A 76-year-old man was referred to our endoscopic unit with hematochezia and anemia. He had been receiving palliative treatment, including radiation therapy, for a primary stage IV parotid gland cancer. Colonoscopy showed that the mucosa of the terminal ileum had prolapsed into the colonic lumen, and a flat elevated lesion, 8 mm in diameter and mimicking a small flat adenoma, was seen on the prolapsed ileal mucosa (Figure [1]). On palpation with biopsy forceps, the lesion felt more solid and harder than an ordinary adenoma. An endoscopic biopsy sample was sent for histological evaluation, and the findings were consistent with a metastatic parotid gland cancer (Figure [2]), the histological features being quite similar to those of the primary tumor biopsied previously. No definite source of bleeding was detected on upper and lower gastrointestinal endoscopic examinations. Palliative treatment was continued and the patient died 4 months later.
A 16 × 16 parallel multiplier, using 1.5μm design rule N-well CMOS technology, will be covered. A multiply time of 45ns has been achieved by using Booth's algorithm and Wallace tree reduction. The typical power dissipation is 100mW.
Vision is said to account for 80% of the information acquired of the five human senses. The presentation of light is an effective way to convey visual information. A blinking presentation especially attracts attention. A low-vision person acquires peripheral information through residual vision. In this case, light effectively supports the travel of low-vision persons. A blinking light stimulates more than a continuous light. However, a blinking light is not sufficiently compatible with the surrounding environment. This research investigates an environmentally friendly blinking pattern to arouse attention.
Female adnexal tumour of probable Wolffian origin is a rare tumour that arises from remnants of the Wolffian duct. Clinical and pathological findings of this tumour have been documented, but the MR findings have not been previously reported. We report the MRI features of an adnexal tumour of probable Wolffian origin.
One of the indicators that affects the comfort of a wheelchair is tire pressure. The purpose of this study was to measure the vibration generated in the wheelchair due to the difference in tire pressure using the pneumatic pressure indicator dedicated to the English valve and the influence of the road surface and vibration of the manually self-propelled wheelchairs.
This study is to investigate new schemes for distributing cryptographic keys in sensor networks. Sharing a key is the very first step to realize secure communication over an untrusted network infrastructure, but commonly used cryptographic techniques cannot be employed for sensor networks due to the restriction of computational resources of sensor nodes. A practical solution to this issue is to predistribute cryptographic keys in sensor nodes before they are deployed. A focal point in this solution is the choice of keys that are assigned to a sensor node. Eschenauer et al. considered to choose keys randomly, and Chan et al. also followed the random choice approach. We consider in this paper a new approach in which keys are assigned according to a basic algebraic geometry. The performance of the proposed scheme is investigated analytically.
The mechanisms of conduction change depending on the extracellular K+ and Ca2+ concentrations ([K+]o and [Ca2+]o, respectively) were investigated. Simultaneous measurements of active and passive membrane properties and net membrane excitability were fulfilled by arranging the intra- and extracellular microelectrodes in a superfused and paced guinea pig papillary muscle. Internal longitudinal resistance (ri), as a parameter of passive property, was evaluated by the intra- and extracellular voltage ratio. The maximum upstroke rate (Vmax) was used as an active property. Apparent threshold potential (Vth) was defined by the breakpoint in the action potential upstroke fitted semilogarithmically. Graded rise in [K+]o (from 2.7 to 15.0 mM) evoked a progressive fall in Vmax, and was associated with less negative resting membrane potential and constant ri. Conduction velocity (theta) was the maximum in 9.0 mM [K+]o ("supernormal" conduction) but not in 2.7 mM [K+]o which gave the greatest Vmax ("subnormal" conduction). Safety factor of conduction (S), as an index of net excitability, could most readily account for the [K+]o-dependent change in theta. This was true also in the case of [Ca2+]o elevation (from 0.9 to 5.4 mM). These results indicate that the cation-modulated propagation is governed by the cable theory including S as a matrix of combined active and passive properties.
We report a patient with metastatic colon carcinoma who was treated effectively with a continuous intrahepatic artery-infusion of 5-FU, Leucovorin and cisplatin, and systemic chemotherapy with CPT-11. A 50-year-old man was diagnosed as having well differentiated adenocarcinoma of the sigmoid colon with multiple liver metastases in March, 1997. Left hemicolectomy and subsequent catheterization into the common hepatic artery via the gastroduodenal artery were performed in April, 1997. He was treated with 3 courses of continuous intrahepatic artery-infusion of 5-FU, Leucovorin and cisplatin, and two courses of systemic chemotherapy with CPT-11 during hospitalization, followed by 6 courses of a similar intraarterial therapy in an outpatient setting. Reinstallation of the catheter into the hepatic artery via the femoral artery was performed because of occlusion of the reservoir. During the 6th course of intraarterial therapy, diarrhea, nausea, and vomiting appeared and angiography revealed a narrowing of the hepatic artery. Therefore, the intrahepatic artery-infusion therapy was reinitiated with doses of 5-FU, Leucovorin and cisplatin reduced to approximately 80%. After 5 courses of this therapy, the computed tomography scan showed a marked decrease in the size of the metastatic hepatic lesions by 90%, and the serum level of CEA decreased from 657.7 ng/ml to 4.5 ng/ml. No severe side effects were seen during the treatment. Though multiple lung metastases were indicated during the intrahepatic artery-infusion therapy, both the liver and lung metastases have been well controlled with continuous intrahepatic artery-infusion chemotherapy and systemic chemotherapy. The continuous intrahepatic arterial infusion of 5-FU, leucovorin and cisplatin appears to be very effective for the treatment of colon carcinoma with liver metastasis without reducing the quality of life.
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