Clinical Nutrition ESPEN (2023)

Andréa Z Pereira Lucila Nassif Kerbauy Nelson Hamerschlak

Hematology

Medical nutrition therapy

10.1016/j.clnesp.2023.09.201

Cite

Citations (0)

Consenso Brasileiro de Nutrição em Transplante de Células-Tronco Hematopoiéticas: crianças e adolescentes

Einstein (São Paulo) (2021)

Juliana Moura Nabarrete Andréa Z Pereira Adriana Garófolo Adriana Seber Ângela Venâncio

RESUMO O Consenso Brasileiro de Nutricao em Transplante de Celulas-Tronco Hematopoieticas: criancas e adolescentes foi elaborado com a participacao de nutricionistas, medicos nutrologos e medicos hematologistas pediatricos de 10 centros brasileiros que sao referencia em transplante de celulas-tronco hematopoieticas. O objetivo foi salientar a importância do estado nutricional e da composicao corporal durante o tratamento, bem como as principais caracteristicas relacionadas a avaliacao nutricional do paciente. As intencoes, ao se estabelecer o consenso, foram aprimorar e padronizar a terapia nutricional [...]

Source

Cite

Citations (0)

Noradrenergic Projections from the A1 Field to the Preoptic Area in the Brain of the Ewe and Fos Responses to Oestrogen in the A1 Cells

Journal of Neuroendocrinology (2001)

J. A. Rawson Christopher Scott Andréa Z Pereira Alexandra E. Jakubowska Iain J. Clarke

Previous studies have shown that there is a population of noradrenergic cells in the caudal A1 field of the brainstem of the ewe that contain oestrogen receptors and project to the preoptic area, where gonadotrophin releasing hormone (GnRH) neurones are located. There are some discrepancies in the literature regarding the extent of this projection and the location of the cells in the A1 region. The issue has been a focus of attention because the positive feedback response to oestrogen that causes the ovulatory GnRH/luteinizing hormone surge may originate from this brainstem region. The aim of the present study was to determine the extent of the projections to the preoptic area and to determine whether the caudal A1 cells are activated by oestrogen. Eleven ovariectomized ewes received an injection of the retrograde tracer FluoroGold into the preoptic hypothalamus and four of these also received an i.m. injection of oestrogen 2 h before tissue collection. A further three sheep received i.m. oil injections to act as controls for those receiving oestrogen. Dopamine-beta-hydroxylase (DBH)-positive, retrogradely labelled cells were found within the A1 field in sheep that received preoptic FluoroGold injections. Cells in the vicinity of the A2 and A6 fields, that were retrogradely labelled with FluoroGold, were not DBH-positive. Thus, cells in the A1 field provide a direct noradrenergic projection to the preoptic area and may be involved in the control of the secretion of GnRH in this species. Cells that project to the preoptic hypothalamus from more rostrally located areas of the brainstem are not noradrenergic. In the animals that received oestrogen, double-labelling immunohistochemistry was performed throughout the A1 field for FluoroGold, DBH and Fos. DBH cells of the A1 field expressed Fos only in the oestrogen-treated animals and not in the oil-treated animals. There was a decline in the number of DBH cells that were retrogradely labelled from the caudal region of A1 towards obex. There was a similar gradient in the number of cells that were double-labelled for Fos and FluoroGold. We conclude that there is a population of noradrenergic cells in the caudal A1 field that project to the preoptic area; this is a larger group of cells than previously reported. Oestrogen elicits an acute Fos response in these cells, which may be involved in the time-delayed positive feedback response on GnRH cells. The caudal-to-rostral gradient in the labelling with FluoroGold and Fos in DBH-positive cells is similar to that seen previously for oestrogen receptor in DBH-positive cells in the A1 field.

Preoptic area

10.1046/j.1365-2826.2001.00588.x

Cite

Citations (45)

Overview of obesity and breast cancer in brazil: 24 years of follow up

Clinical Nutrition ESPEN (2020)

Andréa Z Pereira Bianca Pitito Rogério Ruscitto do Prado André Mattar Roberto Hegg

Dyslipidemia

10.1016/j.clnesp.2020.09.414

Cite

Citations (1)

“Influence of Body Composition Assessed by Computed Tomography on Mortality in Older Adults Undergoing Hematopoietic Stem Cell Transplantation”

Research Square (Research Square) (2021)

Ludmila de Oliveira Muniz Koch Andréa Z Pereira Nelson Hamerschlak Adham do Amaral e Castro Adriano Tachibana

Abstract Aim: The incidence of most hematologic malignancies increases with age. Hematopoietic stem cell transplantation (HSCT) provides a potentially life-prolonging or curative option for many patients in this scenario. Limited data is available on muscle mass and density assessed from CT-images on outcomes after HSCT. We aimed to evaluate the influence of body composition on morbidity and mortality in older adults undergoing (HSCT). Methods: Retrospective longitudinal study conducted with 50 patients ≥ 60 years undergoing HSCT at Hospital Israelita Albert Einstein, São Paulo. Body composition was assessed by chest computed tomography and treatment related mortality, graft versus host disease, neutrophil grafting, and overall survival were analyzed. Results: 148 HSCT patients were evaluated, 50 patients were eligible: 60% with autologous and 40% with allogeneic transplantation. Body mass index in patients was (female: 26.9 ± 4.7 kg/m2; 30.1± 4.9 kg/m2) - autologous and (female: 24.3 ± 5.15 kg/m 2 ; male: 26.4 ± 2.0 kg/m 2 ) - allogeneic. In autologous transplant group, we found a positive association between age and death risk with an increase of 63.5% in this risk (p=0.006) and also Karnofsky performance scale with decrease of 11.9% in death risk (p<0.001). A negative association between muscle radiodensity and death risk was observed in allogeneic transplantation patients with risk decrease of 20.1% (p = 0.032). We found a positive association between T4 muscle area and radiodensity with risk of acute graft versus host disease (p= 0.028). Conclusion: In population studied, body composition assessed by chest tomography showed the importance of radiodensity for better prognosis.

10.21203/rs.3.rs-293335/v1

Cite

Citations (0)

The Difficult Decision Not to Prescribe Artificial Nutrition by Health Professionals and Family: Bioethical Aspects

Frontiers in Nutrition (2022)

Andréa Z Pereira Selma Freire de Carvalho da Cunha Henrique Grunspun Marco Aurélio Scarpinella Bueno

Bioethics and nutrition are essential issues in end of life, advanced dementia, life-sustaining therapies, permanent vegetative status, and unacceptably minimal quality of life. Even though artificially administered nutrition (AAN), for this type of health condition, does not improve quality of life and extension of life, and there is evidence of complications (pulmonary and gastrointestinal), it has been used frequently. It had been easier considering cardiopulmonary resuscitation as an ineffective treatment than AAN for a healthy team and/or family. For this reason, many times, this issue has been forgotten.This study aimed to discuss bioethical principles and AAN in the involved patients.The AAN has been an essential source of ethical concern and controversy. There is a conceptual doubt about AAN be or not be a medical treatment. It would be a form of nourishment, which constitutes primary care. These principles should be used to guide the decision-making of healthcare professionals in collaboration with patients and their surrogates.This difficult decision about whether or not to prescribe AAN in patients with a poor prognosis and without benefits should be based on discussions with the bioethics committee, encouraging the use of advanced directives, education, and support for the patient, family, and health team, in addition to the establishment of effective protocols on the subject. All of this would benefit the most important person in this process, the patient.

Bioethics

Health Professionals

Artificial nutrition

10.3389/fnut.2022.781540

Cite

Citations (2)

PP084-MON VITAMIN D DEFICIENCY IN PATIENTS UNDERGOING HEMATOPOIETIC STEM CELL TRANSPLANTATION

Clinical Nutrition (2013)

Andréa Z Pereira A.A. Ribeiro Fábio R. Kerbauy J.B. Silva Silvia MF Pivocari

10.1016/s0261-5614(13)60395-7

Cite

Citations (0)

Impacto da composição corporal na sobrevida e na toxicidade do tratamento no câncer de pâncreas: estudo transversal

A.P.N. Barrére Silvia Maria Fraga Piovacari Pedro Luiz Serrano Usón Rene Claúdio Gansl Andréa Z Pereira

Transversal (combinatorics)

Source

Cite

Citations (0)

Photobiomodulation minimizes taste changes during hematopoietic cell transplantation: A randomized clinical trial

Journal of Biophotonics (2024)

Mariana Henriques Ferreira Letícia Mello Bezinelli Fernanda de Paula Eduardo Andréa Z Pereira Nelson Hamerschlak

Abstract Prevention and treatment protocols for taste changes observed during hematopoietic cell transplantation (HCT) are not well‐established. The purpose of this study was to assess the efficacy of photobiomodulation (PBM) in relieving taste changes and preventing lingual papillae atrophy. HCT patients received PBM ( n = 42) on the tongue dorsum using an InGaAIP laser (660 nm, 100 mW, 1.1 W/cm 2 , 8.8 J/cm 2 ). During the HCT conditioning (T0), severe neutropenia (T1), and after neutrophil engraftment (T2), taste acuity for sweet, bitter, sour, and salty solutions, and clinical appearance of lingual papillae were compared with those of a placebo group ( n = 43). PBM significantly reduced hypogeusia, ageusia, and parageusia at T1 and T2, and also successfully prevented papillae atrophy during all the analyzed HCT periods. In conclusion, PBM enhanced taste acuity during HCT. The decrease in papillae atrophy indicated a potential regenerative effect of this therapy on tongue mucosa .

Taste disorder

10.1002/jbio.202400095

Cite

Citations (1)