Eva S. Quiroz

Epidemic Intelligence Service

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Roger I. Glass

National Institutes of Health

L Castillo

Brandon Lenox

Altaf A. Lal

Sun Pharma Advanced Research (India)

Rama Ganguly

National Cancer Centre Singapore

STEPHEN BRANTLEY

Jacqueline S. Noel

Centers for Disease Control and Prevention

Jianfeng Li

Shanghai Jiao Tong University

Tamie Ando

Centers for Disease Control and Prevention

Dominic M. Castellano

Eastern Virginia Medical School

Cooperative Institutions

Centers for Disease Control and Prevention

University of South Florida

National Center for Immunization and Respiratory Diseases

National Center for Infectious Diseases

Florida College

Center for Global Health

Moffitt Cancer Center

National Center for Emerging and Zoonotic Infectious Diseases

Emory University

Global Viral

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An Outbreak of Cryptosporidiosis Linked to a Foodhandler

The Journal of Infectious Diseases (2000)

Eva S. Quiroz Caryn Bern John R. MacArthur Lihua Xiao Madeleine M. Fletcher

In September and October 1998, a cryptosporidiosis outbreak occurred on a Washington, DC, university campus. In a case-control study of 88 case patients and 67 control subjects, eating in 1 of 2 cafeterias was associated with diarrheal illness (P < .001). Morbidity was associated with eating dinner on 22 September (odds ratio, 8.1; 95% confidence interval, 3.4–19.5); weaker associations were found for 6 other meals. Cryptosporidium parvum was detected in stool specimens of 16 (70%) of 23 ill students and 2 of 4 ill employees. One ill foodhandler with laboratory-confirmed C. parvum prepared raw produce on 20–22 September. All 25 Cryptosporidium isolates submitted for DNA analysis, including 3 from the ill food-handler, were genotype 1. This outbreak illustrates the potential for cryptosporidiosis to cause foodborne illness. Epidemiologic and molecular evidence indicate that an ill foodhandler was the likely outbreak source.

Cryptosporidium parvum

Attack rate

10.1086/315279

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Citations (148)

Viral Meningitis-Associated Hospitalizations in the United States, 1988–1999

Neuroepidemiology (2003)

Nino Khetsuriani Eva S. Quiroz Robert C. Holman Larry J. Anderson

We used the National Hospital Discharge Survey and the Nationwide Inpatient Sample of the Health Care Cost and Utilization Project to estimate disease burden associated with viral meningitis hospitalizations in the United States. During 1988–1999, viral meningitis accounted for an estimated 434,000 hospitalizations (annual average, 36,000; average annual hospitalization rate, 14/100,000), and 2.1 million hospital days (annual average, 175,000). The estimated mean charge for viral meningitis-associated hospitalization during 1993–1997 varied between USD 6,562 and 8,313, resulting in annual estimated hospitalization costs between USD 234 and 310 million and a total estimated cost of nearly USD 1.3 billion for the 5-year period. In summary, viral meningitis remains an important cause of morbidity and financial burden and merits efforts to improve diagnostic, treatment, and prevention options.

Viral meningitis

10.1159/000072924

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Citations (80)

[Radiculomyelitis following acute hemorrhagic conjunctivitis caused by enterovirus 70. Report of the 1st corroborated case in America].

PubMed (1984)

Romo Sáenz L Castillo Eva S. Quiroz

Enterovirus 71

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Toxoplasmic Lymphadenopathy Clinically Presenting as Lymphoma

Cancer Control (1997)

Eva S. Quiroz Dominic M. Castellano John N. Greene Ramón L. Sandin Lynn C. Moscinski

The clinical spectrum of Toxoplasma gondii infection ranges from no symptoms to a syndrome of fever and lymphadenopathy to diffuse multisystem organ involvement. Lymphadenopathy occurs in 10% to 20% of acute cases and may be accompanied by constitutional symptoms. The differential diagnosis is broad, considering the diverse presentation. Symptomatic toxoplasmosis occurs with increased frequency in patients with hematologic malignancies and solid tumors that display defects in cell-mediated immunity. We present a case of toxoplasmic lymphadenitis clinically presenting as non-Hodgkin’s lymphoma and briefly review the literature.

Toxoplasmosis

Generalized lymphadenopathy

Constitutional symptoms

Mediastinal lymphadenopathy

Presentation (obstetrics)

Cervical lymphadenopathy

10.1177/107327489700400510

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Citations (1)

Pneumocystis carinii Pneumonia With an Atypical Granulomatous Response

Southern Medical Journal (1996)

Michael T. Flannery Eva S. Quiroz Lisa Grundy STEPHEN BRANTLEY

Pneumonia due to Pneumocystis carinii may present atypical radiographic and pathologic findings. We report the case of a 32-year-old man with acquired immune deficiency syndrome (AIDS) whose chest roentgenogram showed a bilateral diffuse nodular pattern suggestive of miliary tuberculosis. Diagnosis ultimately required open lung biopsy, which showed evidence of an atypical granulomatous reaction with Pneumocystis carinii in the absence of other organisms. P carinii pneumonia must be considered in the differential diagnosis of patients with AIDS with nodular pulmonary densities and evidence of an atypical granulomatous reaction on pathologic specimens.

Miliary tuberculosis

Lung biopsy

10.1097/00007611-199604000-00011

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Citations (16)

HIV infection, risk factors, and testing in a veteran population.

PubMed (2002)

Rama Ganguly Brandon Lenox Eva S. Quiroz John T. Sinnott

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"Norwalk-Like Viruses" - Public Health Consequences and Outbreak Management

PsycEXTRA Dataset (2001)

Umesh D. Parashar Eva S. Quiroz Anthony W. Mounts Stephan S. Monroe Rebecca L. Fankhauser

"Norwalk-like viruses" (NLVs) cause outbreaks of gastroenteritis and are spread frequently through contaminated food or water. Molecular diagnostics now enables detecting viruses in clinical and environmental specimens, linking of NLV strains causing outbreaks in multiple geographic locations, and tracing them to their sources in contaminated food or water. This report reviews recent advances in NLV detection and provides guidelines and recommendations for investigating NLV-related outbreaks, including specimen collection and disease prevention and control. This report also updates information provided in CDC's previously published, Viral Agents of Gastroenteritis: Public Health Importance and Outbreak Management (MMWR 1990;39 [No. RR-5]: 1-24). These CDC recommendations are intended for public health professionals who investigate outbreaks of acute gastroenteritis but could be useful in academic and research settings as well.

Contact tracing

Acute gastroenteritis

Norwalk virus

Public health surveillance

Waterborne diseases

10.1037/e548262006-001

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Citations (190)

Spontaneously Draining Abdominal Wound: Case Report and Differential Diagnosis

Infectious Diseases in Clinical Practice (1999)

Julie Larkin Seth J. Kanowitz Eva S. Quiroz

1From the Division of Infectious Disease, Department of Medicine, University of South Florida College of Medicine, Tampa, Florida 2From the Centers for Disease Control and Prevention, Atlanta, Georgia

Atlanta

Disease Control

10.1097/00019048-199908000-00012

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Citations (0)