Objective:To investigate changes of the cerebral white matter anisotropy in the depressives by using diffusion tensor MR imaging.Methods:9 depressives were studied using MR diffusion tensor imaging compared with 10 healthy adults.The fractional anisotropy(FA) values were measured.The ROIs were put in the frontal,temporal,occipital lobe and callosum respectively.Results:Comparing with healthy adult,significant difference of the FA values of white matter was found in bilateral frontal lobe,temporal lobe and splenium of corpus callosum in the depressives.Conclusion:There is a tenuous FA value reduction in the depresives compared with healthy adult,and the FA values in the left frontal lobe and temporal lobe are different from the right ones.
