Martha Eunice Rodríguez-Arellano

Institute for Social Security and Services for State Workers

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Paula Costa‐Urrutia

RedCLARA

Julio Granados

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

Angélica Saraí Jiménez‐Osorio

Universidad Autónoma del Estado de Hidalgo

Claudette Musalem-Younes

Institute for Social Security and Services for State Workers

Valentina Franco‐Trecu

Universidad de la República

Osvaldo Erik Sánchez-Hernández

Institute for Social Security and Services for State Workers

Jacqueline Solares-Tlapechco

Institute for Social Security and Services for State Workers

Valentina Colistro

Universidad de la República

Helios Cárdenas-Hernández

Universidad Autónoma de la Ciudad de México

José Pedraza‐Chaverrí

Universidad Nacional Autónoma de México

Cooperative Institutions

Institute for Social Security and Services for State Workers

Broad Institute

Universidad Nacional Autónoma de México

Harvard University

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

Massachusetts General Hospital

Instituto Politécnico Nacional

Mexican Social Security Institute

University of Oxford

Centro Medico Nacional Siglo XXI

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Association between knowledge and dietary practices and the body mass index in the staff of a tertiary health care center

Revista de especialidades m�dico-quir�rgicas (2015)

mo Almudena Gutiérrez-Noriega-de-Lomo ez Bernarda Sánchez-Jiménez no María Reyna Sámano-Sámano Martha Eunice Rodríguez-Arellano Osvaldo Erik Sánchez-Hernández

Center (category theory)

Tertiary care

Source

Cite

Citations (0)

IL-36γ is secreted through an unconventional pathway using the Gasdermin D and P2X7R membrane pores

Frontiers in Immunology (2022)

Laura D. Manzanares Claudia I. Gutiérrez-Román Albertana Jiménez‐Pineda Felipe Castro-Martínez Genaro Patiño‐López

Mucosal innate immunity functions as the first line of defense against invading pathogens. Members of the IL-1 family are key cytokines upregulated in the inflamed mucosa. Inflammatory cytokines are regulated by limiting their function and availability through their activation and secretion mechanisms. IL-1 cytokines secretion is affected by the lack of a signal peptide on their sequence, which prevents them from accessing the conventional protein secretion pathway; thus, they use unconventional protein secretion pathways. Here we show in mouse macrophages that LPS/ATP stimulation induces cytokine relocalization to the plasma membrane, and conventional secretion blockade using monensin or Brefeldin A triggers no IL-36γ accumulation within the cell. In silico modeling indicates IL-36γ can pass through both the P2X7R and Gasdermin D pores, and both IL-36γ, P2X7R and Gasdermin D mRNA are upregulated in inflammation; further, experimental blockade of these receptors' limits IL-36γ release. Our results demonstrate that IL-36γ is secreted mainly by an unconventional pathway through membrane pores formed by P2X7R and Gasdermin D.

10.3389/fimmu.2022.979749

Cite

Citations (4)

Dyslipidemia, Obesity, and Ethnicity in Mexican Children

International Journal of Environmental Research and Public Health (2021)

Paula Costa‐Urrutia Valentina Colistro Valentina Franco‐Trecu Julio Granados Rafael Álvarez Fariña

The aim of this study was to assess lipid disorders in children from five ethnic groups, both urban and indigenous, from northern and central Mexico. We measured the lipid profile to determine the ability of the body mass index (BMI) to discriminate an abnormally high lipid level using receiving operating characteristics (ROC). We analyzed the association and interaction of obesity and ethnicity with lipid disorders using generalized linear models in 977 children. The highest prevalence of lipid disorders (high TG, high TC, high LDL, high APOB, and dyslipidemia) was found in central Mexico-Mexico City and urban northern Mexico. The BMI performed better at predicting low HDL in Seris, a northern indigenous group (0.95, CI: 0.69-0.85), and Mexico City (0.75, CI: 0.69-0.82), and high LDL in Puebla (central Mexico, 0.80, CI: 0.69-0.85). Obesity significantly (

Dyslipidemia

Lipid Profile

10.3390/ijerph182312659

Cite

Citations (28)

Relación entre la vitamina D y la absorción de metales y metaloides en el embarazo

Perinatología y Reproducción Humana (2024)

Angélica Saraí Jiménez‐Osorio Diego Estrada-Luna Martha Eunice Rodríguez-Arellano

10.24875/per.24000009

Cite

Citations (0)

Prevalence of obesity in preschoolers, students and adolescents at Hospital Regional Licenciado Adolfo López Mateos from ISSSTE

Revista de especialidades m�dico-quir�rgicas (2015)

Ismael Camacho-Guerrero Juan José Rodríguez-Zepeda Erick Oswaldo-Sánchez Martha Eunice Rodríguez-Arellano Claudette Musalem-Younes

Source

Cite

Citations (1)

Desarrollo de un programa de educación acuática en la escuela indígena de la comunidad seri

Revista de Investigación en Actividades Acuáticas (2021)

Paula Costa Urrutia Viviana Becerra Fabián Becerra Osiris González Carolina Ratti

Antecedentes: Las prácticas acuáticas contribuyen al desarrollo motriz y disminuyen la probabilidad de ahogamientos. Su implementación es particularmente importante en comunidades costeras, dada la relación de sus integrantes con el entorno marino. Objetivos: Por lo que se llevó a cabo una escuela de verano que tuvo como objetivo la adaptación, de la comunidad indígena Seri de Punta Checa, norte de México, al medio acuático en un entorno natural. Método: Las actividades fueron retos motores para desarrollar habilidades y destrezas de supervivencia en el ambiente acuático; estaciones de habilidades de juego grupal; y enseñanza de técnica. Resultados: Participaron 48 niños en total, con un promedio de asistencia de dos días por semana. Ninguno de los participantes sabía nadar antes del programa y todos adquirieron habilidades de supervivencia básicas. Los niños mayores de 8 años desarrollaron habilidades motrices y lograron completar circuitos con estaciones cuyas distintas los obligaban a poner en práctica estas habilidades. Los niños de 6 a 8 años alcanzaron una fase preliminar de desarrollo, puesto que fueron capaces de realizar algunas actividades en lugares poco profundos. Por medio de dibujos, los niños expresaron sus intereses, y la natación estuvo entre sus actividades preferidas. Conclusiones: Los niños, las familias, los docentes y las autoridades educativas consideraron que el programa había tenido resultados positivos, lo cual resalta la importancia de incluir la adaptación al medio acuático en el plan de estudios. Esto, contribuiría a la seguridad acuática y el desarrollo de la competencia motriz de los niños, sino también a una mayor disposición al aprendizaje curricular.

10.21134/riaa.v4i8.1309

Cite

Citations (0)

Effect of 15 BMI-Associated Polymorphisms, Reported for Europeans, across Ethnicities and Degrees of Amerindian Ancestry in Mexican Children

International Journal of Molecular Sciences (2020)

Paula Costa‐Urrutia Carolina Abud Valentina Franco‐Trecu Valentina Colistro Martha Eunice Rodríguez-Arellano

In Mexico, the genetic mechanisms underlying childhood obesity are poorly known. We evaluated the effect of loci, known to be associated with childhood body mass index (BMI) in Europeans, in Mexican children from different ethnic groups. We performed linear and logistic analyses of BMI and obesity, respectively, in Mestizos and Amerindians (Seris, Yaquis and Nahuatl speakers) from Northern (n = 369) and Central Mexico (n = 8545). We used linear models to understand the effect of degree of Amerindian ancestry (AMA) and genetic risk score (GRS) on BMI z-score. Northern Mexican Mestizos showed the highest overweight-obesity prevalence (47.4%), followed by Seri (36.2%) and Central Mexican (31.5%) children. Eleven loci (SEC16B/rs543874, OLFM4/rs12429545/rs9568856, FTO/rs9939609, MC4R/rs6567160, GNPDA2/rs13130484, FAIM2/rs7132908, FAM120AOS/rs944990, LMX1B/rs3829849, ADAM23/rs13387838, HOXB5/rs9299) were associated with BMI and seven (SEC16B/rs543874, OLFM4/rs12429545/rs9568856, FTO/rs9939609, MC4R/rs6567160, GNPDA2 rs13130484, LMX1B/rs3829849) were associated with obesity in Central Mexican children. One SNP was associated with obesity in Northern Mexicans and Yaquis (SEC16B/rs543874). We found higher BMI z-score at higher GRS (β = 0.11, p = 0.2 × 10−16) and at lower AMA (β = −0.05, p = 6.8 × 10−7). The GRS interacts with AMA to increase BMI (β = 0.03, p = 6.08 × 10−3). High genetic BMI susceptibility increase the risk of higher BMI, including in Amerindian children.

Genetic genealogy

SNP

10.3390/ijms21020374

Cite

Citations (15)

High prevalence of humoral autoimmunity in first-degree relatives of Mexican type 1 diabetes patients

Acta Diabetologica (2018)

Norma Cristina Segovia-Gamboa Martha Eunice Rodríguez-Arellano Andrés Muñoz-Solís Jorge E. Retana-Jiménez Germán Vargas‐Ayala

First-degree relatives

10.1007/s00592-018-1241-9

Cite

Citations (2)

Tolerogenic dendritic cells induce antigen-specific hyporesponsiveness in insulin- and glutamic acid decarboxylase 65-autoreactive T lymphocytes from type 1 diabetic patients

Clinical Immunology (2014)

Norma Cristina Segovia-Gamboa Martha Eunice Rodríguez-Arellano Rafael Rangel-Cruz Manuel Sánchez‐Díaz Julio César Ramírez-Reyes

Mixed lymphocyte reaction

Priming (agriculture)

10.1016/j.clim.2014.06.009

Cite

Citations (24)

Obesity measured as percent body fat, relationship with body mass index, and percentile curves for Mexican pediatric population

PLoS ONE (2019)

Paula Costa‐Urrutia Alejandra Vizuet-Gámez Miryam Ramirez-Alcántara Miguel Ángel Guillén-González Óscar Medina‐Contreras

In Mexico, the increase in childhood obesity is alarming. Thus, improving the precision of its diagnosis is expected to impact on disease prevention. We estimated obesity prevalence by bioimpedance-based percent body fat (%BF) and body mass index (BMI) in 1061 girls and 1121 boys, from 3 to 17 years old. Multiple regressions and area under receiver operating curves (AUC) were used to determine the predictive value of BMI on %BF and percentile curves were constructed. Overall obesity prevalence estimated by %BF was 43.7%, and by BMI it was 20.1%; it means that the diagnosis by BMI underestimated around 50% of children diagnosed with obesity by %BF (≥30% for girls, ≥25% for boys). The fat mass excess is further underestimated in boys than in girls when using the standard BMI classification. The relationship between %BF and BMI was strong in school children and adolescents (all cases R2>0.70), but not in preschool children (girls R2 = 0.57, boys R2 = 0.23). AUCs showed greater discriminative power of BMI to detect %BF obesity in school children and adolescents (all cases AUC≥0.90) than in preschool children (girls AUC = 0.86; boys AUC = 0.70). Growth percentile charts showed that girls aged 9-17 years and boys aged 8-17 years presented fat excess from the 50th percentile and above. We suggested to change the BMI cut-off for them, considering values at the 75th percentile as overweight, and values at the 85th percentile as obesity, as previously recommended for Mexican children. Improving obesity diagnosis will allow greater efficiency when searching for comorbidities in clinical practice.

10.1371/journal.pone.0212792

Cite

Citations (51)